Terminal Deoxynucleotidyl Transferase

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Overview
Interpretations

Overview of Terminal Deoxynucleotidyl Transferase

What is Terminal Deoxynucleotidyl Transferase?

The Terminal Deoxynucleotidyl Transferase (TDT) test is performed to classify lymphomas and leukemias, to differentiate between lymphoblastic and non-lymphoblastic leukemia, to diagnose acute lymphoblastic leukemia, lymphoblastic lymphomas and lymphoid blast crisis of CML (Chronic Myelgenous Leukemia).

Sample Type

The sample type collected for Terminal Deoxynucleotidyl Transferase is: Blood

Preparation for Terminal Deoxynucleotidyl Transferase

  • No special preparation required

Why Get Tested for Terminal Deoxynucleotidyl Transferase?

The test is performed when a patient exhibits symptoms of leukemia such as-
>Joint pain
>Fatigue
>Dizziness
>Fever
>Frequent infections
>Mouth ulcer
>Swollen lymph nodes
>Unexplained weight loss
>Pallor
>Loss of appetite




What Results of Terminal Deoxynucleotidyl Transferase mean?

Interpretations

The results depend upon the stain used for the classification and distinction of leukemias and lymphomas. So, a positive result is indicated by the presence of positive staining of the ALL B-cells and negative staining, i.e., no staining in case of absence of TdT positive cells.


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