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Last updated:
23 Mar 2020 | 04:56 PM (IST)
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TEMOZAM 100 MG CAPSULE


Overview

Introduction

TEMOZAM 100 MG CAPSULE is used in the treatment of a specific type of cancer of the brain. It is used to treat brain tumors if they return or get worse after standard treatment. It may be also used to treat other conditions, as determined by the doctor.

TEMOZAM 100 MG CAPSULE should be taken empty stomach and at same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, constipation, headache and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking it, tell your doctor if have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.

Uses of Temozam Capsule

Side effects of Temozam Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Temozam

  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Fatigue
  • Convulsion
  • Coordination disorder
  • Diarrhea
  • Dizziness
  • Fever
  • Hair loss
  • Hemiparesis (weakness on one side of the body)
  • Insomnia (difficulty in sleeping)
  • Loss of appetite
  • Memory loss
  • Rash
  • Viral infection
  • Weakness

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Coordination disorder
    If you feel unsteady, stop what you are doing and sit or lie down until you feel better. Try getting up very slowly from a sitting or lying position. If your condition does not improve, talk with your doctor about changing the dose or trying an alternative medicine.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Hair loss
    Use gentle hair products such as baby shampoo. Use a soft brush and comb gently. Avoid using hairdryers, curling tongs or hair straighteners and pat your hair dry after washing. Do not color your hair. Protect your scalp by covering your head in the sun. It is necessary to not take the stress and eat a balanced, nutritious diet as it is vital for the health of your hair.
  • Coping with Loss of appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Memory loss
    There is a lot you can do to improve your memory. Keep active and take regular exercise to improve blood flow to your whole body, including your brain. Eat a healthy diet so your brain gets the nutrients it needs. Some foods containing omega-3 fatty acids (such as oily fish) may benefit brain health. Keep mentally active. It is important to socialize, so stay in contact with friends and family. Stay organised – keep a diary for things you have to do, keep things you need regularly (such as keys, purse and spectacles) in a set place and do not try to do too many things at once. Make sure you get good sleep, make it a priority. Drinking alcohol can lead to confusion and memory loss, so try to cut down or stop. Also, stop smoking because it reduces the amount of oxygen that gets to your brain. If you are worried about memory loss, talk to your doctor, especially if it affects your ability to live your daily life.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.

How to use Temozam Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. TEMOZAM 100 MG CAPSULE is to be taken empty stomach.

How Temozam Capsule works

TEMOZAM 100 MG CAPSULE is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with TEMOZAM 100 MG CAPSULE. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
TEMOZAM 100 MG CAPSULE is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
TEMOZAM 100 MG CAPSULE is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
TEMOZAM 100 MG CAPSULE may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
TEMOZAM 100 MG CAPSULE is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of TEMOZAM 100 MG CAPSULE may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking TEMOZAM 100 MG CAPSULE.
Liver
CAUTION
TEMOZAM 100 MG CAPSULE should be used with caution in patients with severe liver disease. Dose adjustment of TEMOZAM 100 MG CAPSULE may be needed. Please consult your doctor.
Limited information is available on the use of TEMOZAM 100 MG CAPSULE in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Temozam Capsule?

If you miss a dose of TEMOZAM 100 MG CAPSULE, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
TEMOZAM 100 MG CAPSULE
₹1780.2/Capsule
₹540.03/Capsule
save 70%
₹1521.8/Capsule
save 15%
Temolon 100mg Capsule
Celon Laboratories Ltd
₹1752.38/Capsule
save 2%
Glioz 100mg Capsule
Dr Reddy's Laboratories Ltd
₹1948.87/Capsule
9% costlier
Temodal 100mg Capsule
Fulford India Ltd
₹2029.94/Capsule
14% costlier

Quick Tips

  • TEMOZAM 100 MG CAPSULE should be taken on an empty stomach.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
  • Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.

Patient Concerns

arrow
Is Thalix 100 mg capsule increases blood sugar of patient.
Dr. Alok Gupta
Medical Oncology
No. Increased blood sugar not a common side effect of thalix.
any treatment of brain tumor w
Dr. Saurav Arora
Homeopathy
Dear sir in this case homeopathy can be given as add-on with conventional medicine. By doing so we can improve the longevity of patient, quality of life and decrease disease progression.
arrow
Do you have any questions related to TEMOZAM 100 MG CAPSULE ?

FAQs

Q. What is Temozam used for/ what does Temozam treat/ Is Temozam chemotherapy/ is Temozam cytotoxic/ is Temozam a radiosensitizer?

Temozam is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer

Q. Is Temozam effective/ does Temozam work?

Temozam is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor

Q. How is Temozam given/administered/ metabolized/ how long does Temozam stay in the body?

Temozam is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours

Q. How does Temozam cross the blood-brain barrier?

Temozam because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid

Q. Does Temozam cause hair loss?

Hair loss is a side effect of using Temozam. Always follow doctor's advice regarding its use

Q. Is Temozam FDA approved?

Temozam is a FDA approved drug.

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
  3. Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer Address

Fresenius Kabi AG​ , Else-Kröner-Straße 1 ​ , 61352 Bad Homburg , Germany
A licensed vendor partner from your nearest location will deliver TEMOZAM 100 MG CAPSULE. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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