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21 Feb 2020 | 12:19 PM (IST)
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Toritz 100mg Injection


Overview

Introduction

Toritz 100mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.

Toritz 100mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.

Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Toritz Injection

Side effects of Toritz Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Toritz

  • Headache
  • Weakness
  • Edema (swelling)
  • Infection
  • Hair loss
  • Itching
  • Chills
  • Febrile neutropenia
  • Decreased white blood cell count (neutrophils)
  • Infusion reaction
  • Increased risk of infection
  • Decreased blood cells (red cells, white cells, and platelets)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Infection, Decreased white blood cell count (neutrophils), and Increased risk of infection
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.
  • Coping with Hair loss
    Use gentle hair products such as baby shampoo. Use a soft brush and comb gently. Avoid using hairdryers, curling tongs or hair straighteners and pat your hair dry after washing. Do not color your hair. Protect your scalp by covering your head in the sun. It is necessary to not take the stress and eat a balanced, nutritious diet as it is vital for the health of your hair.

How to use Toritz Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Toritz Injection works

Toritz 100mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Toritz 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Toritz 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Toritz 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Toritz 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Toritz 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Toritz 100mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Toritz 100mg Injection in patients with liver disease. Please consult your doctor.
Use of Toritz 100mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.

What if you forget to take Toritz Injection?

If you miss a dose of Toritz 100mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Toritz 100mg Injection
₹9466.25/Injection
Maball 100mg Injection
Hetero Drugs Ltd
₹610.81/ml of Injection
save 94%
Mabtas N 100mg Injection
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₹738.94/ml of Injection
save 92%
Mabtas T 100mg Injection
Intas Pharmaceuticals Ltd
₹750/ml of Injection
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Reditux 100 Injection
Dr Reddy's Laboratories Ltd
₹770.83/ml of Injection
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Rituxirel 100mg Injection
Reliance Life Sciences
₹770.83/ml of Injection
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Quick Tips

  • It is given as a drip (intravenous infusion) by your doctor or nurse.
  • You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
  • Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor  if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.

Patient Concerns

arrow
Non Hodgkin lymphoma of defuss large b cells
Dr. Vijay Sharnangat
Medical Oncology and Hematology
I am very much experienced in treating DLBCL
Symptoms of lymphoma And blood cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms could be like fever, weight loss, anorexia, lymphadenopathy.
arrow
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1745-48.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1225-27.
  4. Rituximab. Garden City, Hertfordshire: Roche Products Limited; 1998 [revised 18 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rituximab. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer Address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
A licensed vendor partner from your nearest location will deliver Toritz 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP9466.25  Get 15% OFF
Best Price
₹8046.31
1 Injection in 1 vial
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