Zilast 50mg Tablet

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Ipca Laboratories Ltd

Composition for Zilast 50mg Tablet

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Primarily used for

95
₹9.5/Tablet
10 tablets in 1 strip
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Medicine Overview of Zilast Tablet

uses

Uses of Zilast Tablet

Zilast 50mg Tablet is used in the treatment of intermittent claudication
It helps in reducing the symptoms of intermittent claudication like pain, cramping, numbness, or weakness in the legs that occurs on walking.
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Side effects of Zilast Tablet

Common

Headache, Palpitations, Abnormal stool, Diarrhoea, Dizziness, Chest pain, Loss of appetite, Bleeding, Rash.

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How to use Zilast Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Zilast 50mg Tablet empty stomach (1 hour before food or 2 hours after food).

How Zilast Tablet works

Zilast 50mg tablet widens the blood vessels and decreases the stickiness of the platelets which increases blood flow to the lower limbs.

In Depth Information on Zilast Tablet

Expert advice for Zilast Tablet

  • Take cilostazol tablet 1-2 hours before or after meals. minutes before breakfast and the evening meal.
  • Do not drive or use machinery that required you to be alert because you may feel sleepy or dizzy while being treated with cilostazol.
  • Do not take cilostazol, if you have congestive heart failure. Cilostazol can make this condition worse.
  • It may take up to 12 weeks of using cilostazol before your symptoms improve. For best results, keep using the medication as directed.
  • Consult your doctor, if your symptoms do not improve after 4 weeks of treatment.
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Warnings
Special precautions for Zilast 50mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Zilast 50mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Zilast 50mg Tablet is probably usafe to use during lactation
. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
Zilast 50mg Tablet may make you feel dizzy, sleepy, tired, o
r decrease alertness. If this happens, do not drive.
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Kidney
Zilast 50mg Tablet should be used with caution in patients w
ith severe kidney disease. Dose adjustment of Zilast 50mg Tablet may be needed. Please consult your doctor.
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Liver
CAUTION
Zilast 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zilast 50mg Tablet may be needed. Please consult your doctor.

Use of Zilast 50mg Tablet is not recommended in patients with moderate and severe liver disease as the information available in these patients is limited.
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Severely interacts with other drugs like
Flutis 150mg Tablet, Onecan 400mg Tablet, Onitraz 100mg Capsule, AF 150mg Tablet DT

Missed Dosageuses

If you miss a dose of Cilostazol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Zilast 50mg Tablet

Frequently asked questions for Cilostazol

Zilast is used as a maintenance therapy for Raynaud's phenomenon in patients with systemic sclerosis. Raynaud's phenomenon is characterized by spasm of blood vessels of extremities causing pale to blue to red sequence of color changes of fingers mainly after exposure to cold. Zilast is helpful in this condition because of its vasodilating properties.
Zilast is not used for the treatment of erectile dysfunction. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
Use of Zilast is contraindicated in patients with severe renal disease because its metabolite levels are increased in these patients and can cause harmful effects. It can be used safely in patients with mild to moderate renal disease.
Peripheral vascular disease is associated with intermittent claudication which causes pain, cramping, numbness, or weakness in the legs while walking. This occurs due to blockage of arteries and insufficient blood flow to legs. Zilast increases blood flow and reduces the symptoms of intermittent claudication by widening the arteries and keeping the blood thin (does not allow platelets to stick together and form clots).
Q. Is it advisable to take Zilast with clarithromycin?
Clarithromycin can increase the level or effect of Zilast by blocking its breakdown (inhibits metabolism). The dose of Zilast may need to be adjusted if you have to take clarithromycin or other similar antibiotics like erythromycin along with.
Zilast, when used with aspirin and clopidogrel, was found to be superior compared to aspirin and clopidogrel dual combination in preventing coronary artery restenosis or in-stent thrombosis in patients who underwent percutaneous coronary intervention without increasing the risk of bleeding. However, this is not an approved use and these benefits were seen in some clinical studies.
Zilast can prevent new episodes of stroke without increasing the risk of bleeding in patients who once had an episode of ischaemic stroke. It is also seen to be effective for primary prevention of stroke in patients with peripheral artery disease. However, these are not approved uses and the benefits were seen in some clinical studies.
Zilast decreases the muscle pain or cramps that occur during exercise in patients with intermittent claudication. Zilast can improve exercise capacity as judged by changes in maximal walking distance and pain-free walking distance.
Zilast is contraindicated in patients with blood, and clotting disorders, heart failure or active pathologic bleeding like bleeding peptic ulcer and intracranial bleeding and known or suspected hypersensitivity to Zilast or any of its components.
Zilast should be stopped at least five days before surgery if the antiplatelet effect is not needed during the surgery. Due to reversible antiplatelet action and short half-life (11-13 h) of Zilast, the risk of surgical bleeding is less and regional anesthesia can be safely administered if it is stopped at least 72 h prior to surgery. However, Zilast should be stopped only after consulting your doctor and the surgeon.
Q. Can I take Zilast with sildenafil?
Zilast can be taken with sildenafil. There are no reported drug interactions or harmful effects when Zilast is taken along with sildenafil.
Zilast is to be taken 30 minutes before breakfast or evening meal as food increases the absorption of Zilast causing an increased incidence of side-effects.
Q. Can I take Zilast with warfarin?
Zilast, when taken with warfarin, can increase the risk of bleeding. So they should be used very cautiously and a regular monitoring by your doctor is advisable to decrease the risk of bleeding.
Zilast is not useful for the management of varicose veins. These are enlarged tortuous veins mainly of the lower limbs. These are treated with compression stockings, sclerotherapy (injecting some substances for closing these veins) or some surgical procedures.
Zilast, when taken with aspirin, is seen to improve long-term outcomes in patients undergoing percutaneous coronary angioplasty. However, there can be an increased risk of bleeding as both inhibit platelet aggregation and make blood thin. If you are taking Zilast with aspirin, you should be monitored very closely by your doctor.
Zilast for RESTenosis (CREST) clinical trial aimed to evaluate the efficacy of Zilast in inhibiting restenosis after stent implantation. The results showed a significant reduction in the occurrence of restenosis with the use of Zilast over the standard therapy after coronary stenting.
Q. Can I take Zilast with ticagrelor?
Zilast and ticagrelor, when used together, can increase the effects of each other by inhibiting clotting of blood and increasing the risk of bleeding. Avoid taking them together or you should be monitored very closely by your doctor.
Animal studies demonstrate the beneficial role of Zilast for the treatment of neuropathy. However, human studies do not show any beneficial role of Zilast in treating neuropathy.
Zilast is safe if used at prescribed doses for the prescribed duration as advised by your doctor. However, there are some very common side effects that you can experience at therapeutic doses which include a headache, abnormal stool, and diarrhea.
Q. Can I take Zilast with clopidogrel?
Zilast, when taken with clopidogrel, is seen to improve long-term outcomes in patients undergoing percutaneous coronary angioplasty. However, there can be an increased risk of bleeding as both inhibit platelet aggregation and make blood thin. If you are taking Zilast with clopidogrel, you should be monitored very closely by your doctor.
Zilast is not useful for arterial hypertension. It is used in the management of intermittent claudication associated with peripheral artery disease.
Do not stop Zilast unless advised by your doctor. Continue to take Zilast even if you feel better. Stop taking Zilast only if you experience easy bruising, bleeding, fever or a sore throat and immediately inform your doctor.
Q. Can I take Zilast with omeprazole?
Omeprazole can increase the level or effect of Zilast by blocking its breakdown (inhibits metabolism). Avoid using them together. An alternative medicine should be preferred.
Q. Can I use Zilast with atorvastatin?
Zilast can be taken with atorvastatin. No harmful effects or drug interactions have been seen or reported when Zilast is taken along with atorvastatin.
Zilast can be used in place of aspirin in patients who have an allergy to a spirin.
Q. Is it advisable to take Zilast with acenocoumarol?
Zilast, when taken with acenocoumarol, can increase the risk of bleeding. So they should be used very cautiously and a regular monitoring by your doctor is advisable to decrease the risk of bleeding.
There is no evidence at present which recommends the use of Zilast in the routine therapy of venous insufficiency.
Zilast is not useful in lowering the blood sugar levels in patients with diabetes. However, as seen in some clinical studies, it may help in relieving the symptoms of intermittent claudication (pain, cramping, numbness, or weakness in the legs on walking) seen in some patients with diabetes.
Zilast can increase the patient's heart rate, affect the heart rhythm and there is clinical evidence that it can increase mortality in patients with heart failure. So, Zilast is contraindicated in these patients.
Zilast is not an anticoagulant. It is a vasodilator with an anti-platelet aggregatory effect. It works by preventing platelets (blood cells) from sticking together and widens the blood vessels of the legs. This increases the blood flow in the peripheries.
No, Zilast is not a statin. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
No, Zilast is not a blood thinner. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
No, Zilast is not a beta blocker. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
Q. Is Zilast a better choice for the treatment of intermittent claudication compared to pentoxifylline?
Zilast is seen to be much better than pentoxifylline for increasing walking distances in patients with intermittent claudication but is associated with increased rates of side effects like a headache, palpitations, and diarrhea.
Zilast is not a controlled substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, Zilast is not a narcotic substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, Zilast is not an anticonception medicine. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
No, Zilast is not an antibiotic. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
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