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MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Zygem 1gm Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Zygem 1gm Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.

Zygem 1gm Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, hair loss and low blood platelets. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Side effects of Zygem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zygem

  • Nausea
  • Vomiting
  • Loss of appetite
  • Hair loss
  • Low blood platelets
  • Allergic reaction
  • Breathlessness
  • Decreased white blood cell count
  • Increased liver enzymes
  • Anemia (low number of red blood cells)
  • Flu-like symptoms
  • Blood in urine
  • Skin rash
  • Protein in urine

How to use Zygem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zygem Injection works

Zygem 1gm Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Safety Advice

Alcohol
UNSAFE
Zygem 1gm Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zygem 1gm Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Zygem 1gm Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Zygem 1gm Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Zygem 1gm Injection in patients with kidney disease. Please consult your doctor.
Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zygem 1gm Injection in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zygem 1gm Injection
₹3751.0/Injection
Gemtaz 1gm Injection
Sun Pharmaceutical Industries Ltd
₹4722.13/Injection
26% costlier
Gempower 1gm Injection
Khandelwal Laboratories Pvt Ltd
₹5000/Injection
33% costlier
Emcitaben 1gm Injection
RPG Life Sciences Ltd
₹6000/Injection
60% costlier
Citafine 1gm Injection
Emcure Pharmaceuticals Ltd
₹6132/Injection
63% costlier
Gemcite 1gm Injection
Eli Lilly and Company India Pvt Ltd
₹6200/Injection
65% costlier

Quick Tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Cytosine Analogue
Habit Forming
No

Patient Concerns

arrow
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
arrow
Do you have any questions related to Zygem 1gm Injection ?

FAQs

Q. Is Zygem 1gm Injection a vesicant/ anthracycline/ prodrug?

Zygem 1gm Injection is not a vesicant/ anthracycline/ prodrug

Q. Does Zygem 1gm Injection cause hair loss or abdominal pain?

Yes, Zygem 1gm Injection has hair loss and abdominal pain as side effects. Please consult your doctor immediately if you experience such side effects

Q. Is Zygem 1gm Injection a cytotoxic or chemotherapy agent?

Yes, Zygem 1gm Injection is a cytotoxic chemotherapy agent

Q. Does Zygem 1gm Injection work in pancreatic cancer?

Yes, Zygem 1gm Injection is used to treat pancreatic cancer.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1700-701.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 947-48.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 617-18.
  4. Gemcitabine hydrochloride. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2013 [revised 20 Jan. 2019] [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Drug.com. Gemcitabine Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
3751
MRP6700  44% OFF
1 Injection in 1 vial
SOLD OUT

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