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Composition for TIZARAN

Diclofenac(50 mg),Tizanidine(2 mg)

food interaction for TIZARAN

alcohol interaction for TIZARAN

pregnancy interaction for TIZARAN

lactation interaction for TIZARAN

There is no data available. Please consult doctor before consuming the drug.
Tizaran 50mg/2mg tablet may cause excessive drowsiness and calmness with alcohol.
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Tizaran 50mg/2mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Tizaran 50mg/2mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Diclofenac(50 mg)


Diclofenac is used in the treatment of painful conditions of joints, lower back pain, sprains or bone fractures, inflammation of joints (frozen shoulder, gout), pain and swelling following skeletal muscle, dental and other minor surgeries. It is also used in treatment of migraine.

How it works

Diclofenac belongs to group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation.

Common side effects

Epigastric pain, Renal dysfunction, Stomach ulcer, Bleeding, Toxic epidermal necrolysis, Itching
Tizanidine(2 mg)


Tizanidine is used to treat rigidity of muscles (spasticity) associated with various brain and nerve disorders (like cerebral palsy, meningitis, multiple sclerosis, motor neuron disease, cerebrovascular accidents), diseases of the spinal cord, other injuries which affect the brain and other parts of nervous system in adults.

How it works

Tizanidine belongs to group of medicines called centrally acting muscle relaxants. It acts by blocking the nerve impulses which excites the muscles reducing their tone. As a result, the muscle relaxes and there is reduction of pain and spasms.

Common side effects

Vomiting, Nausea, Abdominal pain, Skin rash, Allergic reaction, Altered vision, Back pain, Bruise, Bleeding, Dizziness, Depression, Drowsiness, Nervousness, Dry mouth, Fatigue, Heartburn, Altered heart rate, Bradycardia, Increased sweating, Influenza like symptoms, Loss of appetite, Muscle cramp, Tingling sensation, Auditory hallucination, Visual hallucination, Weakness, Yellow discoloration of skin, Yellow discoloration of eye, Constipation, Diarrhoea


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Expert advice for TIZARAN

  • Diclofenac should be taken with food or immediately after meals.
  • Take the medicine with food to avoid stomach upset.
  • Do not take antacids withh magnesium as they can interact with the drug.
  • Do not take diclofenac, If  you are allergic to diclofenac.
  • Do not drink alcohol while takig this drug.
  • Do not drive or use any tools or machines, if you feel dizzy, tired, have a headache or get blurred vision after taking diclofenac.

Frequently asked questions for TIZARAN


Q. Is diclofenac safe?
Diclofenac (also available as voveran, dynapar) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is diclofenac nephrotoxic?
Diclofenac can interfere with normal kidney function when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding its uses.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac in asthma.
Q. Is diclofenac banned in India?
Diclofenac is available over-the-counter and it is not banned in India.
Q. Is diclofenac a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, consult your doctor before taking diclofenac if you are already suffering from high blood pressure or any other heart disease.
Q. Does diclofenac induce sleep?
Diclofenac does not induce sleep.


Q. Does tizanidine contain sulfa or asprin?
Tizanidine does not contain sulfa and aspirin.
Q. Is tizanidine an opiate, NSAID, blood thinner, controlled substance, or muscle relaxer?
Tizanidine is not an opiate, NSAID, blood thinner or a controlled substance. It is a muscle relaxant.
Q. Is tizanidine like valium?
Valium is a brand name for drug diazepam. It is also used as a muscle relaxant, but both have different functions. Please consult your doctor before taking the drug.
Q. Is tizanidine stronger than Flexeril?
Flexeril is a brand name for drug cyclobenzaprine, which is also used as a muscle relaxant. Effect of the drug may vary upon individual response. Please consult your doctor before taking the drug.
Q. Is tizanidine water soluble?
Tizanidine is a lipid-soluble drug; it is only slightly soluble in water and methanol.
Q. Is tizanidine gluten free?
Tizanidine is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Can I take tizanidine or Zanaflex for menstrual cramps, headaches, or anxiety?
No, you cannot take tizanidine or Zanaflex (which contains tizanidine) for menstrual cramps, headaches, or anxiety. Please consult your doctor before taking the drug.
Q. Does tizanidine cause weight loss or keep you awake (insomnia)?
You may experience insomnia or weight loss with the use of tizanidine. Few people may experience excessive sleepiness. If you experience such side effects, consult your doctor.
Q. Can I take tizanidine with Aleve (naproxen), Ambien (zolpidem), Norco (acetaminophen and hydrocodone), Tylenol (paracetamol), Valium (diazepam), or Xanax (alprazolam)?
You may take Aleve and Tylenol with tizanidine, but Ambien, Norco, Valium, and Xanax should not be given with tizanidine. Consult your doctor before simultaneous use.
Q. Can I take tizanidine with prednisone, ibuprofen, tramadol, or oxycodone?
Tizanidine may be taken with prednisone or ibuprofen, but tramadol or oxycodone with tizanidine may increase their side effects. Consult your doctor before simultaneous use.
Q. Does tizanidine show on a drug test?
No, tizanidine does not show on a drug test. Only narcotic drugs show up on a drug test.


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)