Stanex E 450 mg/300 mg/800 mg Tablet


Overview

Uses of Stanex E Tablet

Stanex E 450 mg/300 mg/800 mg Tablet is used in the treatment of tuberculosis.

Stanex E Tablet side effects

Common
  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Teary eyes
  • Increased liver enzymes
  • Jaundice
  • Visual impairment
  • Increased uric acid level in blood
  • Gout
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Stanex E Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Stanex E 450 mg/300 mg/800 mg Tablet is to be taken empty stomach.
Avoid Stanex E 450 mg/300 mg/800 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Stanex E Tablet works

Stanex E 450 mg/300 mg/800 mg Tablet is a combination of three medicines: Rifampicin, isoniazid and ethambutol, which treats tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.

Stanex E Tablet related warnings

Alcohol
CAUTION
Stanex E 450 mg/300 mg/800 mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Pregnancy
WEIGH RISKS VS BENEFITS
Stanex E 450 mg/300 mg/800 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Stanex E 450 mg/300 mg/800 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Stanex E 450 mg/300 mg/800 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Stanex E 450 mg/300 mg/800 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Stanex E 450 mg/300 mg/800 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Stanex E 450 mg/300 mg/800 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Stanex E 450 mg/300 mg/800 mg Tablet may be needed. Please consult your doctor.

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FAQs

Q. Which is the best time to take Stanex E?

Take Stanex E exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Q. Can the use of Stanex E make birth control pills ineffective?

Yes, Stanex E can make birth control pills less effective. Ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Q. Is tuberculosis a curable disease?

Yes, tuberculosis (TB) is a curable disease and can be cured with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side effects.

Q. What are the instructions for the storage and disposal of Stanex E?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Stanex E cause discoloration of the urine?

Yes, Stanex E contains rifampicin which can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).

Q. Can I discontinue Stanex E if I feel well?

No, do not discontinue Stanex E. Take the proper course of the drug that has been prescribed to you even if you begin to feel better. If you stop taking Stanex E, your infection may become worse and difficult to treat. It may even result in drug-resistant TB i.e. drugs you were taking may no longer work for Tuberculosis.

Q. Can Stanex E cause visual impairment?

Stanex E contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
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