Trental 20mg/1ml Infusion

Prescription Required
Manufacturer
Storage
Store at room temperature (10-30°C)

Introduction

Trental 20mg/1ml Infusion is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.

Trental 20mg/1ml Infusion is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Common side effects of this medicine include nausea, vomiting, diarrhea, headache, flushing (sense of warmth in the face, ears, neck, and trunk), and weakness. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Trental Infusion

Benefits of Trental Infusion

In Peripheral vascular disease

Peripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. Trental 20mg/1ml Infusion prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). It helps prevent the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

In Intermittent claudication

Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Trental 20mg/1ml Infusion helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent formation of blood clots, improves blood flow and maintains free flowing of blood in your body.

Side effects of Trental Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trental

  • Bloating
  • Diarrhea
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Heartburn
  • Lightheadedness
  • Nausea
  • Stomach discomfort
  • Vomiting
  • Weakness
  • Headache

How to use Trental Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Trental Infusion works

Trental 20mg/1ml Infusion is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Trental 20mg/1ml Infusion. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Trental 20mg/1ml Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Trental 20mg/1ml Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Trental 20mg/1ml Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Trental 20mg/1ml Infusion should be used with caution in patients with kidney disease. Dose adjustment of Trental 20mg/1ml Infusion may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Trental 20mg/1ml Infusion in patients with liver disease. Please consult your doctor.

What if you forget to take Trental Infusion?

If you miss a dose of Trental 20mg/1ml Infusion, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Do not drive or perform activities that require mental focus until you know how Trental 20mg/1ml Infusion affects you.
  • Your doctor may get regular blood tests done to monitor liver function while taking this medicine. 
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Methylxanthine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Rheologic modifier

Interaction with Drugs

Taking Trental with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Neil, Sanim
LIFE-THREATENING
Brand(s): Oxy Triactin, Sioril
LIFE-THREATENING
Brand(s): Pyregin, Alpagin, Novalgin RC
LIFE-THREATENING

Patient Concerns

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I have been prescribed Trental 400 mg.How long should l take Trental 400 mg under prescription ?
Dr. Vikas Sharma
Neurology
duration depends on the the reason for giving this medicine
What is medicine for claudication
Dr. Jyoti Kapoor Madan
Psychiatry
Please consult a vascular surgeon
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Do you have any questions related to Trental 20mg/1ml Infusion ?

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
  2. Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
  4. Drugs.com. Pentoxifylline. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of Origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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