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MD (Microbiology), MBBS
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MD (Pharmacology), MBBS
Last updated on:
18 Jun 2019 | 06:52 PM (IST)
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Zymurine Tablet

Prescription Required

Overview

Zymurine Tablet side effects

Common
  • Nausea
  • Fungal infection
  • Bacterial infection
  • Viral infection
  • Decreased white blood cell count
  • Low blood platelets

How to use Zymurine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zymurine Tablet is to be taken with food.

How Zymurine Tablet works

Zymurine Tablet is an immunosuppressant. It reduces the action of body's own defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.

Zymurine Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Zymurine Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
CAUTION
Zymurine Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
It is not known whether Zymurine Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Zymurine Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zymurine Tablet may be needed. Please consult your doctor.
Use of Zymurine Tablet is not recommended in patients with serious kidney disease.
Liver
CAUTION
Zymurine Tablet should be used with caution in patients with liver disease. Dose adjustment of Zymurine Tablet may be needed. Please consult your doctor.
Use of Zymurine Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • Your doctor has prescribed Zymurine Tablet to stop the body from rejecting a transplanted organ (e.g. kidney, heart or liver).
  • Zymurine Tablet also relieves joint pain and inflammation in rheumatoid arthritis.
  • You may have to take additional medications along with Zymurine Tablet for better relief of symptoms.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Avoid contact with people who have cold, flu or other contagious illness. Notify your doctor if you have any signs of infection such as a fever or sore throat.

Interaction with Drugs

Taking Zymurine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lefsum, Lefunid
LIFE-THREATENING
SERIOUS
Brand(s): Topram, Rigapril, Ram
SERIOUS
Brand(s): Urinol, Zeric, Seloric
SERIOUS
Brand(s): Enatol, AB-Pril, Inopril
SERIOUS
SERIOUS

Patient Concerns

Questions Related to Zymurine

arrow
I have stop tablet for last six months for Rhematology , but today had a serious pain in left hand , what is tablets now ?
Dr. Vipul Aggarwal
Bone & Joint Specialist
u are not supposed to stop treatment all of a sudden if u are taking it for rheumatoid arthritis u can take tab etoshine 90 mg sosbetter get a follow up down its ur docotor
My joint of my fingers and toes become stiff and painful in the morning while wake up and also feelung mild pain in my heart. I have been diagonised rheumatoid arthritis.
Dr. Akshat Goel
Bone & Joint Specialist
Please refer to a RheumatologistApply Dynapar QPS spray and take Tab Zerodol-SP twice daily and Tab Saaz 500mg twice daily and Tab HCQS-200 once daily
arrow
Do you have any questions related to Zymurine Tablet?

FAQs

Q. What is Zymurine prescribed for? How does it work?

Zymurine is an immunosuppressant which means that it acts by suppressing the immune defence system of the body. Your immune defence system helps to protect you against infections. However, sometimes your immune defence system can become overactive and can cause illness. Zymurine is used in combination with other medicines to treat the conditions caused due to this abnormal activity of the immune system. It is used to prevent rejection of transplanted organs, like kidney, heart or liver. It is also used to treat chronic active hepatitis, severe rheumatoid arthritis, systemic lupus erythematosus (SLE), idiopathic thrombocytopenic purpura and acquired hemolytic anemia. It is also used to treat severe cases of specified skin diseases (pemphigus vulgaris, dermatomyositis, polyarteritis nodosa, pyoderma gangrenosa), especially when corticosteroids cannot be used.

Q. How long does Zymurine take to start working?

It may take about 3 to 12 weeks before you see any benefits. Continue the medication even if you do not notice any benefits. Talk to your doctor if you face any issues.

Q. What happens if I forget to take Zymurine?

If you miss a dose of Zymurine, take it as soon as you remember. However, skip the missed dose if it is time for your next dose. Do not take a double dose to compensate for the missed dose. inform your doctor if the dose is frequently missed.

Q. How long do I need to take azathioprine?

The duration varies from person to person as it is prescribed depending upon the patient’s medical condition.

Q. Is breastfeeding safe during azathioprine treatment?

No, breastfeeding should be avoided, while on azathioprine, since it may harm the baby and cause serious side effects.

Q. I have just started taking azathioprine. What are the long-term side effects? Is there anything I should be looking out for?

Being an immunosuppressant, azathioprine can increase the chances of severe infections, decrease in blood cell counts, and malignancy. You should inform your doctor immediately if you notice any infection or fever, unexpected bruising or bleeding, black tarry stools or blood in the urine or stools. Let your doctor know if you notice any new skin sore or lump, new marks on skin or any change in the marks which were previously present.

Q. Do I need any special tests while I am on azathioprine?

Azathioprine reduces the production of blood cells making you more vulnerable to infections and can sometimes affect the liver. These side effects can be monitored by regular blood tests. Therefore, during the first 8 weeks of the treatment your doctor may recommend weekly blood tests to monitor complete blood counts, including platelet counts. The frequency can later be reduced to monthly or at least once in 3 months time.

Q. Can azathioprine cause cancer?

Azathioprine may increase the chance of developing certain cancers like skin cancer, cancer of the lymph system (lymphoma), cancer of soft tissues (sarcomas), and cervical cancer. To prevent the risk of skin cancer, avoid prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen. Tell your doctor immediately if you notice any changes in your skin or any lumps or masses anywhere on your body.

Q. Can cyclosporine and azathioprine be taken together?

Yes, you can take cyclosporine and azathioprine together as they do not interfere with each other’s working. However, you must take the two medicines strictly as per your doctor’s advice.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.
  2. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.
  4. Azathioprine. Barnstaple, Devon: Actavis UK Limited; 2018. [Accessed 05 Feb. 2019] (online) Available from:External Link
  5. Azathioprine. San Diego, California: Prometheus Laboratories Inc.; 2014. [Accessed 06 Apr. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
  7. Azathioprine. Dartford, UK: Ennogen Pharma Ltd.; 2009 [revised 29 Jun. 2016]. [Accessed 17 Jun. 2019] (online) Available from:External Link
  8. Oxford Radcliffe Hospitals: NHS Trust. Azathioprine - General Information; 2012. [Accessed 17 Jun. 2019]. (online) Available from:External Link
Manufacturer/Marketer Address
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
A licensed pharmacy from your nearest location will deliver Zymurine Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹72.78
MRP90.97  Get 20% OFF
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4 tablets in 1 strip
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