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Lactate Dehyderogenase

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Test Results & Interpretations
Patient Concerns

Overview of Lactate Dehyderogenase

Test Description

This test measures the amount of an enzyme called lactate dehydrogenase that is an important marker for tissue injury anywhere in the body. It may be ordered, along with other tests such as a comprehensive metabolic panel (CMP), when your doctor suspects that a disease or condition is causing some degree of cellular or tissue damage. LDH levels may also occasionally be ordered when an individual has experienced muscle trauma or injury or when a person has signs and symptoms of hemolytic anemia. LDH testing may be ordered on a regular basis when an individual has been diagnosed with cancer.

Why Get Tested

  1. As a part of comprehensive metabolic panel 
  2. In many diseases, when your doctor suspects some cellolar or tissue damage
  3. If you have signs or symptoms of hemolytic anemia 
  4. In certain cases, when some cancers are suspected 
  5. If you have symptoms of meningitis like neck stiffness, severe headache, high fever, vomiting, rashes, then spinal fluid may be checked for LDH


  • No special preparation required

What Results of Lactate Dehyderogenase mean?


  • Increased levels of Lactate Dehydrogenase usually indicate some type of tissue damage. Therefore, they may be elevated in a variety of conditions like hemolytic anemia, megaloblastic anemia, infections, acute kidney and liver diseases, testicular cancers and lymphoma. A high LDH level may indicate that the treatment for cancer has not been successful. The LDH level may also remain persistently high in some chronic and progressive conditions. 
  • Low levels of LDH usually do not indicate a problem. It may be seen when someone ingests large amount of ascorbic acid (Vitamin C) 

Patient Concerns about Lactate Dehyderogenase

Frequently Asked Questions

Q. Is LDH used to diagnose heart attack?
Earlier LDH was used to diagnose an acute heart attack, but new, far more sensitive and specific tests have completely replaced it as a test for heart muscle injury.

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