What is AST, SGOT?
This test is also known as AST, Serum Glutamic-Oxaloacetic Transaminase test, SGOT, GOT, and Aspartate Transaminase test. This test is done to detect liver damage and diagnose liver disease.
Why is AST, SGOT done?
In case of symptoms of the liver disorder such as pain in the abdomen, nausea and vomiting, yellow skin (jaundice)
Risk of exposure to hepatitis virus
As a part of comprehensive check-up (comprehensive metabolic panel)
What does AST, SGOT Measure?
Aspartate aminotransferase (AST) is an enzyme which is found in most of the body cells but mainly in the heart and liver. It is also present in kidneys and muscles but in smaller amounts. Normally, the levels of AST are low, but the levels rise when there is an injury to cells of the liver or muscle.
The function of the liver is to process the nutrients of the body. It also produces bile which helps in digesting fats along with the production of other important proteins such as blood clotting factors and albumin. The liver breaks the potentially toxic substances into harmless products which can be used or eliminated by the body.
The rise in levels of AST can be due to conditions causing liver damage such as hepatitis, drugs which are toxic to liver, cirrhosis, or alcoholism. The AST test is not specific for the liver. Its levels may also rise in conditions which affect other parts of the body.
This test is done with alanine aminotransferase (ALT) test. Both the enzymes are found in the liver and their levels rise in case of liver damage. The ratio of AST/ALT helps in differentiating between the causes of liver damage in case of injury to heart or muscle.
Interpreting AST, SGOT results
AST (SGOT), Serum < 50 U/L
*Reference range may vary from lab to lab