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Rifaximin(400 mg)


Rifaximin(400 mg)


Rifaximin is an antibiotic used to treat bacterial infections of the intestine (traveller's  diarrhea). Rifaximin is also used to lower the risk of worsened brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.

How it works

Rifaximin is a broad spectrum antibacterial drug that fights bacterial infection only in the intestines. Rifaximin stops the growth of bacteria that produce toxins and that may worsen liver disease.

Common side effects

reduced sense of touch, swelling of ankles, shortness of breath, convulsions, urinary infection, loss of or poor memory, joint pain, falls, yeast infections, loss of concentration, accumulation of fluid in the abdominal cavity, difficulty or pain passing urine, feet or fingers, feeling sleepy, depressed mood, confusion, urge to vomit, Stomach ache or bloating/swelling, feeling unsteady, fluid around the lungs, hot flushes, needing to pass urine more often than usual, loss of appetite, rash or itching, diarrhea, muscle pain., dizziness, fever, anxiety, difficulty sleeping, swelling due to too much fluid in the body, anemia, muscle cramps, dry mouth, vomit, headache


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Expert advice

While you are taking rifaximin, it may cause a reddish discolouration of the urine. This is quite normal. If you are using oral contraceptives take additional precautions while taking rifaximin. Oral contraceptives may not work as well when you are taking this medicine and/or when you have diarrhea. Rifaximin does not normally affect the ability to drive and use machines, but may cause dizziness in some patients. If you feel dizzy you should not drive or operate machinery. if you are pregnant or breast feeding speak to your doctor before starting the drug. To make sure rifaximin is safe for you, tell your doctor if you have:
  • liver disease
  • diarrhea with a fever
  • watery or bloody diarrhea
Treatment with any antibiotic including rifaximin may cause severe diarrhea. You should stop taking it and contact your doctor immediately. Diarrhea may even occur few months after the drug has been stopped.

Frequently asked questions


Q. Is rifaximin an antibiotic/ is rifaximin FDA approved for irritable bowel syndrome (IBS)/help in IBS?
Yes, rifaximin (also available as Rifagut) is an antibiotic. It is not yet approved by the FDA for the treatment of IBS.

Q. Is rifaximin safe/ safe in pregnancy?
Rifaximin is safe if used at prescribed doses for the prescribed duration as advised by your doctor. Its safety in pregnant women has not been established. Patients should follow the advice of the doctor regarding its use.

Q. Is rifaximin available over the counter/ is it available in UK/ Canada/ Australia?
No, it is available only with your doctor's prescription. It is available in UK, Canada, Australia.

Q. Is rifaximin the same as rifampin?
Rifaximin is a structural analog of rifampin.

Q. Is rifagut an antibiotic?
Rifagut is a brand name for rifaximin. Yes, it is an antibiotic.

Q. Can I take xifaxan with amoxicillin/ibuprofen?
Xifaxan is the brand name for rifaximin and can be taken with ibuprofen, but not with amoxicillin, as it is antibiotic. If taken with other antibiotics, rifaximin causes diarrhea.

Q. Does rifaximin cause diarrhea/gas/constipation?
It may rarely cause these side effects.

Q. Does rifaximin kill parasites/yeast?
It is antibiotic and doesn’t kill parasites and yeast.

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