Test Detail

Content created by

Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
Want to know more?
Read our Editorial Policy


You need to provide
Tissue Block
This test is for
Male, Female
Test Preparation
  1. Special Requirement --> Tissue block to be submitted for testing. Tissue block will be returned back post processing.


What is ALK By IHC & ROS - 1 By IHC?

ALK stands for the term anaplastic lymphoma receptor tyrosine kinase gene. This test detects particular rearrangements in the ALK gene present in cancer cells and tissue. The presence of these gene alterations makes it more likely that a person suffering from non-small cell lung cancer will respond well to treatments such as targeted drug therapy.

ROS-1 test is done for identifying c-ROS oncogene 1 (ROS1) gene rearrangements in patients suffering from late-stage, lung cancer, or adenocarcinomas that show negative results for negative for epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements. The ROS1 gene is a receptor tyrosine kinase, a cell surface receptor that has been shown not only to be a key regulator of normal cellular processes, but it also has a crucial role to play in the development and progression of many types of cancer, including lung cancer.

What does ALK By IHC & ROS - 1 By IHC Measure?

1. An ALK or ROS-1 mutation test is usually done after an individual has been diagnosed with non-small cell lung cancer, particularly adenocarcinoma.
2. These tests are also ordered in case of rare ALK or ROS-1 gene mutations that are not detected by routine testing which is only done in case of common mutations.



We at CORE Diagnostics are a renowned pathology testing laboratory & a premier institute in the country capable of providing varied diagnostic tests & facilities in the field of laboratory medicine and have established state-of-art testing facilities in Gurgaon. We are a Clinical laboratory focused on Next Generation Diagnostics for disease stratification and therapy selection. We are focused on bringing the most advanced testing techniques and expertise to India and aim to become the...
Know More

Available at Other Labs


Orders Delivered
Get the link to download App

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited


1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant


Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.