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TOBRACEF 1000MG/120MG INJECTION

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MRP: Rs. 450 for 1 vial(s) (10 ML injection each)
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Composition for TOBRACEF

Ceftazidime(1000 mg),Tobramycin(120 mg)

food interaction for TOBRACEF

alcohol interaction for TOBRACEF

pregnancy interaction for TOBRACEF

lactation interaction for TOBRACEF

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Tobracef 1000mg/120mg injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for TOBRACEF

Ceftazidime(1000 mg)

Uses

Ceftazidime is used in the treatment of bacterial infections and typhoid fever.

How it works

Ceftazidime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Liver enzyme increased, Diarrhoea, Dizziness, Fever, Injection site pain, Injection site redness, Black and bloody stools, Reduced blood platelets, Stomach cramp, Vomiting
Tobramycin(120 mg)

Uses

Tobramycin is used in the treatment of bacterial infections.

How it works

Tobramycin is an antibiotic. It kills bacteria by inhibiting synthesis of essential proteins, required by bacteria to carry out vital functions.

Common side effects

Nausea, Noisy breathing, Oral fungal infection, Rash, Thoracic pain, Chest pain, Chest tightness, Shortness of breath, Cough, Dizziness, Dry eye, Gastric pain, Fungal infection, Headache, Hearing loss, Coughing up blood, Liver toxicity, Hoarseness of voice, Increased saliva production, Loss of appetite, Mouth ulcer, Tongue ulcer, Ringing in ear, Sore throat, Weakness, Increased sputum production

SUBSTITUTES for TOBRACEF

No substitutes found

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Expert advice for TOBRACEF

  • Ceftazidime is usually given by a doctor or a nurse as an injection directly into the vein or muscle.
  • Do not drive if you feel sleepy or dizzy while being treated with ceftazidime.
  • If you are taking birth conrol pills, ceftazidime can make them less effective. Ask your doctor about using a non-hormone method of birth control while taking this drug to avoid pregnancy.
  • Do not start or continue the ceftazidime and consult your doctor if you are pregnant or planning to become pregnant or breastfeeding.

Frequently asked questions for TOBRACEF

Ceftazidime

Q.Is ceftazidime a sulfa, penicillin or a beta lactam drug?
Ceftazidime does not contain sulfa and is not a penicillin drug. It is beta lactam cephalosporin antibiotic

Q.Is ceftazidime the same as Rocephin?
No, Rocephin is the brand name for ceftriaxone

Q.Is ceftazidime dialyzable?
Yes, ceftazidime is a dialyzable drug

Q.Is ceftazidime and ciprofloxacin compatible?
Yes, ceftazidime and ciprofloxacin are compatible when taken together

Q.What organisms does ceftazidime cover?
Ceftazidime is active against pseudomonas, anaerobes, and staphylococcus bacteria. It may not be effective against methicillin- resistant Staphylococcus aureus (MRSA).

Q.Is ceftazidime nephrotoxic?
No, ceftazidime is not a nephrotoxic drug when given alone but when given along with aminoglycoside antibiotics (gentamicin, tobramycin) or diuretics such as furosemide, it may increase nephrotoxicity.

Tobramycin

Q.Is tobramycin a sulfa drug or penicillin antibiotic?
No. Tobramycin is an aminoglycoside antibiotic used to treat Pseudomonas infections and other serious infections in patients (6 years and older) with cystic fibrosis

Q.Does tobramycin treat styes, Pseudomonas, pink eye, staphylococcus and methicillin resistant staphylococcus aureus (MRSA)?
Tobramycin/dexamethasone combination can be used to cure pink eye and styes, which are superficial eye and eyelid infections. Tobramycin treats Pseudomonas infections however it is not drug of choice in the treatment of staphylococcus or MRSA

Q.Is tobramycin safe for infants?
No. Due to high propensity for kidney and internal ear damage, tobramycin shouldn't be given to infants

Q.Is tobramycin over the counter?
No. Tobramycin belongs to schedule H and can be obtained only on production of valid prescription

Q.Is tobramycin the same as ofloxacin?
No. Tobramycin and Ofloxacin belong to different class of antibiotics, and are used to treat different sets of infections.

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Content on this page was last updated on 18 August, 2015, by Dr. Varun Gupta (MD Pharmacology)