Treponema Pallidum Heamagglutinition
What is TPHA?
The Treponema Pallidum Agglutination Assay is performed to screen for and diagnose an infection by the Treponema pallidum bacterium causing a sexually transmitted disease, Syphilis.
Why is TPHA done?
The test is performed when symptoms of syphilis appear, including a chancre on the throat or the genitals, or a skin rash typical of syphilis. The test is also performed in case there is a risk of contracting a sexually transmitted disease through unsafe sexual intercourse, in case of a previous positive diagnosis of AIDS, and as a part of routine tests during pregnancy.
Interpreting TPHA results
A positive result is indicated by the gelatin particles clumping together in the test dish, indicating presence of antibodies against the bacterium in the blood of the patient caused due to an infection.