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    Tenofovir

    Information about Tenofovir

    Tenofovir uses

    Tenofovir is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.

    How tenofovir works

    Tenofovir prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.

    Common side effects of tenofovir

    Fatigue, Weakness, Headache, Nausea, Diarrhoea, Muscle pain, Pain, Dizziness, Depression

    Available Medicine for Tenofovir

    • ₹1438
      Cipla Ltd
      1 variant(s)
    • ₹472
      Zydus Cadila
      1 variant(s)
    • ₹1550
      Mylan Pharmaceuticals Pvt Ltd
      1 variant(s)
    • ₹1070
      Emcure Pharmaceuticals Ltd
      1 variant(s)
    • ₹1310
      Natco Pharma Ltd
      1 variant(s)
    • ₹440 to ₹1300
      Hetero Drugs Ltd
      2 variant(s)
    • ₹1428
      Wockhardt Ltd
      1 variant(s)
    • ₹2380
      Abbott
      1 variant(s)
    • ₹1379
      Abbott
      1 variant(s)
    • ₹479
      Torrent Pharmaceuticals Ltd
      1 variant(s)

    Expert advice for Tenofovir

    • Do not take tenofovir if you are already taking medicines that contain tenofovir in combination with other drugs.
    • Do not take tenofovir with other drugs that can potentially damage your kidneys; especially adefovir (used in treatment of hepatitis B).
    • Contact your doctor immediately if you notice symptoms: deep and rapid breathing, drowsiness, urge to vomit (nausea), vomiting, muscle pain or weakness, numb or cold feeling in your arms and legs, stomach pain, fast or uneven heart rate, or feeling very weak or tired. These might indicate development of a life-threatening side effect of tenofovir called lactic acidosis (excess lactic acid in blood). Lactic acidosis occurs more often in women, particularly if they are very overweight or are taking nucleoside antivirals for a long time.
    • Tenofovir may damage your kidneys (nephrotoxicity). Constant monitoring of kidney function (blood tests to assess the health of kidneys) is advised while on treatment with tenofovir.
    • Contact your doctor immediately if you have symptoms: persistent urge of vomit (nausea), upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (abnormal liver function causing yellowing of the skin or eyes). These might indicate development of severe liver damage.
    • Decreases in bone mineral density can happen while taking tenofovir.
    • Do consult your doctor before taking tenofovir if you are pregnant or planning to become pregnant.
    • Do not use tenofovir if you are breast-feeding.
    • Tenofovir may cause lipodystrophy (changes in body fat - build up or loss of body fat) especially in elderly patients with HIV. Physical examination of fat redistribution and monitoring of blood levels of lipids and sugar may be advised in elderly.
    • Discuss with your doctor about necessary precautions (practicing safer sex and making other life-style changes) to be taken to avoid spreading of HIV virus to others.

    Frequently asked questions for Tenofovir

    Tenofovir

    Q. Is tenofovir a NRTI?
    Yes. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs)
    Q. What is tenofovir/tenofovir disoproxil fumarate used for/ What does tenofovir treat?
    Tenofovir is an antiviral drug used in combination with other drugs in the treatment of human immunodeficiency virus (HIV) infections. It may also be used in very limited cases of long-term infections of liver caused by hepatitis B virus
    Q. Is Viraday safe/ effective?
    Viraday is a trade name for fixed-dose combination of drugs efavirenz, emtricitabine, and tenofovir. It is safe and effective if used at prescribed doses for the prescribed duration as advised by your doctor
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    Q. Is viraday the same as atripla?
    Yes. Viraday and atripla are trade names for fixed-dose combination of drugs efavirenz, emtricitabine, and tenofovir. They are used in the treatment of HIV
    Q. How does tenofovir work?
    Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). By the virtue of its structure that closely resembles the natural structure of viral DNA, tenofovir incorporates itself into the viral DNA. By doing so, it blocks the activity of an important viral enzyme reverse transcriptase which is involved in the replication of viral DNA, a process essential for survival of the virus
    Q. Does tenofovir cause hair loss?
    Hair loss is not a known side effect of tenofovir
    Q. Does tenofovir cause lipodystrophy?
    Tenofovir may cause lipodystrophy (build up or loss of body fat) especially in elderly patients with HIV. Physical examination of fat redistribution and monitoring of blood levels of lipids and sugar may be advised in elderly
    Q. How does tenofovir cause renal toxicity/renal failure?
    Tenofovir is predominantly excreted by the kidneys. The part of kidneys involved in its excretion is called the proximal tubule. Studies indicate that tenofovir accumulation in the proximal tubule due to interaction with other drugs (eg. ritonavir) or prolonged use is responsible for kidney damage (renal toxicity). The kidney damage may then progress to kidney failure
    Q. Does tenofovir cure hepatitis B/ Is viraday effective/does viraday work?
    Yes. Viraday is effective against human immunodeficiency virus (HIV) and some cases of hepatitis B. It is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

    Content on this page was last updated on 05 September, 2017, by Dr. Varun Gupta (MD Pharmacology)