Test Detail
Overview
Interpreting Results

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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Alkaline Phosphatase Isoenzymes

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Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is Alkaline Phosphatase Isoenzymes?

This test is mostly ordered as a part of liver function tests; when you have symptoms of a liver disorder like loss of appetite, nausea, vomiting, abdominal pain, jaundice, itching or bone disease like bone pains. 


Why is Alkaline Phosphatase Isoenzymes done?

  1. As a part of liver function test 
  2. If you have signs or symptoms of a liver disorder like loss of appetite, nausea, vomiting, fatigue, abdominal pain, jaundice, itching 
  3. If you have signs or symptoms of bone disease like bone pain, increased frequency of fractures



Interpreting Alkaline Phosphatase Isoenzymes results


Interpretations

  • High Alkaline Phosphatase (ALP) usually indicates either the liver has been damaged or there is bone disease
  • Greatly increased ALP level may be associated with blockage of bile ducts as in gall stones or cancer and in Paget's disease of bones
  • Moderately elevated level can be seen in liver diseases like hepatitis, cirrhosis and in other conditions like ulcerative colitis, congestive heart failure, Hodgkin's lymphoma 
  • Low levels of ALP may be seen temporarily in blood transfusion or heart bypass surgery 




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