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SII-Onco-BCG Injection

Prescription Required
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

SII-Onco-BCG Injection is a medicine used for treatment of early-stage bladder cancer. It is recommended for people with early bladder cancer that has not yet reached the bladder muscle. It kills the cancer cells and reduces the risk of cancer coming back again (recur).

SII-Onco-BCG Injection is administered by a healthcare professional. It is instilled directly into the bladder through the urethra. For it to be effective, you should complete the course of the vaccine. You should not discontinue even if you get better until the course is completed.

Some common side effects of this medicines include difficulty in urination, urinary tract infection, and fever. These are usually mild and go away with time. However, if they persist or get worse, you should let your doctor know.

Before receiving the vaccine, you should let your doctor if you have ever had an allergic reaction to any vaccine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this vaccine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this vaccine.

Uses of SII-Onco-BCG Injection

Benefits of SII-Onco-BCG Injection

In Treatment of Early-stage bladder cancer

SII-Onco-BCG Injection helps to treat early stage bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse directly into your bladder through a catheter. It should not be self-administered.

Side effects of SII-Onco-BCG Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of SII-Onco-BCG

  • Urinary tract infection

How to use SII-Onco-BCG Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How SII-Onco-BCG Injection works

SII-Onco-BCG Injection is a type of bacteria. It works by activating the cells in the immune system which helps destroy cancer cells lining the bladder.

Safety advice

It is not known whether it is safe to consume alcohol with SII-Onco-BCG Injection. Please consult your doctor.
SII-Onco-BCG Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SII-Onco-BCG Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
SII-Onco-BCG Injection does not usually affect your ability to drive.
There is limited information available on the use of SII-Onco-BCG Injection in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of SII-Onco-BCG Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
SII-Onco-BCG Injection
Oncovac Vaccine
Zydus Cadila
10% costlier
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Quick tips

  • SII-Onco-BCG Injection helps treat bladder cancer and also prevents cancer from coming back after bladder surgery.
  • It is put into your bladder through a tube by a doctor or nurse.
  • Do not drink any liquid 4 hours before or 2 hours after you get this medicine.
  • You will be asked to urinate immediately before and 2 hours after SII-Onco-BCG Injection is given to you.
  • Inform your doctor if you are also taking medicines for tuberculosis, other medications such as antibiotics or those that affect the immune system.

Fact Box

Chemical Class
Habit Forming
Therapeutic Class
Action Class
Live attenuated vaccines

Interaction with drugs

Taking SII-Onco-BCG with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Thioprinz, Lazorin, Azarid
Brand(s): Empurine, Mercapto, Puri Nethol
Brand(s): Methosis, Metrex, Cytotrex
Brand(s): Healgraft

Patient concerns

He was advised solu medrol 500 mg injection for pain relief after he has been diagnosed with suspected bone cancer. How far it is safe? Also is radiation advisable ?
Dr. Akshat Goel
Please refer to a Onco-surgeon
He is suffering from joindis weather we can give him bcg vaccine or not He is 26days old joindis is seeing in his eyes only
Dr. Saurabh Gupta
Yes u can give bcg

User feedback


Q. What is SII-Onco-BCG Injection used for?

SII-Onco-BCG Injection is a medicine used to treat early stage bladder cancer. It is made from a weakened strain of Mycobacterium bovis, a vaccine for tuberculosis. SII-Onco-BCG Injection stimulates the immune system to attack cancer cells and this stops the cancer from growing as well as spreading to other unaffected parts.

Q. What are the side effects of using SII-Onco-BCG Injection?<br>

SII-Onco-BCG Injection can cause side effects like difficulty in urination, urinary tract infection, and fever. It also commonly causes a burning feeling in the bladder, the need to urinate often, and even blood in the urine.

Q. Are there any serious side effects of SII-Onco-BCG Injection?

Usually, you may have a fever as one of the common side effects of SII-Onco-BCG Injection. But if the fever is prolonged with a temperature of or above 101 degrees, or if you have chills, rash, prolonged cough, specific joint pain, or if any of these symptoms last longer than 48 hours, then you should contact your doctor immediately. Your doctor may prescribe some medications to relieve these side effects and may also suggest ways to cope up with them.

Q. Can SII-Onco-BCG Injection cause blood in the urine?

Yes, causes some irritation to the bladder and may cause bleeding that may give your urine a reddish color. Drink as much fluids as you can to keep your urine clear and to prevent blood clots from forming in the bladder. Usually, this bleeding resolves after sometime. But, if it does not or if it bothers you, consult your doctor.

Q. Is it safe to have an intercourse while on treatment with SII-Onco-BCG Injection?

No, one should refrain from having unprotected sexual intercourse while on treatment with SII-Onco-BCG Injection. In fact, men must wear a condom for the entire six-week treatment and women must avoid any vaginal contact for an additional six weeks after treatment too. This is to ensure safety of the other partner, because SII-Onco-BCG Injection does not contain dead but weakened bacteria. So, it may affect the unaffected individuals and therefore is advised not to indulge in sexual contact.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. pp. 190-91.
  2. CiplaMed. Onco-BCG Injection. [Accessed 04 Apr. 2019] (online) Available from:External Link
  3. Serum Institute of India. Bacillus Calmette-Guerin strain. [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India
Country of origin: India
Inclusive of all taxes
MRP645.95  13% OFF
1 Injection in 1 vial
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