Test Detail
Overview
Interpreting Results
FAQ's

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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Typhi Dot

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Typhi Dot
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is Typhi Dot?

Typhi Dot test is done for Salmonella typhi. This test detects IgM and IgG antibodies against Salmonella typhi. This test is not a quantitative test. It only detects the presence or absence of Salmonella typhi.


Why is Typhi Dot done?

The Typhi dot test is done:

  • In case of signs or symptoms of typhoid (enteric) fever such as headache, high fever, abdominal pain, diarrhea, weight loss, or skin rashes

  • As a part of fever panel


What does Typhi Dot Measure?

The Typhi dot test measures IgM and IgG antibodies against Salmonella typhi. These antibodies are produced against the outer membrane protein (OMP) of Salmonella typhi. This test usually shows results within 2-3 days of infection. It identifies IgM and IgG antibodies separately. The presence of IgM antibodies indicates a recent infection while the presence of IgG antibodies indicates a remote infection. 

As this test is not a quantitative test, it only detects the presence or absence of Salmonella typhi. Widal test is advised in case titers (small portion) of specific antibodies is required. 


Interpreting Typhi Dot results


Interpretations

  • Positive Salmonella typhi IgM test suggests recent infection with bacteria Salmonella Typhi causing typhoid fever 

  • Negative Salmonella typhi IgM test usually indicates no infection with the bacteria


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Typhi Dot


Frequently Asked Questions about Typhi Dot

Q. Is there any preparation required before the test?
Inform the doctor about the medications you may be taking. No other specific preparations are usually required before this test.
Q. How can you prevent typhoid fever?
Avoiding contaminated foods and drinks can help to prevent typhoid fever. Along with that, proper vaccination against typhoid fever can also keep a check on developing any possible case of infection.
Q. What are the other tests to diagnose Enteric fever?
The other tests which are used to diagnose Enteric fever include Blood culture test, Widal test, Stool culture test, and Urine culture test. Among these, blood culture is the most commonly recommended method for diagnosing Enteric fever and is performed during the first week of fever. If in case other test results come inconclusive then bone marrow samples can be used to diagnose any infections.
Q. How is the blood sample taken?
The healthcare provider takes a blood sample from the arm. The site from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then followed by inserting a small needle which has a tube attached to it for collecting blood. Once the sufficient blood for analysis is withdrawn, the needle is removed. The site is then covered with a gauze pad.
Q. Is there any risk associated with the withdrawal of blood sample procedure?
As such there is no risk but in few cases, bruising, bleeding, and infection at the puncture site can be seen. In very few cases, there can be swelling of the vein after the blood is withdrawn.
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