Uric Acid

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Overview
Interpretations
FAQ's
Uric Acid

Overview of Uric Acid

What is Uric Acid?

Uric acid is a nitrogenous compound which is formed as a byproduct of metabolic activities and is eliminated by the kidneys. The buildup of uric acid levels in blood gives rise to a number of health conditions. The Uric Acid Test is performed to measure the levels of uric acid in the blood.

Sample Type

The sample type collected for Uric Acid is: Blood

Preparation for Uric Acid

  • No special preparation required

Why Get Tested for Uric Acid?

The Blood Uric Acid Test is performed:

·       To diagnose gout upon the appearance of symptoms

·       In cancer patients being treated by chemotherapy or radiotherapy to monitor their uric acid levels

·       To check the efficacy of medications that lower uric acid levels

·    To assess the risk of kidney stones or to determine the cause of recurrent kidney stones

Understand more about Uric Acid

Uric acid is a nitrogenous compound produced by the metabolic breakdown of purine. Purines are nitrogenous bases in DNA forming parts of the structural framework of the cells. Breakdown of purines occurs when cells become old and die, forming uric acid. Uric acid is also formed from the metabolic breakdown of some types of food like red meat, seafood, beans, etc.

Most of the uric acid in the blood is filtered and eliminated by the kidneys and a small remaining amount in the stool. The concentration of uric acid in the blood can increase due to overproduction of uric acid or improper elimination of uric acid, and this condition is called Hyperuricemia. Hyperuricemia can also be caused due to cancer treatment by chemotherapy or radiotherapy. These treatment methods kill the cancer cells, which may leak the uric acid into the blood.

Excess uric acid can form crystals in the synovial fluid between the joints causing inflammation and pain. This condition is called gout and can severely damage the joints if left untreated. Blood Uric Acid Test can indicate the presence of gout, or risk of formation of gout. However, it is not a definitive test for gout. Confirmatory test for gout is performed by analysis of synovial fluid (joint fluid) for monosodium urate crystals. Chronic Hyperuricemia can cause the formation of tophi, which are hard lumpy deposits of uric acid crystals formed under the skin, in the joints, and at the top of the ears. Tophi cause severe damage to the joints and may compress nerves causing chronic pain and disfigurement. The excess uric acid may also deposit and crystallize in the kidneys causing kidney stones and acute renal failure.


What Results of Uric Acid mean?

Interpretations

Normal uric acid range:

·         Adult Female: 2.4 to 6.0 mg/dL

·         Adult Male: 3.4 to 7.0 mg/dL

Children: 2.0 to 5.5 mg/dL


Higher than normal levels of uric acid in the blood is called Hyperuricemia and may be caused due to kidney diseases, gout, chemotherapy or radiotherapy treatment.


Patient Concerns about Uric Acid

Frequently Asked Questions about Uric Acid

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle attached is used to withdraw blood sample from a blood vessel in your arm generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood and hence makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution and then the needle is inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample once collected is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, as this test involves a needle prick to withdraw the blood sample, rarely, a patient may experience increased bleeding, hematoma (blood collection under the skin) formation, bruising or infection at the site of needle prick.
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Gen-X Diagnostics is a unit of ARA Healthcare Pvt. Ltd. founded by leading applied research scientist Dr. Rama Mukherjee. Gen-X specializes in the field of molecular diagnostics, focusing on the development of genetic, biological and molecular diagnostic services. It is one of the first of its kind R&D Company focusing on development of genetic, biological and molecular diagnostic services with an intention to assisting its global partners in shortening the cycle and lowering the cost of drug discovery and development by providing cost effective and efficient co-development and outlicencing solution. Gen X Diagnostics is a unique leading Molecular Diagnostics in India offering a wide range of tests for infectious diseases, transplantation medicine, prenatal diagnostics, cancer, genetic disorder, metabolic and hormonal disorders. Gen-X Diagnostics has started its diagnostics operation from Dec 2007. We do reflect a commitment to improving the lives through the delivery of innovative diagnosis and therapeutic products that enable and provide optimal care.

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