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Composition for ZONEGRAN

Zonisamide(100 mg)

food interaction for ZONEGRAN

alcohol interaction for ZONEGRAN

pregnancy interaction for ZONEGRAN

lactation interaction for ZONEGRAN

It can be taken with or without food, but it is better to take Zonegran 100 mg tablet at a fixed time.
Zonegran 100 mg tablet may cause excessive drowsiness and calmness with alcohol.
Zonegran 100 mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Zonegran 100 mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Zonisamide(100 mg)


Zonegran 100 mg tablet is used in the treatment of epilepsy.

How it works

Zonegran 100 mg tablet controls seizures or fits by suppressing the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Agitation, Confusion, Decreased bicarbonate level in the blood, Depression, Double vision, Dizziness, Irritation, Loss of appetite, Memory impairement, Muscle coordination impaired, Sleepiness

Common Dosage for ZONEGRAN 100 MG TABLET

Patients taking ZONEGRAN 100 MG TABLET

  • 59%
    Twice A Day
  • 24%
    Once A Day
  • 8%
    Thrice A Day
  • 3%
    Thrice A week
  • 3%
    Alternate Day
  • 3%
    Four Times A Day


No substitutes found

Top Neurologists

  • Dr. Susant Kumar Bhuyan
    MBBS, MD, DM
  • Dr. Kapil Agarwal
    MBBS, MD, DM
  • Dr. Namit Gupta
    MBBS, MD, DM
  • Dr. Mayank Chawla
    MBBS, MD, DM
  • Dr. Isha Shukla
    MBBS, MD, DM

Expert advice for ZONEGRAN

  • If your child (<12 years old) has been prescribed with zonisamide, ask your doctor for necessary precautions, as they are at greater risk of reduced sweating, heat stroke, pneumonia and liver problems.
  • Dress lightly during hot climates or when exercising and check carefully for signs of decreased sweating or heat stroke.
  • Drink sufficient water while taking zonisamide to reduce the risk of kidney stones and heat strokes.
  • Do not stop using zonisamide suddenly, even if you feel fine as stopping suddenly may cause increased seizures. 
  • Seek immediate medical attention if you develop serious and sometimes fatal skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), as zonisamide (sulfa medicine) is known to cause such side effects.
  • Inform your doctor and seek medical advice if you develop any signs of suicidal thoughts or actions, depressed mood, anxious state, restlessness, irritable behavior or any unusual change in mood or behavior; high fever or long lasting fever.
  • Do not drive or operate machinery as zonisamide may cause dizziness, drowsiness, or vision changes.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for ZONEGRAN


Q.Is zonisamide a controlled substance/ addictive/ Narcotic/ gluten free/ generic?
Yes, Zonisamide is a controlled drug. It is not an addictive or narcotic drug. It is gluten free and a generic drug

Q.Is zonisamide used for weight loss or migraines?
Zonisamide is not used to treat weight loss or migraines

Q.Can I take ibuprofen/prednisone with zonisamide?
Yes, Ibuprofen or prednisone can be taken with zonisamide

Q.Does zonisamide cause weight gain/ kidney stones/hair loss/ weight loss/ diarrhea/ depression/ constipation/feeling high?
Zonisamide commonly does not cause all the above mentioned side effects except depression. Please consult your doctor if you develop such side effects.


Content on this page was last updated on 23 February, 2014, by Dr. Varun Gupta (MD Pharmacology)