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Anti-CCP Antibody in Dehradun
Also known as Cyclic citrullinated peptide antibody, Anti-citrullinated peptide antibody, Citrulline antibody, Anti-cyclic citrullinated peptide
You need to provide
Blood
This test is for
Male, Female
Test Preparation
Understanding Anti-CCP Antibody in Dehradun
What is Anti-CCP Antibody in Dehradun?
An Anti-CCP Antibody test diagnoses rheumatoid arthritis (RA) and differentiates it from other types of arthritis. It detects the presence of anti-cyclic citrullinated peptide (Anti-CCP) antibodies in the blood, which are associated with autoimmune diseases, particularly rheumatoid arthritis (RA), and are often present in the early stages of the disease.
What does Anti-CCP Antibody measure?
An Anti-CCP Antibody test measures the presence of antibodies against cyclic citrullinated peptides (CCP) in the blood. These antibodies are collectively referred to as anti-CCP antibodies. Citrullination is a process where the amino acid arginine is converted to citrulline. In autoimmune diseases, such as rheumatoid arthritis (RA), the immune system may mistakenly identify citrullinated peptides as foreign invaders and produce antibodies against them.
Anti-CCP antibodies are considered one of the early markers of rheumatoid arthritis. They contribute to the chronic inflammation and joint damage characteristic of RA. Their presence in the blood can aid in the early diagnosis of RA, establish a prognosis for disease progression, and allow timely intervention and management.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Anti-CCP Antibody in Dehradun
Frequently Asked Questions about Anti-CCP Antibody in Dehradun
Q. Is there any preparation required before an Anti-CCP Antibody test?
Inform the doctor about the medications you may be taking. No other specific preparations are usually required before this test.
Q. Is there any risk associated with an Anti-CCP Antibody test?
No, there is no risk associated with an Anti-CCP Antibody test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. What is citrulline?
During inflammation, arginine amino acid residues can be enzymatically converted into citrulline residues in proteins, such as vimentin, by a process called citrullination. Its production occurs during the metabolism of the amino acid arginine. It will change the structure of the protein which can trigger an immune response that produces autoantibodies against proteins in the joints.
Q. What is rheumatoid arthritis?
Rheumatoid arthritis is a systemic autoimmune disease which is chronic (from a long time). It causes inflammation, stiffness, pain and disastrous changes in joints of the body. It can occur at any age but the usual age is after 40 years. As compared to men, women are more affected. It can progress slow or fast. But, if untreated can cause disability of the joints.
Q. What are other tests advised for rheumatoid arthritis?
Apart from anti CCP antibody test, rheumatoid factor (RF) test, joint X rays, and blood tests are advised. If a patient has positive anti CCP antibody test as well as RF test it indicates that the patient has rheumatoid arthritis. If the patient has a positive anti CCP antibody test but negative RF test it means that the patient is likely to develop rheumatoid arthritis in the future. If anti CCP antibody test is negative but RF test is positive, it can indicate that the patient should be analyzed for other inflammatory conditions as well.
Q. Is an Anti-CCP Antibody test screening test for rheumatoid arthritis?
No, the screening test for rheumatoid arthritis is the rheumatoid factor. But, once the RF is positive, an Anti-CCP Antibody test should be done to differentiate rheumatoid arthritis from other arthritis.
Q. Can I book an Anti-CCP Antibody test in Dehradun?
Yes, you can book an Anti-CCP Antibody test in Dehradun with Tata 1mg Labs. The test can be booked easily, is affordable, and comes with an easy-to-understand report.
Q. Is home sample collection possible for an Anti-CCP Antibody test in Dehradun?
Yes, home sample collection is possible for an Anti-CCP Antibody test in Dehradun with Tata 1mg Labs. You can also choose a date and time that suits your schedule for sample collection.
Q. How can I book an Anti-CCP Antibody test with Tata 1mg Labs in Dehradun?
The booking process for an Anti-CCP Antibody test with Tata 1mg Labs in Dehradun is straightforward and hassle-free. Follow these steps to schedule a test online: 1). Go to the Lab Tests section on the Tata 1mg website. 2). Add your preferred test to the shopping cart. 3). Choose a time and day that works for you as long as you also take the essential prerequisites into account. 4). A confirmation notification will be sent to you with all the details once the booking is complete.
Q. What is the cost of an Anti-CCP Antibody test in Dehradun?
Tata 1mg Labs allows you to book tests at an affordable price in Dehradun. An Anti-CCP Antibody test can be booked at a pocket-friendly budget of Rs. 1750.
Q. How long does it take Tata 1mg Labs to provide the reports of an Anti-CCP Antibody test in Dehradun?
We at Tata 1mg Labs recognize the value of prompt results. We strive to deliver test results with quick turnaround times so you can receive the information promptly. The reports of an Anti-CCP Antibody test in Dehradun are often provided in 36 hours.
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References
- Niewold TB, Harrison MJ, Paget SA. Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis. QJM. 2007 Apr;100(4):193-201. [Accessed 29 Sept. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/17434910/#:~:text=Anti%2Dcyclic%20citrullinated%20peptide%20
- CCP [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 29 Sept. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=ccp
- Abdul Wahab A, Mohammad M, Rahman MM, Mohamed Said MS. Anti-cyclic citrullinated peptide antibody is a good indicator for the diagnosis of rheumatoid arthritis. Pak J Med Sci. 2013 May;29(3):773-7. [Accessed 29 Sept. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809312/
- Rheumatoid Arthritis: Diagnosis, Treatment, And Steps to Take [Internet]. NIH; Nov. 2022. [Accessed 29 Sept. 2023]. Available from: https://www.niams.nih.gov/health-topics/rheumatoid-arthritis/diagnosis-treatment-and-steps-to-take
- Manivelavan D, C K V. Anti-cyclic citrullinated Peptide antibody: an early diagnostic and prognostic biomarker of rheumatoid arthritis. J Clin Diagn Res. 2012 Oct;6(8):1393-6. [Accessed 29 Sept. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471491/
- van Venrooij WJ, van Beers JJ, Pruijn GJ. Anti-CCP Antibody, a Marker for the Early Detection of Rheumatoid Arthritis. Ann N Y Acad Sci. 2008 Nov;1143:268-85. [Accessed 29 Sept. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/19076355/
- Chauhan K, Jandu JS, Brent LH, et al. Rheumatoid Arthritis [Internet]. Treasure Island, Florida: StatPearls Publishing; 2023 Jan. [Accessed 29 Sept. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441999/
- Rheumatoid Factor - an overview [Internet]. ScienceDirect; [Accessed 29 Sept. 2023]. Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/rheumatoid-factor
- Rheumatoid arthritis (RA) [Internet]. CDC; 27 Jul. 2020 [Accessed 29 Sept. 2023]. Available from: https://www.cdc.gov/arthritis/basics/rheumatoid-arthritis.html
- Chou C, Liao H, Chen Ch, Chen W, Wang H, Su K. The Clinical Application of Anti-CCP in Rheumatoid Arthritis and Other Rheumatic Diseases. Biomark Insights. 2007 May 3;2:165-71. [Accessed 29 Sept. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717818/
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