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Metadoxine
INFORMATION ABOUT METADOXINE
Metadoxine Uses
Metadoxine is used in the treatment of cholestatic liver diseases, alcoholic fatty liver disease and Non-alcoholic fatty liver disease.
How Metadoxine works
Metadoxine is an antioxidant. It works by protecting the liver from harmful chemical substances (free radicals). It also works by increasing alcohol elimination from the blood and tissues, thus preventing liver damage.
Common side effects of Metadoxine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Upset stomach, Diarrhea
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
10 Apr 2025 | 04:43 AM (UTC)
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Expert advice for Metadoxine
  • It protects the liver cells from toxins and helps the liver to perform its normal functions.
  • Take it as per dose and duration suggested by your doctor.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • It protects the liver cells from toxins and helps the liver to perform its normal functions.
  • It should preferably be taken after meals. One of the doses should always be taken after your evening meal.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Do not take antacids that contain aluminum while you are taking Metadoxine as this decreases the amount of Metadoxine absorbed by your body.
  • Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.
Frequently asked questions for Metadoxine
Metadoxine belongs to a class of medicines known as hepatoprotective medicines which means that they protect the liver. It is used to treat chronic and acute alcohol intoxication. Metadoxine accelerates alcohol clearance from the blood and therefore, also helps in the treatment of fatty liver due to alcoholism.
Metadoxine works by increasing the rate of alcohol clearance from blood and tissues, which leads to faster recovery from alcohol intoxication. This in long term protects the liver from damage against harmful chemicals known as free radicals, thereby improving overall health of the liver.
Metadoxine may be taken with or without food as prescribed by the doctor. Take it in the dose and duration advised by the doctor. Swallow the tablet whole; do not crush, break or chew. The dose will depend on the condition you are being treated for and your total body weight. It is advised to follow your doctor’s instructions carefully to get maximum benefit of Metadoxine.
The most common side effects associated with Metadoxine include nausea, upset stomach and diarrhea. However, these effects are not observed in all patients. If you are worried about them or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea.
Metadoxine is not advised to be taken by pregnant and breastfeeding women. Consult your doctor before taking Metadoxine if you are planning to conceive, pregnant or breastfeeding to prevent harmful effects on the baby.