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Sazo EN 500 mg Tablet

Medley Pharmaceuticals

Composition for Sazo EN 500 mg Tablet

Prescription Required

Primary uses of Sazo EN 500 mg Tablet

MRP
88
₹8.8/Tablet
10 tablets in 1 strip
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Medicine Overview of Sazo EN Tablet

Uses of Sazo EN Tablet

Sazo EN 500 mg Tablet is used in the treatment of ankylosing spondylitis, ulcerative colitis, Crohn’s disease and rheumatoid arthritis.

Sazo EN Tablet side effects

Common

Side Effects of Sazo EN are Nausea, Headache, Skin rash, Loss of appetite, Increased body temperature.

How to use Sazo EN Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazo EN 500 mg Tablet is to be taken with food.

How Sazo EN Tablet works

Sazo EN 500 mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling). It has an additional anti-bacterial property which helps prevent bacterial growth.
In Depth Information on Sazo EN Tablet

Expert advice for Sazo EN Tablet

  • You have been prescribed Sazo EN 500 mg Tablet to control the symptoms and slow down the progression of inflammatory bowel disease or rheumatoid arthritis.
  • Take it with food to avoid an upset stomach.
  • It may take 6-8 weeks for Sazo EN 500 mg Tablet to work. Keep taking it as prescribed.
  • Drink plenty of fluids while taking Sazo EN 500 mg Tablet in order to avoid problems with your kidneys such as kidney stones.
  • Do not take Sazo EN 500 mg Tablet if you are allergic to sulfa drugs or aspirin.
  • It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
  • Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
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Sazo EN Tablet related warnings

Special precautions for Sazo EN Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
PROBABLY SAFE
Sazo EN 500 mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
CAUTION
Sazo EN 500 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
SAFE
Sazo EN 500 mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Sazo EN 500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazo EN 500 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Liver
UNSAFE
Sazo EN 500 mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you miss a dose of Sazo EN Tablet?

uses
If you miss a dose of Sazo EN 500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Questions Related to Sazo EN

Treatment for ankylosing spondilytisIs there treatment of a.s.
Dr. Ila Jain Khandelwal
Pathologist
Yes there is treatment available for ankylosing spondylitis. You can try alternate forms like yoga, physiotherapy. You should ideally consult a orthopedecian for the same.
Treatment of Ankylosing spondilytis
Dr. Ila Jain Khandelwal
Pathologist
Yes there is treatment available for ankylosing spondylitis. You can try alternate forms like yoga, physiotherapy. You should ideally consult a orthopedecian for the same.
I suffer heavy pain in my both hips. Doctor says I should change both hips. In My MRI report ankylosing spondylitis show.
Dr. Vipul Aggarwal
Bone & Joint Specialist
If thehip joint is completely destroyed then the only suitable option is hip replacement please send me the x-rays so that I can have a look at it
Having severe ankylosing spondylitisSazo 1000 mg along with calcijoint tab one perday going on. Still problem persists.Please suggest more on this
Dr. Akshat Goel
Bone & Joint Specialist
Take sazo twice dailyAnd take Tab Tolpazen twice daily for 5 daysApply Dynapar QPS spray
I had a severe pain in vertebral column especially in neck region and lower back from last 1 year i am saportsman n play badminton n cricket bt when i do not play i cant evem stand for more than 30 min n difficulty i reading for mire than 15 min previously treated with indomethacin nsaids
Dr. Akshat Goel
Bone & Joint Specialist
Please get a Digital X-rays done of Cervical spine and Dorsal spine Both AP and Lateral viewsYou might be suffering with Ankylosing spondylitisAlso undergo a test HLAB27
Severe pain in left foot and right thigh from almost 2 months.
Dr. Akshat Goel
Bone & Joint Specialist
You have Ankylosing Spondylitis you need to exercise all joints of your body daily Especially hips, spine and mouth Take Tab Indocap-SR twice daily and Tab Flotrip-forte thrice daily for 6-7days and Tab SAAZ 500mg once daily for 2 monthsAlso meet a Rheumatologist for the same
I m suffering from Hla b 27. Can I use Flexabenz plush or any other medicines plz provide me my e-mail if. I m in very painful.
Dr. Vipul Aggarwal
Bone & Joint Specialist
I can understand ur problemIts a trouble to have ankylosing spondylitisMain stay of treatment from Orthopedic point of view is core stability exercisesMedcines are now days written by rheumatologistThe problem can be controlled There is no definite permanent cure for it

User Submitted Feedback For Sazo EN 500 mg Tablet

Survey Participants: 5
Disclaimer
“The following are the results of on-going survey on 1mg.com for Sazo EN 500 mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”

Frequently asked questions about Sazo EN Tablet

Frequently asked questions about Sulfasalazine
Q. Is Sazo EN a DMARDs?
Yes, Sazo EN is a DMARDs (Disease-Modifying Antirheumatic Drugs). It prevents joint damage and preserves joint mobility.
Q. Can I use Sazo EN 1gram BD?
Yes, Sazo EN can be used as 1gm BD (twice daily) if you have severe disease.
Q. How is Sazo EN metabolized?
Sazo EN is metabolized in the colon by the bacterial enzyme azoreductase to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. How long does Sazo EN take to produce the effect?
Sazo EN does not work right away. It will take about 6 to 12 weeks to get the full effect.
Q. Where is sulfasalazine absorbed?
Sazo EN is absorbed in the intestine (jejunum and colon). In the colon, it breaks down to sulfapyridine and 5 aminosalicylic acid (5-ASA).
Q. Can I use Sazo EN with hepatitis B?
Yes, Sazo EN is relatively safe in hepatitis B infection.
Q. Can I use Sazo EN in hepatitis C?
Sazo EN should not be used in hepatitis C patients with bad prognosis.
Q. Sazo EN for alopecia areata?
Sazo EN is not approved for treatment of alopecia areata.
Q. Sazo EN for gout?
Sazo EN is not approved for treatment of gout.
Q. Sazo EN for IBS (irritable bowel syndrome)?
Sazo EN is not approved for treatment of irritable bowel syndrome (IBS).
Q. Sazo EN for IBD(inflammatory bowel disease)?
Yes, Sazo EN is used in the treatment of inflammatory bowel disease (IBD).
Q. Sazo EN for psoriatic arthritis?
Sazo EN is a DMARD that may be effective for the joint pain and skin lesions associated with psoriatic arthritis.
Q. Sazo EN for psoriasis?
Sazo EN is not approved for psoriasis.
Q. Can I use Sazo EN with vitamin c?
Yes, Sazo EN can be used with vitamin c.
Q. Can I use Sazo EN with vitamin d?
Yes, Sazo EN can be used with vitamin d.
Q. Sazo EN vs mesalamine?
Mesalamine and Sazo EN are both used in the treatment of ulcerative colitis. Sazo EN having fewer side effects as compared to mesalamine.
Q. Sazo EN vs balsalazide?
Balsalazide has a better tolerability than Sazo EN in patients with ulcerative colitis.
Q. Sazo EN with folic acid?
Sazo EN inhibits the absorption and metabolism of folic acid.which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia). This can be normalized by administration of folic acid or folinic acid (leucovorin).
Q. Sazo EN interaction with methotrexate?
Coadministration of Sazo EN and methotrexate do not alter the pharmacokinetic disposition of the drugs. It may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Sazo EN with meloxicam?
Meloxicam and Sazo EN cause kidney problem if given together.
Q. Sazo EN with antibiotics?
People who are allergic to sulfa drugs antibiotics like cotrimoxazole, sulfisoxazole etc, may have a cross reaction to Sazo EN and should therefore not take it.
Q. Sazo EN with prednisone?
Sazo EN can be given in conjunction with steroids (prednisone) as part of an intensive management regime during the severe attack of rheumatoid arthritis.
Q. Sazo EN with adalimumab?
Adalimumab can be used with Sazo EN in the treatment of moderate to severe, active rheumatoid arthritis in adult patients when the response to disease-modifying antirheumatic drugs (DMARDs) is inadequate.
Q. Sazo EN with the sulfa allergy?
Patients with sulfa drug allergy should avoid Sazo EN.
Q. Sazo EN with naproxen?
Sazo EN is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g naproxen.
Q. Sazo EN with ibuprofen?
Sazo EN is used in the treatment of rheumatoid arthritis who has failed to respond to non-steroidal anti-inflammatory drugs (NSAIDs) e.g ibuprofen.
Q. Sazo EN with methotrexate side effects?
Taking Sazo EN and methotrexate together may increase the incidence of gastrointestinal adverse events, especially nausea.
Q. Sazo EN with hydroxychloroquine?
Sazo EN and hydroxychloroquine combination have shown better and faster response in rheumatoid arthritis.
Q. Allergic to Sazo EN?
You should not take Sazo EN, if you are allergic to Sazo EN.
Q. Is Sazo EN a prodrug?
Yes, Sazo EN is a prodrug. It gets converted into sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) in the body.
Q. Is Sazo EN a sulfa drug?
Yes, Sazo EN is a sulfa drug because it contains sulfonamide (sulfapyridine) as active ingredients.
Q. Is Sazo EN an antibiotic?
Sazo EN is a combination of antibiotic sulfapyridine and 5 aminosalicylic acid, mainly used in inflammatory bowel disease and rheumatoid arthritis.
Q. Is Sazo EN enteric coated?
Some formulation of Sazo EN may be available as enteric-coated. Enteric coating is done to prevent the tablet destruction by stomach acid.
Q. Sazo EN causes weight loss?
Yes, Sazo EN can cause loss of appetite which may lead to loss of weight.
Q. Can Sazo EN cause rash?
Yes, Sazo EN can cause the rash as a side effect.
Q. What is the Sazo EN drug class?
Sazo EN belongs to sulfonamide drug class.
Q. What is Sazo EN delayed-release tablets?
Sazo EN delayed release tablets are the enteric coated tablets, which prevent the disintegration of the drug when they come in contact with stomach acid.
Q. Sazo EN cause insomnia?
Yes, Sazo EN can cause insomnia as a side effect.
Q. Sazo EN flu-like symptoms?
Sazo EN can cause flu-like symptoms like aching of joints, fever, headache, sore throat, rashes.
Q. Sazo EN for ulcerative colitis?
Ulcerative colitis is an inflammatory bowel disease. Sazo EN releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in ulcerative colitis.
Q. Sazo EN for Crohn's disease?
Crohn's disease is an inflammatory bowel disease. Sazo EN releases 5 aminosalicylic acid which decreases inflammation of the intestines and thus helpful in Crohn's disease.
Q. Sazo EN in cancer patients?
Sazo EN is not approved for treatment of cancer.
Q. Why does Sazo EN cause blood disorders?
Sazo EN inhibits the absorption and metabolism of folic acid. Which may cause folic acid deficiency. This can result in serious blood disorders (e.g., macrocytosis and pancytopenia).
Q. Why does Sazo EN cause a sore throat?
Sazo EN suppresses the immune system which can manifest with the sign of infections like a sore throat or fever.
Q. What does Sazo EN contain?
Sazo EN contains sulfonamide (sulfapyridine) and 5 aminosalicylic acid (5-ASA) as active ingredients.
Q. Side effects of stopping sulfasalazine?
If Sazo EN is stopped, patient can experience withdrawal symptoms like depression, pain, stress, anxiety, back pain, and muscle spasticity.
Q. Sazo EN withdrawal?
Sazo EN withdrawal can cause depression, pain, stress, anxiety, back pain and muscle spasticity.

Severely interacts with other drugs like

Taking Sazo EN with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Sazo EN with Azathioprine
SERIOUS
Medicines with composition Azathioprine: Thioprinz, Lazorin, Azarid, Azap, Azoprine, Thiopress, Azofit, Azoran, Aretha, Azithioprine
Sazo EN with Digoxin
SERIOUS
Medicines with composition Digoxin: Cardisip, Digover, Digon, Cardioxin, Sangoxin, Digitran, Digoxin
Sazo EN with Mercaptopurine
SERIOUS
Medicines with composition Mercaptopurine: Empurine, Mercapto, Puri Nethol, Purinetone, 6-MP, Captomer, Mercapthol
Sazo EN with Folic Acid
BENEFICIAL
Medicines with composition Folic Acid: Rifol, Folistar, Folacid, Ptero, UPF, Icefol, Folimac, Folistat, Foly, Folmine
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