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29 Jul 2019 | 12:22 PM (IST)
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Slipizem 5mg Suppository

Prescription Required

Overview

Introduction

Slipizem 5mg Suppository is a prescription medicine used to treat seizures. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.

Slipizem 5mg Suppository is given under the supervision of a healthcare professional and it is inserted into the rectum. Take this medicine in the dose and duration as advised by your doctor as it has high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as it may cause nausea and anxiety. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.

Side effects of this medicine are very less but may cause abdominal discomfort. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Uses of Slipizem Suppository

Side effects of Slipizem Suppository

Common
  • Rectal discomfort

How to use Slipizem Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Slipizem Suppository works

Slipizem 5mg Suppository is a benzodiazepine (BZD). It is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it quickly increases the action of GABA, a chemical messenger. This action suppresses the abnormal and excessive activity of the nerve cells in the brain, thereby controlling seizures.

Safety Advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Slipizem 5mg Suppository is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Slipizem 5mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
CAUTION
Slipizem 5mg Suppository should be used with caution in patients with kidney disease. Dose adjustment of Slipizem 5mg Suppository may be needed. Please consult your doctor.
Dose adjustment may be required if it is to be given for a long period
Liver
CAUTION
Slipizem 5mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Slipizem 5mg Suppository may be needed. Please consult your doctor.

What if you forget to take Slipizem Suppository?

If you miss a dose of Slipizem 5mg Suppository, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Slipizem 5mg Suppository
₹11.2/Suppository
JUNIZ RDS SUPPOSITORY 5 MG
Elder Pharmaceuticals Ltd
₹12/Suppository
7% costlier

Quick Tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
  • Slipizem 5mg Suppository helps treat short term anxiety.
  • Safety of this medicine is not established for long-term use. Do not use it for more than 4 weeks. 

Interaction with Drugs

Taking Slipizem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
SERIOUS
Brand(s): Adesera, Adheb, Adfovir
SERIOUS
Brand(s): Stozen, Sulpigold, Amisulide
SERIOUS
Brand(s): Triptam
SERIOUS

Patient Concerns

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Bilateral mild hippocampal atrophy with mid sclerosis,is this curable?what are the effects of this she's having epilepsy,taking EPILIVE 250,3 for a day,LOBAZAM 5mg for a day.earlier she was taking LOBAZAM MD 5mg.please let me know whether she can have a normal life?or she has to be under parental care ?if so for how long?
Dr. Vikas Sharma
Neurologist
depends of frequency of seizures
This taplet have a blood pressure peasantSodium valproate tap let I. P
Dr. Khoobsurat Najma
Ask A Chemist
It is used to treat All forms of epilepsy, generalised epilepsy with absence seizures, prophylaxis of febrile convulsion, prophylaxis of post traumatic epilepsy, alcohol withdrawal, mania, nelsons syndrome.
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Do you have any questions related to Slipizem 5mg Suppository ?

FAQs

Q. Is Slipizem an antidepressant? What is it used for?

Slipizem is not an antidepressant and belongs to a group of medicines called benzodiazepine. It is used to treat severe anxiety (an emotional state where you may sweat, tremble, feel anxious and have a fast heartbeat) or agitation. It is also used to treat trembling, muscle spasm due to tetanus or poisoning, seizures or fits, confusional states or anxiety associated with alcohol withdrawal. It also helps in relaxing patients before minor operations or procedures.

Q. How long does it take for Slipizem to start working?

It depends on what you are taking Slipizem for. If you are taking it to treat anxiety, you should start feeling better within a few hours, but it may take a week or two before the full benefits become evident. Similarly, if you are taking it to relieve muscle spasm you may notice a difference after 15 minutes. Your muscles will start relaxing when you keep taking Slipizem regularly for a few days.

Q. Does Slipizem cause sleepiness? If yes, then should I stop driving while taking Slipizem?

Yes, Slipizem causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Slipizem makes you sleepy and affects your alertness, you should avoid driving.

Q. Is it safe to take Slipizem and alcohol together?

No, it is not at all recommended to take alcohol with Slipizem since it can cause breathing problems, sleepiness and heart problems. Taking Slipizem with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.

Q. Is Slipizem addictive?

People taking Slipizem in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Slipizem. Therefore, Slipizem should be taken for the shortest possible time and in the lowest effective dose.

Q. Can I stop taking Slipizem if I start feeling better?

No, do not stop taking Slipizem suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.

Q. For how long should I take Slipizem?

The duration of treatment with Slipizem is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need of continuation of treatment, especially if you do not have any symptoms. In general, the treatment does not last any longer than 8-12 weeks which includes the gradual reduction of dose process.

Q. Does Slipizem have any effect on contraception?

Slipizem does not affect the functioning of any type of contraception including the birth control pills and emergency contraception. Birth control pills can keep Slipizem in your body for a long time and increase its effect. You can also experience bleeding in between your periods if you take Slipizem and birth control pills together. But your contraceptive method will still work.

Q. Is it safe to take clozapine and Slipizem together?

No, it is not recommended to take clozapine and Slipizem together because the effects of both medicines may get added together. This can result in severe drop in blood pressure, breathing problems (respiratory depression) and can even stop your heart which can lead to death.

Q. Is Slipizem safe to be used in elderly patients?

The dose in elderly is generally half of the dose recommended to young people. This is because Slipizem causes muscle relaxation which can make the patient fall down, which may further lead to fractures.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Diazepam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 185-89.
  2. White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 462-63.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 389-91.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. DailyMed. Diazepam. [Accessed 22 Mar. 2019] (online) Available from:External Link
  6. MedlinePlus. Diazepam. [Accessed 20 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Bliss GVS Pharma Ltd., 102,Hyde Park, Saki Vihar Road, Andheri (East),Mumbai – 400072, India
NOT FOR SALE
We do not facilitate sale of this product at present

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