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11 Nov 2019 | 01:58 PM (IST)
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Zita-Met Plus 1000mg/20mg Tablet


Overview

Introduction

Zita-Met Plus 1000mg/20mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.

Zita-Met Plus 1000mg/20mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Uses of Zita-Met Plus Tablet ER

Zita-Met Plus Tablet ER side effects

Common
  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach upset
  • Headache
  • Nasal congestion
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Zita-Met Plus Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zita-Met Plus 1000mg/20mg Tablet is to be taken with food.
Zita-Met Plus 1000mg/20mg Tablet may cause stomach upset if taken on empty stomach.

How Zita-Met Plus Tablet ER works

Zita-Met Plus 1000mg/20mg Tablet is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Zita-Met Plus Tablet ER related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zita-Met Plus 1000mg/20mg Tablet
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Zita-Met Plus 1000mg/20mg Tablet during pregnancy is not available. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Information regarding the use of Zita-Met Plus 1000mg/20mg Tablet during lactation is not available. Please consult your doctor.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Zita-Met Plus 1000mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zita-Met Plus 1000mg/20mg Tablet may be needed. Please consult your doctor.
Use of Zita-Met Plus 1000mg/20mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Zita-Met Plus 1000mg/20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zita-Met Plus 1000mg/20mg Tablet may be needed. Please consult your doctor.
Zita-Met Plus 1000mg/20mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

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Expert Advice

  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Zita-Met Plus 1000mg/20mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Patient Concerns

Questions Related to Zita-Met Plus

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Type 2 Diabetes for the part 4 yrs. Taking one dose of Galvus met 250/25mg after night meal. Following exercise and diet. The sugar level is 170 to 190. Do I need to take more medicines or Is this enough
Dr. Satish Kumar Jyoti
Diabetes Specialist
Is this your fasting blood sugar or pp
I am having Type-2 Diabetes. I have consulted with Dr. Vineet PATIENT He has advised me to take Galvus met along with Evion 400 capsule. My current Blood Sugar level is between 120 to 130(Fasting). Please suggest me further on medicine & other things if any
Dr. Sanjay Bhatt
Diabetes Specialist
It is easy to maintain sugar levels.You should have dedication to do regular exercise and maintain your calories intake which your diabetic educator have be told.As only medicine can't help for long time.secondly you you take proper dose of medicine which doctor has adjusted for you as per your reports.thirdly time visit to doctor and do all routine investigations.
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Do you have any questions related to Zita-Met Plus 1000mg/20mg Tablet?

User Feedback


FAQs

Q. What are the instructions for the storage and disposal of Zita-Met Plus?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Zita-Met Plus?

Zita-Met Plus is a combination of two medicines: Metformin and Teneligliptin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Teneligliptin inhibits the enzyme DP4 inhibitor and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Zita-Met Plus?

The use of Zita-Met Plus is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious, but rare side effect like lactic acidosis. On long-term use it can also lead to vitamin B12 deficiency.

Q. Are there any specific conditions in which Zita-Met Plus should not be taken?

The use of Zita-Met Plus should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Zita-Met Plus?

No, it is not safe to take Zita-Met Plus along with alcohol. It can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or hepatic impairment.

Q. Can the use of Zita-Met Plus cause hypoglycemia?

The use of Zita-Met Plus does not usually cause hypoglycemia (low blood sugar level). However, hypoglycemia may occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry glucose tablets, honey or fruit juice with you.

Q. Can the use of Zita-Met Plus lead to Vitamin B12 deficiency?

Yes, the use of Zita-Met Plus can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
A licensed pharmacy from your nearest location will deliver Zita-Met Plus 1000mg/20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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