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Unicarb 150 Injection


Overview

Introduction

Unicarb 150 Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells.

Unicarb 150 Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Unicarb Injection

Side effects of Unicarb Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Unicarb

  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Fatigue
  • Low blood platelets
  • Increased liver enzymes
  • Decreased white blood cell count (neutrophils)
  • Stomatitis (Inflammation of the mouth)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Diarrhea

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Anemia (low number of red blood cells)
    Making some simple lifestyle changes can raise your red blood cell count. Reduce the amount of alcohol you drink, eat a well-balanced healthy diet and take regular exercise. Physical activities make your body need more oxygen and this stimulates the production of red blood cells. There are some vitamins which are important such as vitamin B-12, vitamin B-9, vitamin C and Vitamin A. Also, some minerals such as iron (especially) and copper. Aim for foods which contain higher quantities of these vitamins and minerals or ask your doctor for supplements. Make sure to consult your doctor for complete evaluation and treatment of anemia.
  • Coping with Low blood platelets
    You will need a blood test to find out if your blood platelet level is low. If this medicine is causing your platelet levels to drop, your doctor may suggest an alternative medicine. There are also medicines that can boost your blood platelet level. Consider asking your doctor about this. A low platelet count can put you at risk for bleeding. Try to be careful when doing activities that might cause an injury or a cut as it may take longer to stop bleeding.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.
  • Coping with Decreased white blood cell count (neutrophils)
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.

How to use Unicarb Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Unicarb Injection works

Unicarb 150 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Unicarb 150 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Unicarb 150 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Unicarb 150 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Unicarb 150 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Unicarb 150 Injection should be used with caution in patients with kidney disease. Dose adjustment of Unicarb 150 Injection may be needed. Please consult your doctor.
Use of Unicarb 150 Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Liver
SAFE IF PRESCRIBED
Unicarb 150 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Unicarb 150 Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Unicarb Injection?

If you miss a dose of Unicarb 150 Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Unicarb 150 Injection
₹99.0/ml of Injection
₹53.32/ml of Injection
save 46%
Womastin 150mg Injection
Khandelwal Laboratories Pvt Ltd
₹78.33/ml of Injection
save 21%
Carbokem Novo 150mg Injection
Alkem Laboratories Ltd
₹913.66/Injection
823% costlier
Carbopa 150mg Injection
Intas Pharmaceuticals Ltd
₹1175/Injection
1087% costlier
Biocarb 150mg Injection
Biochem Pharmaceutical Industries
₹1386/Injection
1300% costlier

Quick Tips

  • It is given as an injection into the veins under the supervision of a doctor.

Fact Box

Chemical Class
Platinum Analogs
Habit Forming
No

Patient Concerns

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What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
I seem to have lung cancer , becoz all the symptoms are same as lung cancer. I test my blood, they suggests me that it is highly probable to lung cancer. Sir what can i do now. This is in preliminary stage
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Do you think that lung cancer is diagnosed from blood
arrow
Do you have any questions related to Unicarb 150 Injection ?

FAQs

Q. Is Unicarb cell cycle specific?

No, Unicarb is not a cell cycle specific anticancer medication

Q. Is Unicarb FDA approved?

Yes Unicarb is an FDA approved drug

Q. Is it a platinum based drug?

Yes carboplatin is a platinum based drug and is effectively used in combination with other drug

Q. Does Unicarb cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?

Yes Unicarb is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Unicarb may cause leukemia if it is used for a long duration.

Q. Is Unicarb a generic?

Yes, Unicarb is a generic platinum-based compound

Q. Is Unicarb vesicant/cardio-toxic/ anthracycline?

No Unicarb is not cardio-toxic/ anthracycline/vesicant

Q. Is Unicarb used for breast cancer?

It is used to treat advanced stage breast cancer

Q. Is Unicarb available in pill form?

No Unicarb is not available in pill form

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1689.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 944.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 205-207.
  4. U.S. National Library of Medicine. Carboplatin. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Carboplatin. Maidenhead: Hospira UK Limited; 20 Jul. 2005 [revised Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Country of Origin: India
A licensed vendor partner from your nearest location will deliver Unicarb 150 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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