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Zyalfa D 10 mg/0.5 mg Tablet



Zyalfa D 10 mg/0.5 mg Tablet is a combination of two medicines which work in different ways to treat men with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often. It is not used to prevent prostate cancer.

Zyalfa D 10 mg/0.5 mg Tablet should be taken at the same time each day. Take it as a whole – do not break, chew or crush them. Your doctor will prescribe the dose most suitable for you. To gain the most benefit and treat your symptoms effectively you should not miss doses, even if you feel well. It may take up to 4 weeks to notice an improvement in symptoms but keep taking them regularly. Tell your doctor if your symptoms do not improve after 4 weeks or if they get worse.

The most common side effects of this medicine include reduced sex drive, inability to get an erection (impotence) and tenderness or enlargement of your breasts. If these effects worry you or do not go away, call your doctor for advice. You may also feel dizzy or drowsy. These risks are higher when you first start taking this drug. Remember, your doctor has given you this medicine because the benefits are greater than the risks of the side effects.

Zyalfa D 10 mg/0.5 mg Tablet should not be taken by women or children. Before taking it, tell your doctor if you have low blood pressure or liver or kidney disease. This medicine may not be suitable. It can also affect, or be affected by, other drugs so let your doctor know all other medicines you are taking. You may be advised to wear a condom during sex and to have your blood pressure checked frequently. Talk to your healthcare team if you drink alcohol.

Uses of Zyalfa D Tablet

Side effects of Zyalfa D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zyalfa D

  • Impotence
  • Decreased libido
  • Breast pain
  • Ejaculation disorder
  • Dizziness
  • Headache

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Impotence and Ejaculation disorder
    Speak to your doctor as they may be able to change your medicine or offer other treatments that might help with the problem. Making healthy lifestyle changes and eating a healthy balanced diet can help. Lose weight if you are overweight. Exercise daily and try to reduce stress and anxiety. Avoid the use of alcohol, cigarettes or recreational drugs such as marijuana which can also affect sexual function. Counselling or psychotherapy can also be helpful.
  • Coping with Decreased libido
    If you experience this side effect, talk to your doctor. They may be able to reduce your dose or change your medication. In general, healthy lifestyle changes such as eating a healthy diet and keeping a healthy weight can make a big difference. Regular exercise can increase your stamina, lift your mood and boost your libido. Find ways of coping with stress such as meditation or relaxation techniques. Avoid smoking and drinking alcohol, as they can lower your sex drive.
  • Coping with Breast pain
    Use hot or cold compresses on your breasts. You could try some pain-relieving creams or gels. Wear bras which fit well. Wear a soft support bra when you sleep and a good sports bra when you are exercising. Avoid consuming caffeinated drinks as it can increase the discomfort. Limit your salt intake as it contributes to water retention which causes pain and swelling. Talk to your doctor because in many cases, it is possible to treat breast pain with over-the-counter medicines.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.

How to use Zyalfa D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyalfa D 10 mg/0.5 mg Tablet is to be taken with food.

How Zyalfa D Tablet works

Zyalfa D 10 mg/0.5 mg Tablet is a combination of two medicines: Alfuzosin and Dutasteride, which relieves the symptoms of benign prostatic hyperplasia. Alfuzosin is an alpha-blocker. It works by relaxing the muscle around the bladder exit and prostate gland so as to allow easy passage of urine. Dutasteride is a 5-alpha-reductase inhibitor which helps in shrinking the prostate gland by decreasing the level of the hormone which helps the prostate gland grow.

Safety Advice

Zyalfa D 10 mg/0.5 mg Tablet may cause excessive drowsiness with alcohol.
Zyalfa D 10 mg/0.5 mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Information regarding the use of Zyalfa D 10 mg/0.5 mg Tablet during breastfeeding is not available. Please consult your doctor.
Zyalfa D 10 mg/0.5 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Zyalfa D 10 mg/0.5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zyalfa D 10 mg/0.5 mg Tablet may not be needed in these patients. Please consult your doctor.
Zyalfa D 10 mg/0.5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zyalfa D 10 mg/0.5 mg Tablet may be needed. Please consult your doctor.
Use of Zyalfa D 10 mg/0.5 mg Tablet is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zyalfa D 10 mg/0.5 mg Tablet
Dutalfa Combipack
Dr Reddy's Laboratories Ltd
save 48%
Velfu D 10mg/0.5mg Tablet
Intas Pharmaceuticals Ltd
save 18%
Emzosin D 10mg/0.5mg Tablet
Emcure Pharmaceuticals Ltd
save 15%
Alfulix D 10mg/0.5mg Tablet
Elixir Life Care Pvt Ltd
save 10%
Flotral D Tablet
Sun Pharmaceutical Industries Ltd
1% costlier

Quick Tips

  • You have been prescribed Zyalfa D 10 mg/0.5 mg Tablet to relieve the symptoms of benign prostatic hyperplasia (BPH).
  • Take it approximately 30 minutes after the same meal each day.
  • Zyalfa D 10 mg/0.5 mg Tablet may cause dizziness or blurring of vision. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Zyalfa D 10 mg/0.5 mg Tablet.
  • It may cause difficulty achieving or maintaining an erection (impotence), decreased sex drive, and ejaculation disorders such as decreased amount of semen produced or decreased sperm count.
  • Do not donate blood for 6 months after taking the last dose of Zyalfa D 10 mg/0.5 mg Tablet.

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Sir, I am suffering from benign essential tremor, It is affecting in writting and holding cup in social gathering please suggest needful.
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Q. Does Zyalfa D shrink the prostate?

No, Zyalfa D does not shrink the size of the prostate. It belongs to the alpha-blocker class of medicines. It helps in relieving symptoms of an enlarged prostate. It works by relaxing the muscles of the bladder and prostate to allow urine to flow more easily.

Q. Can Zyalfa D cause erectile dysfunction?

No, Zyalfa D does not cause erectile dysfunction. On the contrary, it may help in improving any such condition. However, this medicine may cause painful erection (priapism) which does not go away. If priapism is not treated, you may not be able to get an erection in the future.

Q. When should I take Zyalfa D?

Zyalfa D should be taken after meals at the same time each day. Do not cut, crush or chew the medicine, but swallow it whole with water.

Q. Does Zyalfa D have any effect on the liver?

In very rare cases your liver may be affected and cause liver function abnormality. Hence, it would best to inform the doctor if you already have liver disease before starting the medication. The doctor will prescribe a lower dose of Zyalfa D once or twice daily.

Q. Can Zyalfa D be taken by old or elderly people?

Yes, it can be taken by elderly or old people, but they need to be careful. Regular monitoring is required in case the patient also has high blood pressure. Consult your doctor before taking Zyalfa D.

Q. Can Zyalfa D affect my eyes?

In rare cases, Zyalfa D may cause abnormal vision. But, it is important to know that this medicine may cause complications during surgery if you are to be operated for cataract. Hence, inform your doctor before surgery that you are taking Zyalfa D. Your doctor may perform surgery differently to prevent any complications.

Q. Can the use of Sildenafil or Vardenafil cause trouble when taken along with Zyalfa D?

Extreme care should be taken if you are taking Sildenafil or Vardenafil along with Zyalfa D. The combination may cause a significant decrease in blood pressure which can be serious. Therefore, inform your doctor if you are taking these medicines.

Q. What can patients do to help alleviate or prevent discomfort and side effects due to Zyalfa D?

Zyalfa D may lower your blood pressure especially when you suddenly stand up after lying down. You may feel dizzy or fainting and therefore you should get up slowly from bed or chair. This medicine may impair your reactions to certain conditions. Hence, avoid driving or hazardous activities until you know how this medicine will affect you.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. CiplaMed. Alfuzosin hydrochloride + Dutasteride. [Accessed 25 Apr. 2019] (online) Available from:External Link
  2. Alfuzosin HCl. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 2003 [revised May 2009]. [Accessed 31 Jan. 2019] (online) Available from:External Link
  3. Dutasteride. Research Triangle Park, North Carolina: GlaxoSmithKline; 2001 [revised Jun. 2008]. [Accessed 04 Apr. 2019] (online) Available from:External Link

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Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
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