Test Detail
Overview
Interpreting Results

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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Lalit Mohan Gupta
MBBS, MD - Microbiology
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Quad Marker With Graph

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You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Please keep the hard copy of your latest pregnancy ultrasound report ready at the time of your test.

Overview


What is Quad Marker With Graph?

This test measures the levels of four important substances in the placenta namely alpha fetoprotein, human chorionic gonadotrophin,  estriol and inhibin A. You should get this test done if you are between 15 to 20 weeks pregnant as it analyses the probability of the unborn baby to have certain genetic disorders like Down’s, Edward’s syndrome, neural tube defects and sometimes multiple pregnancies.


Why is Quad Marker With Graph done?

  1. If you are pregnant between 15 to 20 weeks of gestation to screen against chromosomal disorders like Down's syndrome, Edward syndrome and other neural tube defects

Interpreting Quad Marker With Graph results


Interpretations

    • Positive quadruple marker test usually indicates that the unborn child has high risk of neural tube defects and chromosomal disorders like Down's syndrome, Patau syndrome etc. More specific tests like amniocentesis are then advised to make a definitive diagnosis
    • High level of inhibin A usually indicates Down's syndrome whereas low levels might be associated with Edward's syndrome or trisomy 18. Sometimes, variable levels of inhibin A may also be present and they are usually associated with trisomy 13 or Patau syndrome

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