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Composition for TALENTIL PLUS

Chlorpromazine(100 mg),Trihexyphenidyl(2 mg)

food interaction for TALENTIL PLUS

alcohol interaction for TALENTIL PLUS

pregnancy interaction for TALENTIL PLUS

lactation interaction for TALENTIL PLUS

There is no data available. Please consult doctor before consuming the drug.
Talentil plus 100mg/2mg tablet may cause excessive drowsiness and calmness with alcohol.
Talentil plus 100mg/2mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Chlorpromazine(100 mg)


Chlorpromazine is used for the treatment of schizophrenia (a long-term mental disorder often characterized by abnormal social behaviour and failure to recognize what is real), and other psychosis (in which some or all symptoms of schizophrenia may be present), particularly paranoia (misbeliefs and feelings of harassment), mania [overactive behaviour and hypomania (elated moods and excitability)], anxiety, agitation and violent or dangerously impulsive behaviour. 
Chlorpromazine is also used for prolonged periods of hiccups, nausea and vomiting (when other drugs have failed), to lower body temperature in childhood schizophrenia and autism (learning and communication difficulties).

How it works

Chlorpromazine belongs to a group of medications called phenothiazine antipsychotics. It increases the availability of a chemical called dopamine in the brain thereby relieving the symptoms of schizophrenia and psychosis and also brings about the feeling of well-being in an individual. It inhibits the vomiting centre in the brain, and also decreases saliva and stomach secretions, thereby relieving nausea and vomiting.

Common side effects

Nervousness, Agitation, Absence of menstrual periods, Breast enlargement, Decreased sexual function, Drowsiness, Unusual production of breast milk in women and men, Weight gain, Increased appetite, Insomnia, Lack of facial expression, Restlessness, Tremor
Trihexyphenidyl(2 mg)


Trihexyphenidyl is used to treat symptoms of Parkinson’s disease (a type of nerve disease that causes movement disorder characterized by slowness of movements, muscle stiffness, uncontrolled shaking and poor balance and co-ordination) and drug-induced extra pyramidal symptoms (movement disorders similar to symptoms of Parkinson’s disease) except tardive dyskinesia (involuntary movement of face and jaw). It is often given along with levodopa (anti-Parkinson drug).

How it works

Trihexyphenidyl is an anticholinergic agent, which works by blocking the action of a chemical called acetylcholine on the nerves which results in relaxing of smooth muscles; thereby, reducing the rigidity of muscle spasm (sudden involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson’s disease.

Common side effects

Blurred vision, Confusion, Constipation, Dizziness, Drowsiness, Dry mouth, Difficulty in urination, Eye pain, Skin rash, Fever, Stomach upset, Tachycardia, Heart rate irregular, Vomiting, Diarrhoea


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Expert advice for TALENTIL PLUS

  • Do not use chlorpromazine in children < 1 year unless the need is lifesaving or in children ≤12 years for the treatment of hiccups.
  • Tell your doctor before taking chlorpromazine if you are suffering from liver or kidney disease, epilepsy, Parkinson’s disease, reduced activity of thyroid gland (hypothyroidism), heart disease, raised eyeball pressure (glaucoma), diabetes, tendency to form blood clots or a family history of clotting disorder, pheochromocytoma (high blood pressure due to a tumour near the kidney), or enlarged prostate.
  • Inform your doctor if you have known cardiovascular disease or family history of QT prolongation and if you are taking medicines that may prolong the QT interval.
  • Inform your doctor of other medications that you may be taking for psychiatric disorders, lowering of blood pressure, insomnia, fits, Parkinson’s disease, migraine etc.
  • Do not stop taking chlorpromazine or change its dose without consulting your doctor.
  • Monitor blood glucose regularly while on chlorpromazine treatment, if you are a patient with diabetes
  • Do not drive or operate heavy machinery after taking chlorpromazine as it may cause drowsiness and visual disturbances. 
  • Do not consume this drug if you are allergic to any phenothiazine drug, chlorpromazine or any of its ingredients.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for TALENTIL PLUS


Q. Is chlorpromazine a benzodiazepine/sleeping tablet?
Chlorpromazine is not a benzodiazepine. It belongs to a class of medicines called phenothiazine antipsychotics. Chlorpromazine should not be used as a sleeping tablet.

Q. Is it good for anxiety?
 It is used in patients with schizophrenia but it relieves anxiety too at certain levels.
Q. Is chlorpromazine a controlled substance/narcotic?
No. Chlorpromazine is not a controlled substance/ narcotic. However, it can be purchased only after producing a doctor’s prescription.
Q. Does chlorpromazine cause weight gain/sleepiness/euphoric (high)?
Yes, chlorpromazine may cause weight gain and sleepiness.

Q. Is it addictive?
 Chlorpromazine does not have high addictive potential and a very little propensity for abuse for euphoria.
Q. Does chlorpromazine decrease dopamine?
Chlorpromazine is dopamine receptor blocker so it decreases dopamine levels to calm the patients with schizophrenia.
Q. Does chlorpromazine help with opiate withdrawal?
It has been observed that chlorpromazine helps in certain cases of opiate withdrawal. However, it is not widely used for this purpose. Please follow your doctor’s advice regarding its use.


 Q. Does trihexyphenidyl get you high/ cause weight gain?
Trihexyphenidyl doesn’t make you feel high. It does not cause weight gain
Q. Does trihexyphenidyl work?
Trihexyphenidyl works by blocking the action of a chemical called acetylcholine on the nerves which results in relaxing of smooth muscles; thereby, reducing the rigidity of muscle spasm (sudden involuntary contraction of a muscle or group of muscles), tremor (uncontrolled shaking) and excessive salivation associated with Parkinson’s disease.


Content on this page was last updated on 05 December, 2015, by Dr. Varun Gupta (MD Pharmacology)