Overview of Coombs Test - Indirect
Why Get Tested
• To screen the recipient of a blood transfusion before the transfusion is done
• To screen the mother’s blood for antigens that can target the RBCs of the newborn
• For evaluation of hemolytic anemia
- No special preparation required
What Results of Coombs Test - Indirect mean?
Positive results for the Indirect Coombs test indicates that antibodies against one or more antigens being screened are present in the blood sample being tested. When tested positive in a pregnant woman, it indicates the presence of Rh antibody in the mother’s blood that may destroy the RBCs of the baby in some cases.