Sibofix 400mg Tablet

Dr Reddy's Laboratories Ltd

Composition for Sibofix 400mg Tablet

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Primarily used for

Hepatic encephalopathy
10 tablets in 1 strip

Medicine Overview of Sibofix Tablet


Uses of Sibofix Tablet

Sibofix 400mg Tablet is used in hepatic encephalopathy
It is also used in the treatment of infectious diarrhoea in adult and children (>2years of age and above).

Side effects of Sibofix Tablet


Nausea, Vomiting, Dizziness, Headache, Flatulence, Bloating, Constipation.


How to use Sibofix Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Sibofix 400mg Tablet at a fixed time.

How Sibofix Tablet works

Sibofix 400mg tablet is an antibiotic. It works by killing the ammonia-producing bacteria in the gastrointestinal tract which reduces recurrence of hepatic encephalopathy.

In Depth Information on Sibofix Tablet

Expert advice for Sibofix Tablet

While you are taking rifaximin, it may cause a reddish discolouration of the urine. This is quite normal. If you are using oral contraceptives take additional precautions while taking rifaximin. Oral contraceptives may not work as well when you are taking this medicine and/or when you have diarrhea. Rifaximin does not normally affect the ability to drive and use machines, but may cause dizziness in some patients. If you feel dizzy you should not drive or operate machinery. if you are pregnant or breast feeding speak to your doctor before starting the drug. To make sure rifaximin is safe for you, tell your doctor if you have:
  • liver disease
  • diarrhea with a fever
  • watery or bloody diarrhea
Treatment with any antibiotic including rifaximin may cause severe diarrhea. You should stop taking it and contact your doctor immediately. Diarrhea may even occur few months after the drug has been stopped.
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Special precautions for Sibofix 400mg Tablet
Interaction with alcohol is unknown. Please consult your doctor.
Sibofix 400mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Sibofix 400mg Tablet is probably safe to use during lactatio
n. Limited human data suggests that the drug does not represent a significant risk to the baby.
Sibofix 400mg Tablet does not usually affect your ability to drive.
Sibofix 400mg Tablet is probably safe to use in patients wit
h kidney disease. Limited data available suggests that dose adjustment of Sibofix 400mg Tablet may not be needed in these patients. Please consult your doctor.
Sibofix 400mg Tablet should be used with caution in patients
with severe liver disease. Dose adjustment of Sibofix 400mg Tablet may be needed. Please consult your doctor.

Missed Dosageuses

If you miss a dose of Rifaximin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Sibofix 400mg Tablet

Frequently asked questions for Rifaximin

Yes, Sibofix is an antibiotic that kills bacteria, which can cause a disease called hepatic encephalopathy (symptoms include agitation, confusion, muscle problems, difficulty in speaking and in some cases coma).
Q. Can I take Sibofix with amoxicillin?
Sibofix can be taken with amoxicillin as no interactions have been reported between the two medicines. However, interactions may occur, please consult your doctor before taking the two medicines together.
Sibofix is an antibiotic and kills bacteria but it does not kill parasites and yeast.
Yes, Sibofix is a safe medicine. However, it has its own side effects. It should always be taken for a prescribed duration in prescribed doses as advised by your doctor.
Sibofix is not a penicillin. It is a non-aminoglycoside semi-synthetic, nonsystemic antibiotic derived from rifamycin .
No, Sibofix is not a sulfa drug. It's a rifamycin derivative.
Sibofix like other antibiotics can alter the normal bacteria in the intestine and this can lead to severe diarrhea.
Sibofix is not indicated for the treatment of small intestinal bacterial overgrowth (SIBO). In this condition, there is a presence of lot of bacteria in the small intestine which can cause chronic diarrhea and malabsorption.
Yes, the use of Sibofix may cause a reddish discoloration of the urine.
Interactions have not been reported between Sibofix and oral contraceptives (birth control pills). However, interactions may occur. Please consult your doctor before taking the two medicines together.
Sibofix has not been approved for the treatment of irritable bowel syndrome (IBS). Please consult your doctor before using Sibofix for irritable bowel syndrome (IBS).
Weight gain has not been reported as an effect of Sibofix.
Diarrhea is a common side effect of Sibofix. If you have severe diarrhea during or after using Sibofix, you should stop taking Sibofix and contact your doctor immediately.
Sibofix has not been reported to kill Helicobacter pylori.
Q. Can paracetamol be taken with Sibofix?
Sibofix can be taken with paracetamol as no interactions have been clinically observed between paracetamol and Sibofix. However, interactions may occur. Please talk to your doctor in case you require to take the two medicines together.
Q. Can I take Sibofix with ibuprofen?
Sibofix can be taken with ibuprofen as no interactions have been clinically observed between the two. However, interactions may occur. Please talk to your doctor in case you require to take the two medicines together.
Constipation is a rare side effect of Sibofix. Please consult your doctor in case you experience intolerable constipation.

User Submitted Feedback For Sibofix 400mg Tablet

One of the following vendor pharmacies will deliver Sibofix 400mg Tablet: Health Arx Technologies Private Limited, Amishi Consumer Technologies P Ltd, Organic India Private Limited, Delhi Cryogenic Products Pvt Ltd, First Step Digital Pvt Ltd, Gupta Homoeo Pharmacy Pvt Ltd, Natures Velvet Lifecare, Organic Wellness Products Private Limited, RK Sons, Pills Tree Super Pharmacy, Melting Pot Concepts Pvt Ltd, Zywie Ventures Pvt Ltd, SBL Pvt Ltd, Lifecare Chemist (PAN India), Satyog Enterprises Pvt Ltd, Ghantakarn International, Aashirwad Agency, Airveda Technologies Pvt Ltd, Fit and Glow Healthcare Pvt Ltd, Keshav Homeo Home, Radicura Pharmaceuticals Pvt Ltd, Perfect Nutrition, Jiva Ayurvedic Pharmacy Ltd, Sharma Traders, Bright Lifecare Pvt Ltd, Delhi Vendor, Maximaa Systems Ltd, Swadeshi Ayurved, Sri Jain Pharmacy, Inlife Pharma Pvt Ltd, Herbolab India Pvt Ltd, Ayush Enterprises, Priya Entreprises, Gallop Trading Company, Planet Ayurveda, Life aid Homeopathic and ayurvedic store, Emmbros Overseas, Makvis, Herboveda India, Hexagon Nutrition Pvt. Ltd., Rusan Healthcare Pvt Ltd, Delhi Distributors, BestSource Nutrition Private Limited, Biomed Distributors, Star medicare, DF Pharmacy Ltd, Do You Even Gym, 9 to 9 Farmacia, The Medicine Mart, Bantom Laboratories P Ltd , 9to9 Farmacia (South), Madhu Medicos, M/s R&G Healthcare (Delhi), OHMS GROUP, Adret Retail Pvt. Ltd.

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Top Physicians
Dr. Sunil Sekhri
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