Sazo EN 500mg Tablet

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Medley Pharmaceuticals

Composition for Sazo EN 500mg Tablet

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88
₹8.8/Tablet
10 tablets in 1 strip
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Medicine Overview of Sazo EN Tablet

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Uses of Sazo EN Tablet

Sazo EN 500mg Tablet is used in the treatment of rheumatoid arthritis, ulcerative colitis, Crohn’s disease and ankylosing spondylitis.
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Side effects of Sazo EN Tablet

Common

Nausea, Headache, Skin rash, Loss of appetite, Increased body temperature.

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How to use Sazo EN Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Sazo EN 500mg Tablet with food.

How Sazo EN Tablet works

Sazo en 500mg tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

In Depth Information on Sazo EN Tablet

Expert advice for Sazo EN Tablet

  • Inform your doctor if you ever had any form of drug allergy. 
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding. 
  • Inform your doctor if you have a fertility problem. Sazo en may cause a fall in sperm count, so may lead to a temporary decrease in male fertility, but can be reversed if treatment is stopped.
  • Inform your doctor if you are suffering from any blood disease e.g. G6PD deficiency. 
  • Your doctor may ask to get some blood test before you start treatment and also during the course of treatment.
  • You may have to wait for 6 to 12 weeks to get the full effect.
  • You may experience loss of appetite and nausea when treatment is started.
  • Your urine may change color (to orange) but there is nothing to worry about.
  • Drink plenty of water while on treatment with Sazo en. This helps to prevent kidney stone and kidney damage.
  • You should tell your doctor about all medicines you are taking or plan to take. This includes ayurvedic or herbal/naturopathic medicines.
  • Inform your doctor right away if you have any of the following problems: a sore throat or fever or any sign of infection.
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Warnings
Special precautions for Sazo EN 500mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
PROBABLY SAFE
Sazo EN 500mg Tablet is probably safe to use during pregnancy.

Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
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Lactation
CAUTION
Sazo EN 500mg Tablet is probably usafe to use during lactati
on. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
Sazo EN 500mg Tablet does not usually affect your ability to drive.
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Kidney
CAUTION
Sazo EN 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazo EN 500mg Tablet may be needed. Please consult your doctor.

Regular monitoring of kidney function tests is advisable while you are taking this medicine.
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Liver
UNSAFE
Sazo EN 500mg Tablet is probably unsafe to use in patients w
ith liver disease and should be avoided. Please consult your doctor.
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Severely interacts with other drugs like
Captomer 50mg Tablet, Zesoris-AZ 50mg Tablet, Autorin 50mg Tablet, Azoprine 50mg Tablet

Missed Dosageuses

If you miss a dose of Sulfasalazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Sazo EN 500mg Tablet

Frequently asked questions for Sulfasalazine

Q. Is Sazo en a DMARDs?
Yes, Sazo en is a DMARDs (Disease-Modifying Antirheumatic Drugs). It prevents joint damage and preserves joint mobility.
Q. Can I use Sazo en 1gram BD?
Yes, Sazo en can be used as 1gm BD (twice daily) if you have severe disease.
Q. How is Sazo en metabolized?
Sazo en is metabolized in the colon by the bacterial enzyme azoreductase to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. How long does Sazo en take to produce the effect?
Sazo en does not work right away. It will take about 6 to 12 weeks to get the full effect.
Q. Where is sulfasalazine absorbed?
Sazo en is absorbed in the intestine (jejunum and colon). In the colon, it breaks down to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. Can I use Sazo en with hepatitis B?
Yes, Sazo en is relatively safe in hepatitis B infection.
Q. Can I use Sazo en in hepatitis C?
Sazo en should not be used in hepatitis C patients with bad prognosis.
Q. Sazo en for alopecia areata?
Sazo en is not approved for treatment of alopecia areata.
Q. Sazo en for gout?
Sazo en is not approved for treatment of gout.
Q. Sazo en for IBS (irritable bowel syndrome)?
Sazo en is not approved for treatment of irritable bowel syndrome (IBS).
Q. Sazo en for IBD(inflammatory bowel disease)?
Yes, Sazo en is used in the treatment of inflammatory bowel disease (IBD).
Q. Sazo en for psoriatic arthritis?
Sazo en is a DMARD that may be effective for the joint pain and skin lesions associated with psoriatic arthritis.
Q. Sazo en for psoriasis?
Sazo en is not approved for psoriasis.
Q. Can I use Sazo en with vitamin c?
Yes, Sazo en can be used with vitamin c.
Q. Can I use Sazo en with vitamin d?
Yes, Sazo en can be used with vitamin d.
Q. Sazo en vs mesalamine?
Mesalamine and Sazo en are both used in the treatment of ulcerative colitis. Sazo en having fewer side effects as compared to mesalamine.
Q. Sazo en vs balsalazide?
Balsalazide has a better tolerability than Sazo en in patients with ulcerative colitis.
Q. Sazo en with folic acid?
Sazo en inhibits the absorption and metabolism of folic acid.which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia). This can be normalized by administration of folic acid or folinic acid (leucovorin).
Q. Sazo en interaction with methotrexate?
Coadministration of Sazo en and methotrexate do not alter the pharmacokinetic disposition of the drugs. It may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Sazo en with meloxicam?
Meloxicam and Sazo en cause kidney problem if given together.
Q. Sazo en with antibiotics?
People who are allergic to sulfa drugs antibiotics like cotrimoxazole, sulfisoxazole etc, may have a cross reaction to Sazo en and should therefore not take it.
Q. Sazo en with prednisone?
Sazo en can be given in conjunction with steroids (prednisone) as part of an intensive management regime during the severe attack of rheumatoid arthritis.
Q. Sazo en with adalimumab?
Adalimumab can be used with Sazo en in the treatment of moderate to severe, active rheumatoid arthritis in adult patients when the response to disease-modifying antirheumatic drugs (DMARDs) is inadequate.
Q. Sazo en with the sulfa allergy?
Patients with sulfa drug allergy should avoid Sazo en.
Q. Sazo en with naproxen?
Sazo en is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g naproxen.
Q. Sazo en with ibuprofen?
Sazo en is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g ibuprofen.
Q. Sazo en with methotrexate side effects?
Taking Sazo en and methotrexate together may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Sazo en with hydroxychloroquine?
Sazo en and hydroxychloroquine combination have shown better and faster response in rheumatoid arthritis.
Q. Allergic to Sazo en?
You should not take Sazo en, if you are allergic to Sazo en.
Q. Is Sazo en a prodrug?
Yes, Sazo en is a prodrug. It gets converted into sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) in the body.
Q. Is Sazo en a sulfa drug?
Yes, Sazo en is a sulfa drug because it contains sulfonamide (sulfapyridine) as active ingredients.
Q. Is Sazo en an antibiotic?
Sazo en is a combination of antibiotic sulfapyridine and 5 aminosalicylic acid, mainly used in inflammatory bowel disease and rheumatoid arthritis.
Q. Is Sazo en enteric coated?
Some formulation of Sazo en may be available as enteric-coated. Enteric coating is done to prevent the tablet destruction by stomach acid.
Q. Sazo en causes weight loss?
Yes, Sazo en can cause loss of appetite which may lead to loss of weight.
Q. Can Sazo en cause rash?
Yes, Sazo en can cause the rash as a side effect.
Q. What is the Sazo en drug class?
Sazo en belongs to sulfonamide drug class.
Q. What is Sazo en delayed-release tablets?
Sazo en delayed release tablets are the enteric coated tablets, which prevent the disintegration of the drug when they come in contact with stomach acid.
Q. Sazo en cause insomnia?
Yes, Sazo en can cause insomnia as a side effect.
Q. Sazo en flu-like symptoms?
Sazo en can cause flu-like symptoms like aching of joints, fever, headache, sore throat, rashes.
Q. Sazo en for ulcerative colitis?
Ulcerative colitis is an inflammatory bowel disease. Sazo en releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in ulcerative colitis.
Q. Sazo en for Crohn's disease?
Crohn's disease is an inflammatory bowel disease. Sazo en releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in Crohn's disease.
Q. Sazo en in cancer patients?
Sazo en is not approved for treatment of cancer.
Q. Why does Sazo en cause blood disorders?
Sazo en inhibits the absorption and metabolism of folic acid. Which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia).
Q. Why does Sazo en cause a sore throat?
Sazo en suppresses the immune system which can manifest with the sign of infections like a sore throat or fever.
Q. What does Sazo en contain?
Sazo en contains sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) as active ingredients.
Q. Side effects of stopping sulfasalazine?
If Sazo en is stopped, patient can experience withdrawal symptoms like depression, pain, stress, anxiety, back pain, and muscle spasticity.
Q. Sazo en withdrawal?
Sazo en withdrawal can cause depression, pain, stress, anxiety, back pain and muscle spasticity.
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User Submitted Feedback For Sazo EN 500mg Tablet

Survey Participants: 5
Disclaimer
“The following are the results of on-going survey on 1mg.com for Sazo EN 500mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
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