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Trupin 25 mg Tablet


Overview

Introduction of Trupin Tablet

Trupin 25 mg Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorder.

Trupin 25 mg Tablet works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should strictly be avoided as alcohol interacts with this medicine to cause serious health issues.

Uses of Trupin Tablet

Trupin Tablet side effects

Common
  • Dryness in mouth
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation

How to use Trupin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trupin 25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Trupin Tablet works

Trupin 25 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Trupin Tablet related warnings

Alcohol
UNSAFE
Trupin 25 mg Tablet may cause excessive drowsiness with alcohol
Pregnancy
CONSULT YOUR DOCTOR
Trupin 25 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Trupin 25 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Trupin 25 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Trupin 25 mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Trupin 25 mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Trupin Tablet?

If you miss a dose of Trupin 25 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Trupin 25 mg Tablet
₹3/Tablet
Dothip 25mg Tablet
Micro Labs Ltd
₹4.9/Tablet
63% costlier
₹8.1/Tablet
170% costlier
Dozep 25mg Tablet
Talent India
₹3.85/Tablet
28% costlier
DO RE ME 25mg Tablet
Intas Pharmaceuticals Ltd
₹3.75/Tablet
25% costlier
Dotin 25mg Tablet
Tas Med India Pvt Ltd
₹3.95/Tablet
32% costlier

Interaction with Drugs

Taking Trupin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Eurolam
SERIOUS
Brand(s): Psycolith
SERIOUS
Brand(s): Psycopan
SERIOUS
Brand(s): Risure
SERIOUS
Brand(s): Panik
SERIOUS
Brand(s): Vlx
SERIOUS
Brand(s): Tremash
SERIOUS
Brand(s): Zosert
SERIOUS
Brand(s): Shinosun
SERIOUS

Patient Concerns

Questions Related to Trupin

arrow
I have hyperacidity pitta gas due to which i have high blood pressure and anxiety disorder some time whwn there is no gas my bp comes normal doctor has given me telpress ct 40 how can the bp come in control and all report are normalMy bp was 160/100
Dr. Aanchal Maheshwari
Ayurveda
Take avipattikar churan 1 spoon twice with water before meal, kaam dudha ras 1 tab twice, brahmi vati 2 tablet twice with water
sir if i mastribute 2 times per day i got nervou and muscle tightness sleepinessand eyes was paining (litle bit) and i have anxiety disorder using tabs from 20 days
Dr. Pranay Gandhi
Sexologist
1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects
arrow
Do you have any questions related to Trupin 25 mg Tablet?

FAQs

Q. Is Trupin a sedative?

No. Trupin is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.

Q. Is Trupin a muscle relaxant?

No. Trupin is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.

Q. What is the difference between Trupin and amitriptyline?

Trupin is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.

Q. Is Trupin the same as doxepin?

Trupin and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.

Q. How to stop Trupin?

If your doctor asks you to stop Trupin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.

Q. Is Trupin fatal?

Yes. Trupin can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.

Q. Can Trupin be used along with mirtazapine?

It is better to avoid Trupin with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Trupin.

Q. Can Trupin be used with citalopram?

No. Citalopram and Trupin both are the antidepressant. Citalopram may increase the high blood level of Trupin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can Trupin be used with sertraline?

No. Sertraline and Trupin both are the anti-depressant. Sertraline may increase the high blood level of Trupin. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.

Q. Can I take Trupin with diazepam?

It is better to avoid this combination. Diazepam is a sedative drug and Trupin may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.

Q. Can Trupin be used in the treatment of trigeminal neuralgia?

No. Trupin is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.

Q. Can Trupin be used in the treatment of burning mouth syndrome?

No. Trupin is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.

Q. Can I take Trupin for depression?

Yes. Trupin is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.

Q. Can Trupin used to treat IBS (Irritable Bowel Syndrome)?

No. Trupin is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.

Q. Can Trupin be used to treat insomnia with depression?

Yes. Trupin may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.

Q. Can I use Trupin for fibromyalgia?

Yes. Trupin is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.

Q. Can I use Trupin for nerve pain?

Yes. Trupin is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
  2. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  3. PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
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