What is E3?
Unconjugated estriol (uE3) is a form of oestrogen (hormone) produced by the fetus (unborn baby) through metabolism. Estriol levels are used to determine birth defects and chromosomal variations in babies. Estriol is ejected from the placenta (an organ acting as the protective covering for the fetus) into the mother’s blood, and measured as unconjugated uE3. This test is mainly used for diagnosing Down syndrome, where the levels are lesser than the normal level, which in pregnant females is < 14.60ng/ml.
A blood sample is shared with the lab for analysis. There are no specific risks involved in taking this test, and it is considered one of the best ways to analyse an unborn baby’s health.