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Erythrocyte Sedimentation Rate

100
4.1
NABL, CAP, ISO
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Overview
Interpreting Results
FAQ's
Erythrocyte Sedimentation Rate

Overview of ESR

What is ESR?

Erythrocyte Sedimentation Rate (ESR) Test, also known as sedimentation rate test or sed rate test is a blood test which can detect inflammatory activity in the body. ESR test doesn’t diagnose one specific condition. Instead, it helps to diagnose or monitor the progress of an inflammatory disease.

Why is ESR done?

The Erythrocyte Sedimentation Rate (ESR) Test is performed:

  • To detect any inflammation in the body which may be caused due to conditions such as infections, cancers, and autoimmune diseases

  • To monitor the progress of inflammatory diseases

  • To evaluate the response to treatment of inflammatory diseases





What does ESR Measure?

The ESR test measures the rate at which red blood cells (erythrocytes) settle (sediment) at the bottom of a tube that contains a blood sample in one hour. The test result is expressed in millimeters per hour (mm/hr).

In the presence of inflammation, certain proteins mainly fibrinogen increase in blood. This high proportion of fibrinogen in the blood causes the red blood cells to form a stack (rouleaux formation) which settle quickly due to their high density.

The ESR test is a non-specific measure of inflammation. An ESR can be affected by conditions other than inflammation also. Although a high ESR can detect the presence of inflammation, it cannot provide any information regarding the cause and site of inflammation. Hence, an ESR test is done along with other tests.

Preparation for ESR

  • No special preparation required

Sample Type for ESR

The sample type collected for Erythrocyte Sedimentation Rate is: Blood

Interpreting ESR results

Interpretations

The normal reference range for Erythrocyte Sedimentation Rate (ESR) is:


Men

0-15 millimetres per hour (mm/hr), or 0-20 mm/hr for men older than 50

Women

0-20 mm/hr, or 0-30 mm/hr for women older than 50

Children

0-10 mm/hr

Newborns

0-2 mm/hr


High ESR can be seen in:


  • Inflammatory disease such as Arthritis (Inflammation of joints), vasculitis (Inflammation of blood vessels)

  • Infection, such as pneumonia, pelvic inflammatory disease, appendicitis, skin infection, bone infection, heart valve infection

  • Autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis

  • Chronic kidney disease

  • Viral infections

  • Pregnancy

  • Cancer, such as lymphoma or multiple myeloma



Low ESR can be seen in:

  • Congestive heart failure

  • Polycythemia

  • Sickle cell disease

  • Severe liver disease

  • Hypofibrinogenemia


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about ESR

Frequently Asked Questions about Erythrocyte Sedimentation Rate

Q. How is this test performed?
This test is performed on a blood sample. A syringe with a fine needle is used to withdraw blood sample from a blood vessel in your arm, generally from the inner side of the elbow area. The doctor, nurse or the phlebotomist will tie an elastic band around your arm which will help the blood vessels to swell with blood. This makes it easier to withdraw blood. You may be asked to tightly clench your fist. Once the veins are clearly visible, the area is cleaned with an antiseptic solution. The needle is then inserted into the blood vessel to collect the sample. You may feel a tiny pinprick during the procedure. Blood sample, once collected, is then sent to the laboratory.
Q. Is there any risk associated with this test?
There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
Q. What are the factors which may affect the ESR test results?
The following factors may affect the ESR test results: Pregnancy, anemia, menstrual period, certain medications such as estrogens, birth control pills, aspirin, prednisone etc.
Q. Is there any preparation required before the ESR test?
No special preparation is required for ESR test. However, you should inform the doctor about the medications you are taking as some medications such as estrogens, birth control pills, aspirin, prednisone etc. may affect the test result.
Q. Which is the other test that can be prescribed to detect inflammatory activity?
Your doctor may prescribe C - Reactive protein blood test to detect inflammation.
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Provided By

NABL

CAP

ISO

About Oncquest Labs

With a decade of experience under its belt, Oncquest is known for its excellence in Clinical Diagnostics. From its first avatar as an R&D focused entity, Oncquest has evolved into a reference laboratory in the field of Oncology, and more recently into a multi-platform Pathology Services provider with a core focus in Molecular Pathology and Surgical Pathology Services. Its logistic capabilities and geographical spread makes Oncquest an ideal associate for clinical activities in India. Oncquest’s accredited quality systems ensure customer satisfaction through any of its customer-centric service offerings. Oncquest’s recent advances in the areas of Companion Diagnostics and Pharmacogenomics have also allowed for and encouraged greater penetration of Personalized Medicine into the Indian healthcare market, making it the future epicentre of the many technological advancements in healthcare, to come. Its close association with many Hospitals across India stands testament to the faith that Oncquest has instilled in the doctors and patients which avail of its services. Oncquest is fast becoming a cornerstone for a blooming healthcare industry. With over a decade of experience in the field of molecular diagnostics and pathology services, Oncquest Laboratories has earned its reputation of clinical excellence in the Indian market. Our advanced technologies and global quality systems have ensured that we stay ahead of the curve, and this has resulted in our association with some of the most advanced clinicians, hospitals and research organizations in the country. As India gets set for a clinical revolution, ushering in a trend of new healthcare services and products, Oncquest has defined its place as a partner of choice for those who bring value to our proud subcontinent. Our national reach and sizeable knowledge base allows us to be at the forefront of scientific advances, and an ideal partner for clinical activities. We strive to be connected with the best in the industry and we welcome partnership in ideas and technologies. For example, Oncquest’s early adoption and utilization of genetic sequencing technologies has resulted in many “first to market” assays, which have subsequently been adopted in several treatment and monitoring protocols. Innovation is an essential part of our DNA. We welcome challenges, and look forward to associating with you and your organizations to develop pioneering solutions and to tackle some of the most pressing issues faced in our world.

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