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Composition for THIAZIDE

Hydrochlorothiazide(12.5 mg)

food interaction for THIAZIDE

alcohol interaction for THIAZIDE

pregnancy interaction for THIAZIDE

lactation interaction for THIAZIDE

It is better to take Thiazide 12.5 mg tablet with food.
Taking Hydrochlorothiazide with alcohol may have additive effects in lowering blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Thiazide 12.5 mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Hydrochlorothiazide(12.5 mg)


Thiazide 12.5 mg tablet is used to treat high blood pressure (hypertension). It also treats fluid retention (edema) due to congestive heart failure or cirrhosis of liver or kidney disorder.

How it works

Thiazide 12.5 mg tablet belongs to class of medications called thiazide diuretics. It acts by eliminating the fluid and salts from the body. It works on the kidneys to produce more urine which removes extra water and certain salts from the body which in turn lowers blood pressure and swelling.

Common side effects

Increased sensitivity to light, Excessive thirst, Abnormal heart rhythm, Skin rash, Allergic reaction, Altered blood lipids, Convulsion, Drowsiness, Dry mouth, Electrolyte imbalance, Vomiting, Gastrointestinal disorder, Gout, Headache, Increased glucose level in blood, Increased uric acid level in blood, Decreased potassium level in blood, Decreased magnesium level in blood, Decreased sodium level in blood, Decreased blood pressure, Lethargy, Muscle pain, Weakness


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Expert advice for THIAZIDE

Do not chew, divide or crush the tablets, swallow it whole with water. Avoid taking hydrochlorothiazide at bedtime because it makes you urinate more often. It is recommended to take in early morning. Drink adequate amount of liquid to avoid becoming dehydrated or overheated. Consult your doctor if you experience any of these side effects: dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, confusion, muscle pains or cramps that doesn't go away. Do not start or continue the tablet:
  • If you are allergic to sulfonamide-derived drugs (Sulfa drugs).
  • If you have diabetes or increase lipid levels (cholesterol).
  • If you are pregnant or planning to become pregnant.
  • If you have any other disease such as kidney disease, liver disease, heart disease, diabetes or gout, asthma and lupus erythematosus (an allergic condition which causes joint pain, skin rashes and fever).
Get up slowly from lying position to avoid dizziness. This is more common when hydrochlorothiazide is taken for the first time.Use sunscreen for photosensitivity. Avoid drinking alcohol, OTC medicines unless recommended by doctor.

Frequently asked questions for THIAZIDE


Q. Hydrochlorothiazide is a diuretic,which increases the excretion of urine?
Patients should follow the advice of the doctor regarding its use.
Q. Is hydrochlorothiazide a statin/ opiate?
No.It is the derivative of chlorothiazide.
Q. Is hydrochlorothiazide bad for your kidneys?
No.Hydrochlorthiazide is a safe drug at prescribed dose by your doctor. Consult your doctor if you have kidney disease and follow the advice of the doctor regarding its use.
Q. Can I take hydrochlorothiazide with lisinopril/ ibuprofen/ synthroid/ aspirin/ potassium/ phentermine/ losartan/ naproxen/ magnesium/ vitamins?
Taking other medicines may alter the effects of hydrochlorothiazide. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does hydrochlorothiazide cause diabetes/ erectile dysfunction/ weight loss/ gout/ constipation/tinnitus/ potassium loss?
Hydrochlorothiazide causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.
Q. Does hydrochlorothiazide have sulfa in it?
Yes.Hydrochlorothiazide has sulfa and it is chemically known as 6-chloro- 3, 4-dihydro-2 H-1, 2, 4-benzothiadiazine-7-sulfonamide 1, 1-dioxide.
Q. Does hydrochlorothiazide clean your system?
No.Hydrochlorothiazide reduces extra fluid in the body.


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)