Test Detail
Understanding the Test
Test Measures
Other Tests
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Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Anemia Panel 1

Anemia Panel 1 Includes 31 testsView All
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Do not eat or drink anything other than water for 8-12 hours before the test

Understanding Anemia Panel 1


What is Anemia Panel 1?

Anemia or deficiency of hemoglobin is one of the most common causes of fatigue and it can occur due to many causes. This package is ideally designed to detect the cause of anemia and to monitor the progress it’s treatment. Additionally, it also screens for diabetes mellitus, heart diseases and vitamin deficiencies. 


What does Anemia Panel 1 measure?

Contains 31 tests
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Protein Total, Serum

A Protein Total, Serum test measures the amount of proteins in the body. Proteins are known as the building blocks of all cells and tissues. They play a crucial role in the growth and development of most of your organs and in making enzymes and hormones. There are two types of proteins found in the body, namely albumin and globulin. About 60% of the total protein is made up of albumin, which is produced by the liver. It helps to carry small molecules such as hormones, minerals, and medicines throughout the body. It also serves as a source of amino acids for tissue metabolism. On the other hand, globulin is a group of proteins that are made by the liver and the immune system. They play an important role in liver functioning, blood clotting, and fighting off infections.

Know more about Protein Total, Serum

  • Albumin/Globulin Ratio, Serum

  • The Albumin/Globulin Ratio, Serum test is performed if a liver or kidney disease is suspected. It quantifies the concentrations of two essential blood proteins, albumin and globulin. The test is a comparison figure in which albumin present in your body is divided by the amount of globulin to get the Albumin/Globulin) ratio. This ratio helps assess how well these two proteins are balanced and helps evaluate liver or kidney health.

  • Protein Total

  • The Protein Total test measures the total amount of major proteins in your body, namely, albumin and globulin. It is also used to detect diseases related to improper protein metabolism and diseases that affect the liver, kidneys, or immune system. A higher than normal level of protein total in your body may indicate medical conditions such as viral hepatitis, cirrhosis, HIV/AIDS, multiple myeloma, etc. On the other hand, a lower-than-normal level can indicate conditions like liver disease, malnutrition, kidney disease, or an autoimmune disorder.

  • Globulin, Serum

  • A Globulin, Serum test measures the levels of globulin protein in the blood. Globulin is one of the major proteins (about 40% of the total protein) found in the body and is produced by the liver and immune cells. It usually exists in different forms: alpha globulins, beta globulins, and gamma globulins. These forms play an important role in liver and kidney functioning, blood clotting, and fighting off infections. 

  • Serum Albumin

  • A Serum Albumin test measures the level of albumin protein in your blood. Albumin is one of the major proteins found in your body; about 60% of the total protein is made up of albumin, which is produced by the liver. It helps carry small molecules, such as hormones, vitamins, minerals, and medicines, throughout the body. It also serves as a source of amino acids for tissue metabolism. Albumin helps stop the fluid from leaking out of the blood vessels. When the albumin level is insufficient, the fluid can leak out of your blood vessels and build up in your lungs, belly, or other parts of your body.

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CBC (Complete Blood Count)

A CBC (Complete Blood Count) test evaluates red blood cells (RBCs), white blood cells (WBCs}, and platelets. Each of these blood cells performs essential functions–RBCs carry oxygen from your lungs to the various body parts, WBCs help fight infections and other diseases, and platelets help your blood to clot–so determining their levels can provide significant health information. A CBC test also determines the hemoglobin level, a protein in RBC that carries oxygen from the lungs to the rest of your body. Evaluating all these components together can provide important information about your overall health.

Know more about CBC (Complete Blood Count)

  • RDW CV

  • An RDW CV test which is part of red cell indices, helps identify characteristics of red blood cells. RDW (red cell distribution width) measures the variations in the sizes of red blood cells, indicating how much they differ from each other in a blood sample. RDW is expressed as RDW-CV, a coefficient of variation. A higher RDW may suggest more variation in red cell sizes, while a lower RDW indicates more uniform red cell sizes.

  • Hematocrit

  • A Hematocrit test measures the proportion of red blood cells (RBCs) in your blood as a percentage of the total blood volume. It is a crucial part of a complete blood count (CBC) and helps in assessing your blood health. RBCs are responsible for carrying oxygen from the lungs to different parts of the body. The hematocrit test provides valuable information about your blood's oxygen-carrying capacity.

    Higher-than-normal amounts of RBCs produced by the bone marrow can cause the hematocrit to increase, leading to increased blood density and slow blood flow. On the other hand, lower-than-normal hematocrit can be caused by low production of RBCs, reduced lifespan of RBCs in circulation, or excessive bleeding, leading to a reduced amount of oxygen being transported by RBCs. Monitoring your hematocrit levels is essential for diagnosing and managing various blood-related disorders.

  • Total Leukocyte Count

  • A Total Leukocyte Count test measures the numbers of all types of leukocytes, namely neutrophil, lymphocyte, monocyte, eosinophil, and basophil, in your blood. Leukocytes or WBCs are an essential part of our immune system. These cells are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

  • Absolute Lymphocyte Count

  • An Absolute Lymphocyte Count test measures the total number of lymphocytes in the blood. Lymphocytes are a type of white blood cells that play an important role in your immune system and help your body fight disease and infection. There are two main types of lymphocytes:

    • T lymphocytes (T cells): T cells control your body’s immune system response and directly attack and kill infected cells and tumor cells.

    • B lymphocytes (B cells): B cells make antibodies. Antibodies are proteins that target viruses, bacteria, and other foreign pathogens.

    Lymphocytes help your immune system remember every antigen (a foreign substance) it comes in contact with. After an encounter, some lymphocytes turn into memory cells. When these memory cells run into an antigen again, they recognize it and quickly respond. It is also the reason why getting vaccinated helps prevent certain diseases.

  • Hb (Hemoglobin)

  • An Hb (Hemoglobin) test measures the concentration of hemoglobin protein in your blood. Hemoglobin is made up of iron and globulin proteins. It is an essential part of RBCs and is critical for oxygen transfer from the lungs to all body tissues. Most blood cells, including RBCs, are produced regularly in your bone marrow. The Hb test is a fundamental part of a complete blood count (CBC) and is used to monitor blood health, diagnose various blood disorders, and assess your response to treatments if needed.

  • Absolute Neutrophil Count

  • An Absolute Neutrophil Count test measures the percentage of neutrophils per microliter of blood. Neutrophils are a type of WBC and play an integral part in the body's immune system. They help fight off bacterial infections in the body by identifying and destroying foreign invaders, such as disease-causing microorganisms. 

  • Mean Corpuscular Hemoglobin

  • An MCH test measures the average amount of hemoglobin in a single red blood cell (RBC). Hemoglobin is an iron-containing protein in RBCs, and its major function is to transport oxygen from the lungs to all body parts. This test provides information about how much oxygen is being delivered to the body by a certain number of RBCs.

  • Absolute Basophil Count

  • An Absolute Basophil Count test measures the total number of basophils in the blood. Basophils are small, spherically-shaped cells that originate from bone marrow and make up almost 1% of the total white blood cells in the body. They attack a foreign substance and release proteins like histamine and heparin to destroy harmful substances, such as allergens, pathogens, or parasites. Histamine helps widen the blood vessels and make space for more immune cells to come to the site of infection or injury, whereas heparin acts as a blood-thinning agent and helps to avoid blood clotting at that site.

  • Differential Leukocyte Count

  • There are five types of WBCs: neutrophils, lymphocytes, monocytes, eosinophils, and basophils. A Differential Leukocyte Count test measures the percentage of each type of WBC in the blood. Leukocytes or WBCs are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

    This further contains

    • Differential Neutrophil Count
    • Differential Lymphocyte Count
    • Differential Monocyte Count
    • Differential Eosinophil Count
    • Differential Basophil Count
  • Red Blood Cell Count

  • A Red Blood Cell Count test measures the total number of red blood cells in your blood. RBCs are the most abundant cells in the blood with an average lifespan of 120 days. These cells are produced in the bone marrow and destroyed in the spleen or liver. Their primary function is to help carry oxygen from the lungs to different body parts. The normal range of RBC count can vary depending on age, gender, and the equipment and methods used for testing.

  • Mean Corpuscular Volume

  • A Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are uniform or vary significantly in size.

  • Mean Corpuscular Hemoglobin Concentration

  • An MCHC test measures the average amount of hemoglobin in a given volume of RBCs. MCHC is calculated by dividing the amount of hemoglobin by hematocrit (volume of blood made up of RBCs) and then multiplying it by 100. 

  • PDW

  • A PDW test reflects variability in platelet size, and is considered a marker of platelet function and activation (clot formation in case of an injury). This marker can give you additional information about your platelets and the cause of a high or low platelet count. Larger platelets are usually younger platelets that have been recently released from the bone marrow, while smaller platelets may be older and have been in circulation for a few days. Higher PDW values reflect a larger range of platelet size, which may result from increased activation, destruction and consumption of platelets.

  • Mean Platelet Volume

  • An MPV test measures the average size of the platelets in your blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop bleeding whenever there is an injury or trauma to a tissue or blood vessel by adhering and accumulating at the injury site, and by releasing chemical compounds that stimulate the gathering of more platelets. After these steps, a loose platelet plug is formed at the site of injury, and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or are not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • Absolute Eosinophil Count

  • An Absolute Eosinophil Count test measures the number of eosinophils in the blood and provides important information about the functioning of the immune system. Eosinophils originate from bone marrow and have a lifespan of 8-18 hours. These cells are involved in fighting certain types of infections and responding to allergic reactions in the body. The eosinophils have varied functions including the physiological role in organ formation, such as the development of post-gestational mammary glands. Other functions of these cells include movement to the inflammation areas, trapping substances, killing cells, and bactericidal and antiparasitic activities. They also help in the treatment of immediate allergic reactions and modulation of inflammatory responses. By measuring the number of eosinophils in the blood, this test provides important information about the functioning of the immune system.

  • Platelet Count

  • A Platelet Count test measures the average number of platelets in the blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop the bleeding, whenever there is an injury or trauma to a tissue or blood vessel, by adhering and accumulating at the injury site and releasing chemical compounds that stimulate the gathering of more platelets. A loose platelet plug is formed at the site of injury and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps, including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this step, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • Absolute Monocyte Count

  • An Absolute Monocyte Count test measures the total number of monocytes in the blood. Monocytes are a type of WBC that originate from bone marrow and travel to different tissues via the blood. Once they are inside the tissue, these cells get converted to macrophages (a type of cell that digest harmful substances). Monocytes are the second line of defense mechanism of the human body after neutrophils. These cells are also responsible for the removal of injured or dead cells, microorganisms, and other insoluble particles from the blood. 

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Serum Ferritin

A Serum Ferritin test measures the concentration of ferritin in the blood. Ferritin is a protein found in cells, particularly in the liver, spleen, and bone marrow, that stores iron in a soluble or nontoxic form. When the body needs iron for essential functions like producing red blood cells and carrying oxygen, it releases iron from ferritin into the blood.

A Serum Ferritin test provides valuable information about the body's iron storage levels. Low ferritin levels may indicate iron deficiency, a condition where the body lacks enough iron to function properly. In contrast, elevated ferritin levels can indicate iron overload, a condition known as hemochromatosis. Iron overload can lead to organ damage if not adequately managed, making early detection crucial.

A Serum Ferritin test is a critical tool for assessing iron status, diagnosing iron deficiency anemia, monitoring treatment progress, detecting other iron-related disorders, and maintaining overall health.

Know more about Serum Ferritin

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Hb HPLC (Hb Variants Estimation by HPLC)

An Hb HPLC (Hb Variants Estimation by HPLC) test is used to identify and quantify different types of hemoglobin in the blood to diagnose and monitor specific blood disorders. Different types of hemoglobin are Adult type (HbA2), Fetal type (HbF), Hemoglobin S (HbS), Hemoglobin C (HbC), and Hemoglobin E (HbE), etc.

Normal types of hemoglobin include:

  • Hemoglobin (Hgb) A: The most common type of hemoglobin in healthy adults
  • Hemoglobin (Hgb) F: Fetal hemoglobin, which is found in unborn babies and newborns. HgbF is replaced by HgbA shortly after birth.

A deranged level of HgbA or HgbF might indicate certain types of anemia.

Abnormal types of hemoglobin include:

  • Hemoglobin (Hgb) S: This type of hemoglobin is found in sickle cell anemia, an inherited disorder that causes the body to make stiff, sickle-shaped red blood cells. Sickle cells can get stuck in the blood vessels, causing severe pain, long-term infections, and other complications.
  • Hemoglobin (Hgb) C: This type of hemoglobin is associated with hemolytic anemia that develops when your red blood cells are destroyed more easily than normal red blood cells or have a shorter life span than normal red blood cells. 
  • Hemoglobin (Hgb) E: This type of hemoglobin is mainly found in people of Southeast Asian descent and may be associated with mild anemia or no symptoms. 
  • Hemoglobin (Hgb) D: Hb D disease (HbDD) is characterized by mild hemolytic anemia and mild to moderate splenomegaly. Hb D Punjab occurs with the most significant prevalence in Gujarat and Sikhs of Punjab.

Know more about Hb HPLC (Hb Variants Estimation by HPLC)

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