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PhD (Pharmacology), PGDPRA
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MD (Pharmacology), MBBS
Last updated on:
28 May 2019 | 06:09 PM (IST)
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Zextil CL 200 mg/125 mg Tablet


Overview

Uses of Zextil CL Tablet

Zextil CL Tablet side effects

Common
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache

How to use Zextil CL Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zextil CL 200 mg/125 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zextil CL Tablet works

Zextil CL 200 mg/125 mg Tablet is a combination of two medicines: Cefpodoxime Proxetil and Clavulanic Acid. Cefpodoxime Proxetil is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefpodoxime Proxetil against bacteria.

Zextil CL Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
PROBABLY SAFE
Zextil CL 200 mg/125 mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.
Lactation
SAFE
Zextil CL 200 mg/125 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Zextil CL 200 mg/125 mg Tablet may cause side effects such as allergic reactions, dizziness or fits that may make you unfit to drive.
Kidney
Zextil CL 200 mg/125 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zextil CL 200 mg/125 mg Tablet may be needed. Please consult your doctor.
Liver
There is limited information available on the use of Zextil CL 200 mg/125 mg Tablet in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Zextil CL 200 mg/125 mg Tablet
₹26/Tablet
₹32.67/Tablet
26% costlier
Cefpo CV 200mg/125mg Tablet
Finecure Pharmaceuticals Ltd.
₹25/Tablet
save 4%
Cepodem XP 325 Tablet
Sun Pharmaceutical Industries Ltd
₹32.5/Tablet
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₹31.39/Tablet
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Swich CV 325 Tablet
Alkem Laboratories Ltd
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Expert Advice

  • You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. 
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect. Taking probiotics along with Zextil CL 200 mg/125 mg Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Take it with food and plenty of fluids to avoid an upset stomach.
  • Stop taking Zextil CL 200 mg/125 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Patient Concerns

Questions Related to Zextil CL

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I have diabetes, and I'm taking Glycomet for the same. I was recently hospitalised with a lower respiratory tract infection. The antibiotics I was prescribed gave me diarrhoea. Since the antibiotics course is now over, the doctor has now asked me to take Econorm (twice a day) and Sibofix 400 MG (twice a day). My question is whether I can avoid taking Sibofix, because I am afraid my diarrhoea will restart because Sibofix is an antibiotic. Currently my only problems are lack of appetite and a bloated sensation in my stomach.
Dr. Sanjay Bhatt
Diabetes Specialist
Do proper antibiotics course
I have diabetes, and I'm taking Glycomet for the same. I was recently hospitalised with a lower respiratory tract infection. The antibiotics I was prescribed gave me diarrhoea. Since the antibiotics course is now over, the doctor has now asked me to take Econorm (twice a day) and Sibofix 400 MG (twice a day). My question is whether I can avoid taking Sibofix, because I am afraid my diarrhoea will restart because Sibofix is an antibiotic. Currently my only problems are lack of appetite and a bloated sensation in my stomach.
Dr. Shikha Mishra
Dietician
For medicine related query please consult doctor
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Do you have any questions related to Zextil CL 200 mg/125 mg Tablet?

FAQs

Q. Can the use of Zextil CL cause diarrhea?

Yes, the use of Zextil CL can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Q. How long does Zextil CL takes to work?

Usually, Zextil CL starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Q. What if I don't get better after using Zextil CL?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Q. Can I stop taking Zextil CL when I feel better?

No, do not stop taking Zextil CL and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. What is Zextil CL?

Zextil CL is a combination of two medicines: Cefpodoxime and Clavulanic acid. This medication is used to treat bacterial infection. This medication works by killing the harmful bacteria that cause infection.

Q. Can the use of Zextil CL cause any serious side effects?

Zextil CL may cause serious side effects in very few patients (less than 1 in 1,000). Inform the doctor straight away if you get bloody diarrhea, yellowing of the eyes and skin, bruising or skin discoloration, shortness of breath, widespread rash, skin peeling and fever. All of these reactions needs urgent medical attention.

Q. Can I stop taking Zextil CL when my symptoms are relieved?

No, do not stop taking Zextil CL and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. Can Zextil CL cause allergic reaction?

Yes, Zextil CL can cause allergic reaction and is considered to be harmful patients with known allergy to a group of antibiotics called Cephalosporins. Get emergency medical help if you notice any of the signs of an allergic reaction: hives; difficulty in breathing; swelling of your face, lips, tongue or throat.

Q. Are there any specific contraindications associated with the use of Zextil CL?

The use of Zextil CL is considered to be harmful for patients with known allergy to penicillins or any other excipients present in this medicine. This medicine should not be used in patients with previous history of liver damage associated with Zextil CL.

Q. Can I take oral contraceptive pills while taking Zextil CL?

No, Zextil CL can make birth control pills less effective. So, ask your doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Zextil CL can increase the risks of side effects. Zextil CL takes time to show its full effect and treat your infection. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.

Q. What is the recommended storage condition for Zextil CL?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Cefpodoxime + Clavulanic Acid. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Das S, Fegade T. A Randomized, Open Label, Prospective, Comparative Study Evaluating the Efficacy and Safety of Fixed Dose Combination of Cefpodoxime 200 Mg + Clavulanic Acid 125 Mg Vs Cefpodoxime 200 Mg in Acute Bacterial Sinusitis. Indian Medical Gazette. 2015:225-31. [Accessed 09 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
A licensed pharmacy from your nearest location will deliver Zextil CL 200 mg/125 mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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