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Coombs Test - Indirect

400
4.8
NABL, CAP
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Overview
Test Results & Interpretations

Overview of Coombs Test - Indirect

Test Description

The Indirect Coombs test is performed to screen for the presence of antibodies against Red Blood Cells (RBCs). If present, these antibodies will target and destroy foreign RBCs which could be acquired through blood transfusions. These antibodies if present in the mother's blood, can target the RBCs of the fetus.

Why Get Tested

• To screen the recipient of a blood transfusion before the transfusion is done
• To screen the mother’s blood for antigens that can target the RBCs of the newborn
• For evaluation of hemolytic anemia


Precautions

  • No special preparation required

What Results of Coombs Test - Indirect mean?

Interpretations

Positive results for the Indirect Coombs test indicates that antibodies against one or more antigens being screened are present in the blood sample being tested. When tested positive in a pregnant woman, it indicates the presence of Rh antibody in the mother’s blood that may destroy the RBCs of the baby in some cases.

Provided By

NABL

CAP

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