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Interpreting Results
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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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C- Reactive Protein Quantitative

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This test is for
Male, Female
Test Preparation
  1. Overnight fasting is preferred.


What is C- Reactive Protein Quantitative?


C-reactive protein (CRP) Test detects the presence of CRP in blood. CRP is a nonspecific marker of inflammation and it can rise in response to inflammatory conditions including infection, trauma, heart and autoimmune diseases. Other tests are performed along with CRP to diagnose a particular condition and determine the location. It also helps to monitor the treatment post an infection and inflammation.
During the previous wave of pandemic, it was seen that people with elevated levels of CRP showed many-fold increase in the risk of developing severe COVID infection. Hence, getting tested for CRP during COVID infection and recovery phase can be crucial to identify the risk of severe disease.

Why is CRP done?

The C-reactive Protein Test is done:

·         To help detect the presence of an acute bacterial infection

·         To help detect autoimmune diseases

·         To monitor treatment for infection, inflammation, autoimmune diseases, and cancer

What does CRP Measure?

CRP Test measures the levels of CRP in blood to detect the presence of an inflammation or to monitor the treatment and progress of an inflammatory condition. C-reactive Protein or CRP is an acute phase reactant protein which is produced and secreted by the liver in response to an inflammation in the body, which may be caused by tissue injury, infection, or autoimmune diseases. CRP levels increase in patients with trauma, heart attack, autoimmune diseases, bacterial infections, sepsis, post surgery, cancer, etc. CRP levels are often increased before the onset of other symptoms of inflammation such as pain, fever, etc. CRP levels in blood fall as the inflammation subsides.

It is a non-specific test. It can neither diagnose a condition by itself nor can it determine the location of a particular inflammation or disease. Other tests along with physical examination are performed to diagnose a particular condition and determine the location.

A variant of the CRP test is the High Sensitivity C-reactive Protein Test (hs-CRP) which is more sensitive for CRP levels and can detect blood CRP levels at a lower concentration than the standard CRP Test. The hs-CRP Test is performed usually to determine the risk of development of cardiovascular diseases in otherwise healthy individuals.

Interpreting CRP results


Normal CRP level: Below 10 mg/L

Higher CRP levels than the normal range indicate the presence of an inflammation which may be caused by an infection, trauma, autoimmune diseases, cancers, etc.

The CRP Test is used to detect the presence of an inflammatory condition. Other tests and physical examinations are performed to diagnose a particular condition.

CRP levels are monitored at regular intervals to determine flare-ups in a chronic inflammatory condition, as well as to monitor response to treatment.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about CRP

Frequently Asked Questions about C- Reactive Protein Quantitative

Q. What are the common symptoms of high CRP levels?
Some of the common symptoms of high CRP levels include pain, muscle weakness, stiffness or soreness, unexplained tiredness, low-grade fever, headaches, chills, insomnia, loss of appetite, and unexplained weight loss. However, if the CRP levels are severely increased, the person may experience severe headaches, body pain, sweating, chills or shaking, high-grade fever, persistent vomiting or diarrhea, breathing difficulty, rapid heart rate, severe muscle stiffness or soreness, etc.
Q. What factors can affect the CRP levels in blood?
Blood CRP levels can be affected by certain medications such as birth control pills; nonsteroidal anti-inflammatory drugs (NSAIDs); hormone-replacement therapy (HRT); conditions like obesity, diabetes, pregnancy; or activities like smoking, alcohol consumption, heavy exercise, etc.
Q. What additional tests can be prescribed by the doctor in case the result of the CRP test is not normal?
Additional tests that may be prescribed in case of abnormal CRP test results are the erythrocyte sedimentation rate (ESR) test, rheumatoid factor (RF) test, and anti-cyclic citrullinated peptide antibody (anti-CCP Antibody) test.
Q. What are chronic inflammatory diseases?
Chronic inflammatory diseases are conditions that lead to the development of long-lasting or frequently recurring inflammation such as rheumatoid arthritis, lupus, and inflammatory bowel disease.
Q. How can I naturally reduce my CRP levels?
Always consult your doctor if your CRP levels are high. However, some lifestyle modifications such as making healthy food choices, adding fiber and vitamin-rich foods to your daily diet, exercising regularly to maintain healthy body weight, limiting alcohol intake and smoking, and managing stress may help reduce your CRP levels.
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