Medicine Overview of Tenepure-M Tablet ER
Side Effects of Tenepure-M are Diarrhoea, Nausea, Vomiting, Stomach upset, Headache, Nasal congestion, Sore throat, Respiratory tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenepure-M 1000 Tablet is to be taken with food.
Tenepure-M 1000 Tablet may cause stomach upset if taken on empty stomach.
Tenepure-M 1000 Tablet is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.
In Depth Information on Tenepure-M Tablet ER
- You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
- Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Take it with food to lower your chance of having an upset stomach.
- Monitor your blood sugar level regularly while you are taking this medicine.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain as Tenepure-M 1000 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Tenepure-M Tablet ER related warnings
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Unknown. Human and animal studies are not available. Please consult your doctor.
No information is available on the use of Tenepure-M 1000 Tablet during lactation. Please consult your doctor.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Tenepure-M 1000 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tenepure-M 1000 Tablet may be needed. Please consult your doctor.
Use of Tenepure-M 1000 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Tenepure-M 1000 Tablet should be used with caution in patients with liver disease. Dose adjustment of Tenepure-M 1000 Tablet may be needed. Please consult your doctor.
Tenepure-M 1000 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
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Frequently asked questions about Tenepure-M Tablet ER
Tenepure-m is a combination of two medicines: Metformin+Teneligliptin. This medicine is used in the treatment of type 2 diabetes mellitus (DM) along with diet and exercise to improve blood glucose levels in adults. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Teneligliptin nhibits the enzyme DP4 inhibitor and increases release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.
Q. What are the possible side effects of Tenepure-m?
The use of Tenepure-m is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious, but rare side effect lactic acidosis. On long term use it can also lead to Vitamin B12 deficiency.
Q. Are there any specific conditions in which Tenepure-m should not to be taken?
The use of Tenepure-m should be avoided in patients with known allergy to any of the component or excipients of this medicine. The use of this medicine is also contraindicated in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis, with or without coma.
Q. Is it safe to take alcohol while I am also taking Tenepure-m?
No, it is not safe to take Tenepure-m along with alcohol, as it can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or hepatic impairment.
Q. Can the use of Tenepure-m cause hypoglycemia?
The use of Tenepure-m does not usually cause hypoglycemia (low blood sugar level) alone, but could occur when supplementation of calories are insufficient. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, do more than routine exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important and always keep glucose tablets, honey or fruit juice with you.
Q. Can the use of Tenepure-m cause lactic acidosis?
Yes, the use of Tenepure-m can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is contraindicated in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Tenepure-m and immediately consult your doctor.
Q. Can the use of Tenepure-m lead to Vitamin B12 deficiency?
Yes, the use of Tenepure-m can cause vitamin B12 deficiency on long-term use as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in making balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside at least once every year.
Q. Does Tenepure-m expire?
Yes, Tenepure-m does expire. Please check the expiry date written on the pack of this medicine. Do not use Tenepure-m after the expiry date.
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