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PhD (Pharmacology), PGDPRA
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
14 Jun 2018 | 06:39 PM (IST)
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Tolnex 300 mg/800 mg Tablet


Overview

Uses of Tolnex Tablet

Tolnex Tablet side effects

Common
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Gout
  • Visual impairment

How to use Tolnex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolnex 300 mg/800 mg Tablet is to be taken empty stomach.
Avoid Tolnex 300 mg/800 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Tolnex Tablet works

Tolnex 300 mg/800 mg Tablet is a combination of two medicines: isoniazid and ethambutol which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering. This kills the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.

Tolnex Tablet related warnings

Alcohol
CAUTION
Tolnex 300 mg/800 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Pregnancy
WEIGH RISKS VS BENEFITS
Tolnex 300 mg/800 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Tolnex 300 mg/800 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Tolnex 300 mg/800 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Tolnex 300 mg/800 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tolnex 300 mg/800 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Tolnex 300 mg/800 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tolnex 300 mg/800 mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Tolnex 300 mg/800 mg Tablet
₹5.5/Tablet
₹7.92/Tablet
44% costlier
Myconex 800 Tablet
Cadila Pharmaceuticals Ltd
₹9.16/Tablet
67% costlier
Econex 300mg/800mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹7.67/Tablet
39% costlier
Iso Koxi 300 mg/800 mg Tablet
Shreya Life Sciences Pvt Ltd
₹9.67/Tablet
76% costlier
₹6.72/Tablet
22% costlier

Patient Concerns

Questions Related to Tolnex

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Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetes Specialist
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
Sir,I'm a tb patient ,doctor give me medicine,but i don't know how i take this medicine ,before meal or after meal please help meThis is my medicineSolonex 300 mg R cin 600mg Pyzina 1500mg combutol 1000mg Pyridoxin 40mg
Dr. Pushkar Mani
Diabetes Specialist
That u have to ask ur and also u visit dots centre for tuberculosis tratment
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Do you have any questions related to Tolnex 300 mg/800 mg Tablet?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 09 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
4, Lady Desika Road, Chennai – 600004., Tamil Nadu, India.
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