Test Detail
Tests Included

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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Protein Total, Serum

Protein Total, Serum Test Includes 4 testsView All
You need to provide
This test is for
Male, Female
Test Preparation
  1. No special preparation required


What is Protein Total, Serum?

Protein Total, Serum test is also known as TP. This test is done as a part of general health checkup and is done to determine the nutritional status of an individual. It is also done to screen and help detect certain liver and kidney diseases and disorders.

Why is Protein Total, Serum done?

The Protein Total, Serum Test is done:

  • As a part of routine physical examination

  • In case of unexpected weight loss 

  • In case of fatigue

  • In case of symptoms of liver or kidney disorder

What does Protein Total, Serum Measure?

The Protein Total, Serum Test measures the total amount of the various types of proteins in the serum. Proteins are known as building blocks of all cells and tissues. They are very important for the growth and development of the body. The proteins are responsible for forming the structural part of most of the organs and help in making up of enzymes and hormones which regulate the functions of the body.

In the blood, two classes of proteins are found which include albumin and globulin. Around 60% of the total protein is formed of albumin which is produced by the liver. Albumin works as a carrier protein for various small ions and molecules. It also acts as a source of amino acids for tissue metabolism and as the principal component which is involved in the maintenance of osmotic pressure.

The rest of the proteins present in the plasma are globulins which include enzymes, antibodies, carrier proteins, hormones, and various other types of proteins. In the blood, the protein total serum levels are relatively stable, which means that there is a fine balance in the loss and production of the protein molecules.

If this delicate balance is disturbed due to any illness or disease then this test is done to analyze the reason for it.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Protein Total, Serum

Frequently Asked Questions about Protein Total, Serum

Q. In what conditions, there is a decrease in the levels of Protein total seen?
The decrease in the levels of Protein total may be seen in conditions such as malnutrition, severe liver disease, kidney disease, and congestive heart failure.
Q. In what conditions, there is an increase in the levels of Protein total seen?
The increase in levels of Protein Total can be seen in conditions such as inflammatory disorders, multiple myeloma, and dehydration.
Q. Can having a high protein diet lead to increase in levels of Protein Total?
No, high protein diet does not affect the levels of Protein Total in the body.
Q. How is the blood sample taken?
The healthcare provider takes a blood sample from the arm. The site from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then followed by inserting a small needle which has a tube attached to it for collecting blood. Once the sufficient blood for analysis is withdrawn, the needle is removed. The site is then covered with a gauze pad.
Q. Is there any risk associated with the withdrawal of blood sample procedure?
As such there is no risk but in few cases, bruising, bleeding, and infection at the puncture site can be seen. In very few cases, there can be swelling of the vein after the blood is withdrawn.
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Tests Included (4 tests)

  • Globulin, Serum
  • Albumin/Globulin Ratio, Serum
  • Albumin
  • Protein Total



For over a hundred years, human pathology has been one of the keystones of medicine and rightly so at SRL, we offer our patients world-class Pathology services because their well-being is of the utmost importance to us. Pathology is quite simply the scientific study of the overall response of your body to any foreign influence, i.e., disease. Actually, we use this knowledge to diagnose & subsequently treat your ailment. What we basically do is carefully compare the normal structure and function...
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Simply great in all aspects
Pawan Kumar
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