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02 Apr 2020 | 04:38 PM (IST)
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Overview

Introduction

Triple Antigen Vaccine is a combination of three vaccines used to prevent diphtheria, tetanus, and whooping cough. It stimulates the immune system to act against microorganisms to prevent such infections.

Triple Antigen Vaccine is to be administered by a healthcare professional. It may cause redness, pain, and swelling at the site of injection. However, this is temporary and usually resolves on its own. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

Common side effects of this medicine include weakness, injection site redness, pain, swelling, and headache. Please consult your doctor if these do not subside or bother you. Your doctor will suggest ways to cope up with the side effects.

Before taking it, inform your doctor if you are suffering from any liver or kidney problems. Pregnant and breastfeeding mothers should consult their doctor before taking it.

Uses of Triple Antigen Injection

  • Prevention of diphtheria, tetanus and whooping cough

Side effects of Triple Antigen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Triple Antigen

  • Headache
  • Injection site redness
  • Pain
  • Swelling
  • Weakness
  • Gastrointesinal symptoms

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Injection site redness
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Pain
    Some people use herbal remedies, acupuncture and psychological therapies to manage pain. Using hot and cold compress can also help reduce the pain temporarily. Ask your doctor about suitable painkillers if it bothers you or does not go away.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.

How to use Triple Antigen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Triple Antigen Injection works

Triple Antigen Vaccine is a combination of three vaccines. They help develop immunity by initiating a mild infection. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Triple Antigen Vaccine. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Triple Antigen Vaccine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Triple Antigen Vaccine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Triple Antigen Vaccine alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Triple Antigen Vaccine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Triple Antigen Vaccine may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Triple Antigen Vaccine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Triple Antigen Vaccine may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Triple Antigen Vaccine
₹11.31/ml of Injection
Abhay Tag Injection
Indian Immunologicals Ltd
₹17.5/ml of Injection
55% costlier

Patient Concerns

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Can I give flexon to one and a half month baby after first triple vaccine
Dr. Gopal Samdani
Paediatrics
Generally paracetamol is enough. In some situation you can.Consult before that.
Suffering from fever from last 4 days taken sinarest, monocef o 200mg and betenesol. Yesterday I was feeling good bt today again suffering from fever cough cold weakness and body pain.
Dr. Sfurti Mann
Internal Medicine
Get CBC dengue serology MP antigen done
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Do you have any questions related to Triple Antigen Vaccine ?

FAQs

Q. What is Triple Antigen?

Triple Antigen is a combination vaccine that helps protect against three different infectious diseases - diphtheria, tetanus, and pertussis. Triple Antigen is used for booster vaccination against these three diseases in children (aged 4 years and above) and in adults. This vaccine is given to people who have already completed primary vaccination with the DPT vaccine. Diphtheria (a serious throat infection that may block airways), pertussis (respiratory infection known as whooping cough), and tetanus (lockjaw, muscle spasms, and paralysis) are serious and life-threatening diseases, which can be easily prevented with the help of proper vaccination.

Q. What is a booster dose or booster vaccine or booster shot?

A booster dose or booster vaccine or booster shot is an additional dose of a vaccine that may have to be administered periodically (usually once every few years) after completing the initial or primary vaccination against certain diseases. This helps to ‘boost’ your immunity against such diseases so that you are adequately protected against them.

Q. How does Triple Antigen work?

Triple Antigen works by causing the body to produce its own protection (antibodies) against three life-threatening diseases caused by bacterial infection, that is diphtheria, tetanus and pertussis (whooping cough).

Q. When should Triple Antigen not be given?

Triple Antigen should not be given if you have had an allergic reaction to Triple Antigen or any of its ingredients. Signs of an allergic reaction may include itchy skin rash, shortness of breath or swelling of the face or tongue. Get emergency medical help if you notice any such signs. Consult your doctor if you have a severe infection with a high temperature. A minor infection such as a cold should not be a problem, but talk to your doctor about , greater than or equal to 40°C. this before being vaccinated. Triple Antigen should be avoided if the person has experienced any inflammation of the brain or problems with the nervous system within 7 days after previous vaccination with a vaccine against pertussis (whooping cough) disease. If you have experienced a temporary reduction in blood platelets (which increases risk of bleeding or bruising), or problems with the brain or nerves after previous vaccination with a vaccine against diphtheria and/or tetanus, this vaccine cannot be given. Do not use this vaccine if the expiry date printed on the pack has passed or if the packaging is torn or shows signs of tampering. If you are not sure whether Triple Antigen should be given, talk to your doctor.

Q. How is Triple Antigen given?

Triple Antigen is only given by a doctor or a trained healthcare professional into a muscle (intramuscularly), normally the upper arm muscle. Do not administer this vaccine yourself. Firm pressure should be applied to the injection site, without any rubbing, for at least two minutes. Due caution should be exercised, especially in patients with bleeding problems or low platelet counts since they are at risk of bleeding, following an injection into a muscle. In patients with bleeding problems, the dose may need to be given under the skin (subcutaneously). Triple Antigen is never given into a vein (intravenously).

Q. How many doses of Triple Antigen are needed?

A single dose of Triple Antigen is recommended and helps keep you protected from diphtheria, tetanus and pertussis. Repeat vaccination against these diseases should be performed at intervals as per official recommendations (generally every 10 years).

Q. What if I miss a dose of Triple Antigen?

If a scheduled booster dose of Triple Antigen is missed, talk to your doctor and arrange another visit as soon as possible.

Q. What are the side effects of Triple Antigen?

The most common side effects of Triple Antigen are headache, injection site redness, pain or swelling and weakness. It may also cause gastrointestinal symptoms such as loss of appetite or feeling sick (nausea), vomiting, constipation or diarrhea. Not everyone experiences these side effects. If any of these side effects worry you or persist for a longer duration of time, please consult your doctor.

Q. Who should get Triple Antigen?

Triple Antigen may be administered from the age of 4 years onwards, as per the advice of your doctor. It is recommended that adults get one dose of Triple Antigen in place of their next tetanus-diphtheria booster if they have never got this vaccine before. A tetanus-diphtheria booster is usually given once every 10 years to adults. You may need Triple Antigen before the 10-year interval if you are going to be in close contact with a newborn or if you are pregnant. Consult your doctor to find out if you need to get this vaccine.

Q. Can I faint because of Triple Antigen?

Syncope (fainting) can occur following, or even before, any vaccination especially in adolescents as a psychogenic response to the needle injection. This can be accompanied by several neurological signs such as transient visual disturbance, paraesthesia and tonic-clonic limb movements during recovery. It is important that procedures are in place to avoid injury from faints.

Q. Is Triple Antigen safe to use in pregnancy and lactation?

Yes, Triple Antigen is generally safe to be used in pregnancy and lactation. However, inform your doctor if you are planning to conceive, pregnant or breastfeeding before taking Triple Antigen to receive more details on the appropriate time to receive Triple Antigen.

Q. What are the benefits of Triple Antigen during pregnancy?

Triple Antigen during pregnancy provides protection to both the mother and baby by transfer of vaccine-induced antibodies during the pregnancy. There is an additional benefit of reduced risk of transmission of infection from the mother to baby. It actually is a win-win situation. The baby is protected before birth and protection continues even after birth (for the first year of life). Infants are not adequately protected, especially against pertussis at birth. The vaccination for newborn babies, especially against pertussis, begins only at 6 weeks, that might put them at risk of developing the disease and its complications at birth in the first few months of life.

Q. Is Triple Antigen a safe vaccine?

Various studies and trials have shown that Triple Antigen is a safe and effective vaccine. Hence, it has been approved for use and recommended by various medical organizations and doctors all around the world. By preventing life-threatening diseases like diphtheria, pertussis and tetanus, it has proven to be of immense benefit. Triple Antigen is also well tolerated. Any side effects that may be seen with this vaccine are usually minor and tend to resolve quickly.

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Boostrix [Diphtheria, Tetanus and Pertussis (Acellular Component) Vaccine (Adsorbed, reduced antigens content) Ph. Eur.]. Mumbai, India: GlaxoSmithKline Pharmaceuticals Limited; 2019. [Accessed 12 Jul. 2019] (online) Available from:External Link
  2. Boostrix (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed). Rixensart, Belgium: GlaxoSmithKline Biologicals; 2019. [Accessed 11 Jul. 2019] (online) Available from:External Link
  3. Boostrix: Product Information. Abbotsford, Victoria: GlaxoSmithKline Australia Pty Ltd.; 2017. [Accessed 11 Jul. 2019] (online) Available from:External Link
  4. Tripacel [Pertussis Vaccine Combined with Diphtheria and Tetanus Toxoids Adsorbed]. Toronto, Ontario: Sanofi Pasteur Limited; 2013. [Accessed 17 Jul. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India
A licensed vendor partner from your nearest location will deliver Triple Antigen Vaccine. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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