Overview of Estradiol
What is Estradiol?
Preparation for Estradiol
- No special preparation required
Why Get Tested for Estradiol?
To diagnose hypogonadism (production of fewer sex hormones) in females
To evaluate the cause of oligomenorrhea (Infrequent menstruation) and irregular menstruation in females
To evaluate the cause of feminization in males like gynecomastia (enlarged breasts)
To evaluate the cause of precocious (early) and delayed puberty in females
To evaluate the symptoms of menopause like abnormal vaginal bleeding
To monitor follicle development in case of infertility in women
To monitor treatment in case of hormone replacement therapy taken by postmenopausal women
To evaluate lack of secondary sexual features in males, lack of muscle development mass, delayed puberty
Understand more about Estradiol
Estradiol is a form of estrogen hormone which plays an important role in the function and development of reproductive organs and in the formation of secondary sex characteristics in females. It regulates the menstrual cycle in women along with progesterone. Other functions of Estrogen along with progesterone include the growth of breasts and uterus and help in maintaining a healthy pregnancy. Estrogen hormone is also found in men. It plays role in growth and metabolism in both males and females. In men, estradiol is produced in testicles while in pre-menopausal women it is produced in ovaries. In postmenopausal women, estradiol is converted to estrone. Estradiol is present in high levels in non-pregnant and pre-menopausal women. Depending upon the age of the women and her reproductive status the values of Estradiol varies. It is considered to be one of the good markers as regards to ovarian function.
At birth the levels of Estradiol are high but the levels fall within a few days and become minimal during early childhood. As the puberty approaches the levels of Estradiol rise. During the menstrual cycle, its levels vary depending upon which phase of the menstrual cycle is ongoing. During menopause, the levels of Estradiol falls as the production of ovaries decreases.
What Results of Estradiol mean?
High levels of Estradiol may indicate:
Puberty before time (Precocious Puberty) in girls
Ovarian Tumors in females
Tumors of adrenal glands in men and women
Gynecomastia (Enlarged breasts) in men
Delayed puberty in males
Hyperthyroidism in men and women
Cirrhosis in men and women
Low levels of Estradiol may indicate:
Hypogonadism in females (The abnormal function of ovaries)
Conditions in which female sexual characteristics are underdeveloped like Turner’s Syndrome
Patient Concerns about Estradiol
Frequently Asked Questions about Estradiol