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17 Jul 2019 | 03:13 PM (IST)
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Zetaglim M 2mg Tablet


Overview

Introduction

Zetaglim M 2mg Tablet is used in the treatment of type 2 diabetes mellitus.

Zetaglim M 2mg Tablet is a combination of two medicines that effectively controls blood sugar levels when a single medication is not effective. It should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid the side effects like nausea and stomach upset.

Uses of Zetaglim M Tablet

Side effects of Zetaglim M Tablet

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Zetaglim M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zetaglim M 2mg Tablet is to be taken with food.

How Zetaglim M Tablet works

Zetaglim M 2mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zetaglim M 2mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Zetaglim M 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Zetaglim M 2mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Zetaglim M 2mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zetaglim M 2mg Tablet may be needed. Please consult your doctor.
Use of Zetaglim M 2mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Zetaglim M 2mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zetaglim M 2mg Tablet may be needed. Please consult your doctor.
Zetaglim M 2mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

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For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zetaglim M 2mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

arrow
Hi Doctor I have Type 2 diabetes, at present i m taking istamet 50/1000 mg, kindly advise if my medicine can be stopped
Dr. Shikha Mishra
Dietician
Please consult doctor regarding this issue
I am paitaint od type 2 diabetes. Now a days my fasting sugar at every morning comes near 180 In spite of i getting regular medicine for the same. Medicine are as following. 1. Amarley 2mg at morning. 2. Tab. Jalra M 1000/50 after meal. (BD) I m also a patient of BP and had gone through the Angioplasty
Dr. Sanjay Bhatt
Diabetes Specialist
Need to change some medicine .plz visit diabetologist near by or our clinic PNL ADVANCED HEALTH AND WELLNESS CLINIC"GURGAON 9XXXXXX
arrow
Do you have any questions related to Zetaglim M 2mg Tablet ?

User Feedback


FAQs

Q. What are the recommended storage conditions for Zetaglim M?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Zetaglim M lead to lactic acidosis?

Yes, the use of Zetaglim M can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Zetaglim M and consult your doctor immediately.

Q. What is Zetaglim M?

Zetaglim M is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Zetaglim M?

The use of Zetaglim M is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Can the use of Zetaglim M lead to Vitamin B12 deficiency?

Yes, the use of Zetaglim M can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Can the use of Zetaglim M cause hypoglycemia?

Yes, the use of Zetaglim M can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Is it safe to take alcohol while I am also taking Zetaglim M?

No, it is not safe to take Zetaglim M along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride + Metformin. Karachi, Pakistan: Sanofi-Aventis Pakistan Ltd. [Accessed 23 Jan. 2019] (online) Available from:External Link
  2. Metformin Hydrochloride Prolonged Release & Glimepiride Tablets I.P. Ankleshwar: Sanofi India Limited; 2018. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Elinor Pharmaceuticals (P)Ltd., #2-4-602, Road No 9/A, Beside Andhra Bank, New Nagole Colony, Nagole, Hyderabad - 500 035, Andhra Pradesh, India.
A licensed pharmacy from your nearest location will deliver Zetaglim M 2mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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