Test Detail
Overview

Content created by

Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Acetyl Choline Receptor Antibody

(AchR Ab, ARAb)
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You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Overview


What is AchR Ab, ARAb?

Myasthenia gravis (MG) is characterised by muscle weakness & easy fatigability
most commonly due to autoantibody mediated loss of functional acetylcholine
receptors in the postsynaptic membrane of skeletal muscle. ACHR antibodies are
not found in Congenital MG. This assay is used to diagnose Acquired forms of MG
(90% positive), for detecting subclinical MG in recipients of D-penicillamine,
Thymoma without clinical evidence of MG & Graft versus Host disease. It may also
be positive in Lambert-Eaton myasthenic syndrome, Autoimmune liver disease &
Paraneoplastic autoimmune neurological disorders.


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