Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thyronorm 175 mcg Tablet is to be taken empty stomach.

Thyronorm 175 mcg Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).

In Depth Information on Thyronorm Tablet

Expert advice for Thyronorm Tablet

Your doctor has prescribed Thyronorm 175 mcg Tablet to replace the natural thyroid hormone that your own thyroid gland can no longer make.
It is best to take it on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Thyronorm 175 mcg Tablet is a lifelong medication. Do not discontinue it without first discussing with your doctor.
Inform your doctor if you have diarrhoea, nervousness, irritability, feeling of a heartbeat, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Thyronorm 175 mcg Tablet as all brands may not have the same effect.

Thyronorm Tablet related warnings

Special precautions for Thyronorm Tablet

Alcohol

Interaction with alcohol is unknown. Please consult your doctor.

Pregnancy

SAFE

Thyronorm 175 mcg Tablet is safe to use during pregnancy.
Adequate and well-controlled human studies have shown low or no risk.

Lactation

SAFE

Thyronorm 175 mcg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

Driving

SAFE

Thyronorm 175 mcg Tablet does not usually affect your ability to drive.

Kidney

There is limited information available on the use of Thyronorm 175 mcg Tablet in patients with kidney disease. Please consult your doctor.

Liver

There is limited information available on the use of Thyronorm 175 mcg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Thyronorm Tablet?

If you miss a dose of Thyronorm 175 mcg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Thyronorm Tablet

Frequently asked questions about Thyroxine / Levothyroxine

Q. Can I take Thyronorm during pregnancy?

Thyroid hormone is naturally present in the body and is therefore safe to take in pregnancy. In fact, it is very important that pregnant women or those planning to become pregnant have normal thyroid hormone levels to provide a suitable environment for the baby. If you are already taking thyroid hormone, your dose may need to be increased during pregnancy. Hence, you may have to get your thyroid hormone and TSH levels measured once you know that you are pregnant. You should discuss the timing of thyroid blood tests with your doctor, but often thyroid tests are done every trimester.

Q. Does Thyronorm interact with any other medications?

Use of medications such as birth control pills, estrogen, testosterone, some medications for seizures, depression, and cholesterol, and supplements such as iron and calcium may require you to alter the dose of Thyronorm. It is therefore important that you let your doctor know about all the medications or supplements you are taking.

Q. What is the dose for Thyronorm?

The dose is individualised on the basis of clinical response and biochemical tests. Regular monitoring of thyroid stimulating hormone (TSH) and Thyronorm is recommended when starting therapy or changing the dose. Do not change the dose or stop the medicine without consulting your doctor.

Q. Can I take Thyronorm with tea/coffee/food?

It is best to take Thyronorm on an empty stomach (ideally, first thing in the morning). No tea/coffee, food or milk should be taken 1 hour before and 2 hours after taking this medicine as it affects its absorption.

Q. What happens if we consume too much iodine?

In some people, increased dietary iodine intake causes the thyroid gland to make excess of thyroid hormone, leading to a condition called iodine-induced hyperthyroidism. Too much of iodine can also cause thyroid underactivity, called hypothyroidism as excess iodine blocks the thyroid's ability to produce the hormone.

Q. Is Thyronorm a beta blocker?

No. Thyronorm is not a beta-blocker. It is a hormone synthesised by the thyroid gland present in the neck region. It maintains normal growth & development, body temperature & energy levels.

Q. Is Thyronorm a blood thinner?

No. Thyronorm is not a blood thinner. It is a hormone used for the treatment of hypothyroidism (decreased thyroid hormone). Blood thinners are medicines which prevent abnormal clot formation.

Q. Does Thyronorm cause weight loss?

Yes. Thyronorm can produce side effect as weight loss. It is usually due to excessive dose. However, it should not be used for treat obesity.

Q. Is Thyronorm a growth hormone?

No, Thyronorm is not a growth hormone. It is a hormone synthesized by the thyroid gland present in the neck region. Growth Hormone, on the other hand, is secreted by the pituitary gland present in the brain. Thyronorm is required for the proper functioning of growth hormone.

Q. Is Thyronorm a neurotransmitter?

No, Thyronorm is not a neurotransmitter. Thyronorm is a hormone secreted directly into the blood by the thyroid gland. The blood then takes it to the target organs in the body. A neurotransmitter, on the other hand, transmits impulses from one nerve cell to the other in the brain.

Q. Is Thyronorm a tropic hormone?

Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the pituitary gland in the brain. The thyroid gland secretes Thyronorm, which targets the hypothalamus and therefore can be considered a tropic hormone.

Q. Is Thyronorm a protein?

No. Thyronorm is not a protein. The normal thyroid gland secretes two thyroid hormones - triiodothyronine (T3) and tetraiodothyronine (T4 or Thyronorm). More than 99% of these hormone circulating in the blood as bound to carrier proteins, Thyronorm-binding globulin, synthesised in the liver.

Q. Is Thyronorm a peptide or steroid?

Thyronorm is neither a peptide nor a steroid. Thyronorm is an amino acid (tyrosine) derived hormone. (Amino acids are tiny building blocks of proteins, but they cannot be called proteins by themselves unless a number of them are connected in a sequence).

Q. Can Thyronorm be used as hormone replacement therapy?

Yes. Thyronorm can be used as a hormone replacement therapy to compensate the deficiency of thyroid hormone in the body.

Q. Is Thyronorm a hormone?

Yes. Thyronorm is a hormone secreted from the thyroid gland. It causes increased oxygen consumption by most tissues of the body, increases the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins.

Q. Is Thyronorm a slowly acting drug?

Yes. Thyronorm is a slow-acting drug. It acts through receptors situated in the nucleus of a cell and results in the formation of various protein to target its action hence Thyronorm takes some time to act.

Q. Is Thyronorm a diuretic?

No. Thyronorm is not a diuretic. It is a hormone secreted by the thyroid gland.

Q. What is Thyronorm poisoning?

Thyronorm poisoning occur if an excessive dose is taken. It present as a headache, hyperactivity, nervousness, anxiety, irritability, heat intolerance, fever, excessive sweating, palpitations, tachycardia, arrhythmias, increased pulse and blood pressure. Inform your doctor as soon as possible.

Q. How Thyronorm modulates erythropoiesis?

Thyronorm is required for the normal functioning of the body. Research has shown that thyroid hormone significantly affects the erythropoiesis and increases red blood cell synthesis. Thyronorm is not approved to treat anemia (decreased red cell count).

Q. In which condition does Thyronorm is used along with carbimazole?

Thyronorm is used with carbimazole in the treatment of Graves disease or hyperthyroidism. Studies have shown it is used as block–replace regimen which means the option of maintaining the high dose of antithyroid drugs along with adding levothyroxine to maintain normal thyroid state.

Q. Can I take an antidepressant along with Thyronorm?

No. There are noted interactions between Thyronorm and few antidepressants which lead to increased adverse effects of both the drugs so consult your doctor and do inform him before prescribing any of the medication.

Q. What is the effect of grapefruit juice on the absorption of Thyronorm?

Grapefruit juice slightly decreases the absorption of levothyroxine when taken together otherwise there is no major interaction between these two.

Q. Can I take vitamins with Thyronorm and what would be its effects?

Yes. Vitamins can be added to your diet and can be taken with Thyronorm, but you should not take vitamin supplement within four hours of taking your thyroid medication.

Q. Can I take omeprazole along with Thyronorm?

No. Omeprazole should not be taken with Thyronorm. Omeprazole increases the gastric pH and interferes with the absorption of the Thyronorm.

Q. Can I take Thyronorm with iron tablets?

No. Thyronorm should not be taken with the iron tablet. The absorption of Thyronorm is decreased when taken together. You should take them with a gap of 4 hours between them.

Q. Can I take Thyronorm with calcium?

No. Thyronorm should not be taken with calcium. The absorption of Thyronorm is decreased when taken with calcium. You should take them with a gap of 4 hours between them.

Q. Can Thyronorm be used in the treatment obesity?

No. Thyronorm should not be used to treat obesity. It can cause weight loss as a side effect but it should not be used for the treatment of obesity as it can cause serious life-threatening side effects if given with other weight reducing medications.

Q. Can Thyronorm be used in the treatment of depression?

No. Thyronorm is not approved for use in depression. But some of the research studies have shown that adding Thyronorm to the antidepressant medication therapy has increased the effectiveness of antidepressant therapy in the patients.

Q. Can Thyronorm help you get pregnant?

Thyronorm treats hypothyroidism (decreased thyroid hormone) and associated complications leading to increases chances of conceiving. Consult your doctor before starting Thyronorm as failure to conceive is not merely due to decreased thyroid hormone but due to several other factors. Always start the medicine consulting with the doctor.

Q. Should I take Thyronorm in morning or evening?

It is preferred to take Thyronorm in morning on empty stomach. Research has shown that even if it is given in the evening, it shows the same effects as compared to morning. It is not practised because of ensuring an empty stomach by the patient.

Q. Is it safe to take Thyronorm if I have a cardiac disease?

Yes. Thyronorm can be used but at a lower dose or given on an alternate day. There are high chances of side effects in a person with the cardiac disease like an increase in heart rate, cardiac wall thickness, and cardiac contractility and it may precipitate angina or irregular heart rhythms. Inform your doctor if you have heart disease. You may adjust the dose.

Q. What are the serious side effects of Thyronorm?

The serious side effects of Thyronorm are usually due to excessive doses, so symptoms are similar to hyperthyroidism. It may cause diarrhoea, vomiting, weight loss with increased appetite, palpitations, angina, insomnia and restlessness. Inform your doctor if you have these symptoms.

Q. Can I take antacids with Thyronorm?

No. Thyronorm should not be taken with an antacid. The absorption of Thyronorm is decreased when taken together. You should take them with a gap of 4 hours between them.

Q. When should I get thyroid function test after starting Thyronorm?

Thyroid function test should be measured three months after starting treatment or change in dose.

Q. Can Thyronorm be taken along with MAO inhibitor?

Yes. Thyronorm can be taken with MAO inhibitors. Consult your doctor before starting these medications.

Information last updated by Dr. Varun Gupta, MD Pharmacology on 10th Jul 2018.

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