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Zavedos 5mg Injection
Prescription Required
Product introduction
Zavedos 5mg Injection is used in the treatment of some kinds of blood cancer (leukemia). It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Zavedos 5mg Injection is given as an injection under the supervision of a doctor, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells in your blood(decrease red blood and white blood cells), thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Zavedos 5mg Injection is given as an injection under the supervision of a doctor, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells in your blood(decrease red blood and white blood cells), thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Zavedos Injection
- Blood cancer (Acute lymphocytic leukemia)
Benefits of Zavedos Injection
In Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Zavedos 5mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Zavedos Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zavedos
- Vomiting
- Nausea
- Infection
- Hair loss
- Fever
- Increased liver enzymes
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Stomatitis (Inflammation of the mouth)
- Bleeding
- Myelosuppression
- Seizure
How to use Zavedos Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zavedos Injection works
Zavedos 5mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zavedos 5mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Zavedos 5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Zavedos 5mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Zavedos 5mg Injection may cause side effects which could affect your ability to drive.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.
Kidney
CAUTION
Zavedos 5mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Zavedos 5mg Injection may be needed. Please consult your doctor.
Get kidney function tests done before the start of this medicine.
Get kidney function tests done before the start of this medicine.
Liver
CAUTION
Zavedos 5mg Injection should be used with caution in patients with liver disease. Dose adjustment of Zavedos 5mg Injection may be needed. Please consult your doctor.
Get liver function tests done before the start of this medicine.
Get liver function tests done before the start of this medicine.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Zavedos 5mg Injection is given as an injection under the supervision of a doctor only.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood uric level, liver function, blood cell count in your blood.
- You may also be checked for heart functioning timely while on the treatment with this medicine.
Fact Box
Chemical Class
Anthracycline Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others
Patient concerns
User feedback
What are you using Zavedos Injection for?
Blood cancer *
100%
*Blood cancer (Acute lymphocytic leukemia)
How much was the improvement?
Excellent
67%
Average
33%
FAQs
Q. Is Zavedos 5mg Injection a vesicant?
Zavedos 5mg Injection can cause inflammation of the vein in which it is administered; and irritation and ulceration of surrounding tissue, if leakage occurs at the site of intravenous administration.
Q. What is Zavedos 5mg Injection used for?
Zavedos 5mg Injection is used in the treatment of acute myeloid leukaemia (a type of cancer of the white blood cells) in combination with other medications and breast cancer in advance stage after failure with other medications.
Q. How does Zavedos 5mg Injection work?
Zavedos 5mg Injection acts by inhibiting the growth of cancer cells.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 686-87.
- Idarubicin hydrochloride. Pfizer Limited: Sandwich, Kent: 2002. [revised Aug. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
- Idarubicin. New York, New York: Pharmacia & Upjohn Company; 2014. [Accessed on 27 Mar. 2019] (online) Available from:
Marketer details
Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: India
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