Test Detail

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Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Lalit Mohan Gupta
MBBS, MD - Microbiology
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Smooth Muscle Actin

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This test is for
Male, Female
Test Preparation
  1. No special preparation required


What is SMA?

Smooth muscle antibodies (SMA) are certain antibodies that might attack its own actin (a protein present in your body). Actin is a protein found in the smooth muscles of your body, mostly found in the liver. The smooth muscle actin test detects the amount of antibodies present against the actin.

Why is SMA done?

  1. To diagnose any form of autoimmune disease that might be present
  2. To differentiate these diseases from the other causes of liver injury
  3. The test should be carried out when following symptoms are observed dark urine, abdominal swelling, pale colored stool and enlarged liver




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