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    Information about Trihexyphenidyl/Benzhexol

    Trihexyphenidyl/benzhexol uses

    Trihexyphenidyl/Benzhexol is used in Parkinson's disease and drug induced abnormal movements.

    How trihexyphenidyl/benzhexol works

    Trihexyphenidyl/Benzhexol is an anticholinergic medication. It works by decreasing the activity of a chemical messenger (acetylcholine) in the brain. This improves muscle control and reduces stiffness in Parkinson's disease. It also improves movement disorder (restlessness, involuntary movements or muscle spasm) caused by certain other medicines.

    Common side effects of trihexyphenidyl/benzhexol

    Dryness in mouth, Nausea, Vomiting, Constipation, Blurred vision, Dizziness, Stomach upset, Headache, Difficulty in urination, Nervousness
    Content Details
    Written By
    Dr. Swati Mishra
    Reviewed By
    Dr. Shilpa Garcha
    MD (Pharmacology), MBBS
    Last updated on:
    16 Oct 2019 | 01:31 PM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Trihexyphenidyl/Benzhexol

    • Trihexyphenidyl/Benzhexol helps treat Parkinson's disease and drug-induced abnormal movements.
    • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
    • It may cause dry eyes. Avoid wearing contact lenses and inform your doctor if it bothers you.
    • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
    • Monitoring of intraocular pressure is required while taking this medicine, as an increase in eye pressure may cause blurry vision.
    • You may be asked for regular monitoring of hypotension,  kidney, liver, and cardiac disorder while taking this medicine. 
    • Inform your doctor if you suffer from  glaucoma or if you have trouble passing urine.
    • Do not stop taking Trihexyphenidyl/Benzhexol without talking  to your doctor first as that may cause worsening of symptoms.

    Frequently asked questions for Trihexyphenidyl/Benzhexol


    Q. Is Trihexyphenidyl/Benzhexol a narcotic? Can I get high after taking Trihexyphenidyl/Benzhexol?

    No, Trihexyphenidyl/Benzhexol is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.

    Q. Does Trihexyphenidyl/Benzhexol make you drowsy?

    Yes, Trihexyphenidyl/Benzhexol may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.

    Q. What happens if more than the recommended doses of Trihexyphenidyl/Benzhexol are taken?

    Taking more than the recommended doses of Trihexyphenidyl/Benzhexol may cause flushing of the skin, nausea, vomiting, dilated pupils, increased heartbeat, rapid respiration, fever, increase in blood pressure, and dryness of mouth, tongue and skin. A rash may appear on the face or upper trunk. You may also experience restlessness, confusion, hallucinations, paranoid and psychotic reactions, incoordination, delirium (a state of mental confusion and emotional disruption) and occasionally convulsions.

    Q. Does Trihexyphenidyl/Benzhexol cause weight gain?

    Yes, Trihexyphenidyl/Benzhexol may cause weight gain. If you are concerned about your weight gain, consult a dietician for diet plan, exercise regularly, and eat a healthy and nutritious diet.

    Content on this page was last updated on 16 October, 2019, by Dr. Varun Gupta (MD Pharmacology)